COVID-19 vaccination in India

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COVID-19 vaccination programme
India Vaccination Map.jpg
Per capita fully vaccination map as of 22 January 2022
Date16 January 2021 (2021-01-16) – present
(3 years, 17 days ago)
LocationIndia India
CauseCOVID-19 pandemic in India
TargetImmunisation of Indians against COVID-19
Budget₹35,000 crore (US$4.9 billion)[1]
Organised byGovernment of India
Indian Council of Medical Research
State governments of India
Participants
  • 1,012,558,641 people with one dose administered of Covaxin or Oxford–AstraZeneca vaccine or Sputnik V
  • 904,031,986 people have been fully vaccinated with both doses of Covaxin or Oxford–AstraZeneca vaccine or Sputnik V or Corbevax
  • 40,146,387 people have been administered Precautionary/Booster doses of Covaxin or Oxford–AstraZeneca vaccine or Sputnik V or Corbevax
Outcome
  • 73% of the Indian population has received one dose.
  • 65% of the Indian population has received both doses
Websitewww.mohfw.gov.in,
www.cowin.gov.in
As on 12th March 2022 (04:00PM)
Part of a series on the
COVID-19 pandemic
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Impact
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India began administration of COVID-19 vaccines on 16 January 2021. As of 17 June 2022, India has administered over 1.9 billion doses overall, including first, second and precautionary (booster) doses of the currently approved vaccines.[2][3] In India, 93% of the eligible population (12+) has received at least one shot, and 83% of the eligible population (12+) is fully vaccinated.[4][5]

India initially approved the Oxford–AstraZeneca vaccine (manufactured under license by Serum Institute of India under the trade name Covishield) and Covaxin (a vaccine developed locally by Bharat Biotech). They have since been joined by the Sputnik V (manufactured under license by Dr. Reddy's Laboratories, with additional production from Serum Institute of India being started in September[6][7]), Moderna vaccines, Johnson & Johnson vaccine and ZyCoV-D (a vaccine locally developed by Zydus Cadila)[lower-alpha 1][lower-alpha 2] and other vaccine candidates undergoing local clinical trials.

According to a June 2022 study published in The Lancet, COVID-19 vaccination in India prevented an additional 4.2 million deaths from December 8, 2020, to December 8, 2021.[8][9]

Vaccination programme[edit]

Cumulative doses administered across the country[edit]

Total doses administered across the country as of June 17, 2022 [10][5]

Dose Vaccination (Percentage of eligible population vaccinated)
Partially Vaccinated
1,012,558,641(93.39)
Fully Vaccinated
904,031,986(83.38)
Precautionary(Booster) Dose
40,146,387

Monthly graph of cumulative doses administered across the country

Graph of daily doses administered across the country[edit]

Graph of daily doses administered. Last updated: June 17, 2022[11]

   Daily vaccinations (1st dose only)    Daily vaccinations (2nd dose only)

Vaccine administration by Gender[edit]

Vaccinations in India by Gender as of June 17, 2022[10][5]

Gender Vaccination
Male 97,54,62,145
Female 93,81,13,507
Others 4,63,456

Vaccine administration by vaccine brand[edit]

Vaccinations in India by Vaccine Brand as of June 17, 2022 [10][5]

Brand Vaccination
Covishield 1,56,80,95,059
Covaxin 32,78,19,340
Sputnik V 12,24,641
Corbevax 5,60,57,093
Covovax 5,581

Vaccine administration by age group[edit]

Vaccinations in India by Age Group as of June 17, 2022 [10][5]

Age Group Vaccination
12-14 5,60,57,044
15-17 10,74,94,435
18-44 1,10,22,70,060
45-60 41,25,16,670
60+ 27,10,80,332

States by Vaccine Coverage[edit]

Note icon.svg (as of 15 September (7:00 IST))

Number of Vaccination Centres[edit]

Sites conducting vaccination in India
Emojione BW 1F3E5.svgVaccine - The Noun Project.svg
Total-1,12,700
• Government[fn 1] — 1,10,000
• Private[fn 2] — 2,700

Source: CoWin Dashboard[12]

Citizens above the age of 15 can book appointments through the COWIN platform or can do a Walk-In registration on site. All vaccine centres have registration desks, vaccine booths and observation rooms. Vaccine certificates can be downloaded digitally through the COWIN platform, or citizens can ask for a hard copy from vaccination centres. All government run vaccination centers provide free of cost vaccines, private centers do charge.[13]

Background and timeline[edit]

A vaccination centre in Delhi.
India's COVID-19 vaccination deployment until 3 June

First Phase, initial approvals, launch of vaccination programme[edit]

In September 2020, India's Health minister Harsh Vardhan stated that the country planned to approve and begin distribution of a vaccine by the first quarter of 2021.[14] The first recipients were to be 30 million health workers directly dealing with COVID patients.[15]

A vial of Covishield, the Indian-manufactured version of the AstraZeneca vaccine.
A vial of Covaxin
Vaccination drive for COVID prevention in Bhopal, India

On 1 January 2021, the Drug Controller General of India (DCGI) approved emergency use of the Oxford–AstraZeneca vaccine (local trade name "Covishield").[16][17][18] On 2 January, the DCGI also granted an interim emergency use authorisation to BBV152 (trade name "Covaxin"), a domestic vaccine developed by Bharat Biotech in association with the Indian Council of Medical Research and National Institute of Virology.[19] This approval was met with some concern, as the vaccine had not then completed phase 3 clinical trials.[20] Due to this status, those receiving Covaxin were required to sign a consent form,[21] while some states chose to relegate Covaxin to a "buffer stock" and primarily distribute Covishield.[22]

COVID-19 vaccination roll out in AIIMS, New Delhi, India on 16 January 2021

India began its vaccination programme on 16 January 2021, operating 3,006 vaccination centres on the onset.[23] Each vaccination centre will offer either Covishield or Covaxin, but not both.[24] 165,714 people were vaccinated on the first day of availability. Difficulties in uploading beneficiary lists at some sites caused delays.[25] In the first three days, 631,417 people were vaccinated. Of these, 0.18% reported side-effects and nine people (0.002%) were admitted to hospitals for observation and treatment.[26][27] Within those first days, there were concerns about low turnout, due to a combination of vaccine safety concerns, technical problems with the software used, and misinformation.[28]

The first phase of the rollout involved health workers and frontline workers, including police, paramilitary forces, sanitation workers, and disaster management volunteers.[23] By 1 March, only 14 million healthcare and frontline workers had been vaccinated, falling short of the original goal of 30 million.[29]

Second phase[edit]

The next phase of the vaccine rollout covered all residents over the age of 60, residents between the ages of 45 and 60 with one or more qualifying comorbidities, and any health care or frontline worker that did not receive a dose during phase 1. Online registration began on 1 March via the Aarogya Setu app and Co-WIN ("Winning over COVID-19") website.[30][31][32] Amid the beginnings of a major second wave of infections in the country,[33][34][35] vaccine exports were suspended in March 2021, and the government ordered 110 million Covishield doses from SII.[36] The company aims to produce 100 million doses per month, but by May 2021 its production capacity was only 60–70 million doses.[37][38] Following the conclusion of its trial, the DCGI issued a standard emergency use authorisation to Covaxin on 11 March 2021.[39]

From 1 April, eligibility was extended to all residents over the age of 45.[40] On 8 April, Prime Minister Narendra Modi called for a four-day Teeka Utsav ("Vaccine Festival") from 11 to 14 April, with a goal to increase the pace of the program by vaccinating as many eligible residents as possible. By the end of the Utsav, India had reached a total of over 111 million vaccine doses to-date.[41][42][43]

Third phase, Sputnik V approval[edit]

On 12 April, the DCGI approved Russia's Sputnik V vaccine for emergency use in India. A phase 3 trial was conducted in the country in September 2020, which showed 91.6% efficacy.[44] The local distributor Dr. Reddy's Laboratories stated that it planned to have the vaccine in India by late May 2021.[45]

On 19 April, it was announced that the next phase of the vaccination programme would begin on 1 May, extending eligibility to all residents over the age of 18. Under phase 3, individual stakeholders were also given more flexibility in how they conduct the vaccination programme. As part of this plan, only half of the vaccines procured by the Central Drugs Laboratory from manufacturers would be distributed by the central government. This supply would go to government-run clinics and be offered free-of-charge to residents 45 and over and priority workers and siphoned off to states based on factors such as the number of active cases and how quickly they are administering vaccines. The remainder would be offered to individual states and purchased on the open market (including private hospitals), which would be able to serve residents over the age of 18.[46][47][48]

Registration for the next phase began on 28 April; a single-day record of nearly 13.3 million people registered.[49] Due to supply issues, several states, including Delhi, Gujarat and Madhya Pradesh announced that they would delay their wider rollouts of vaccines to later in the month.[50]

The initial shipment of 150,000 Sputnik V doses arrived on 1 May, and began to be administered on 14 May.[51][52][53] An estimated 156 million doses is expected between August and December; initially, doses will be sourced from Russia, but domestic production is expected to begin by August 2021.[54][55][56]

On 13 May, the DCGI approved phase 2 and phase 3 trials of Covaxin on children 2–18.[57] On 14 May, health officials projected that based on the anticipated approval of additional vaccine options, it could receive at least 2.17 billion more vaccine doses from August to December 2021.[58][59] On 25 May, India exceeded 200 million vaccine doses administered in total.[60] On 3 June, the Ministry of Health and Family Welfare pre-ordered 300 million doses of a potential fourth vaccine, Corbevax, which is undergoing phase 3 clinical trials.[61]

On 23 May, the union government allowed walk-in registrations for vaccination throughout the country; a health worker at the vaccination centre would register the recipient in the Co-win vaccination database. The government claimed in an affidavit to the Supreme Court that as of June 23 about 78 per cent of vaccines had been administered via walk-in registration.[62]

Return to centralised procurement[edit]

On 31 May, an affidavit was issued in the Supreme Court of India requesting a review of the central government's vaccine distribution strategy, suggesting that the decision to only offer doses at no charge to priority workers and residents over the age of 45 was "prima facie arbitrary and irrational".[63]

On 7 June, Prime Minister Modi announced that India would migrate back to centralised procurement of vaccines by 21 June. In an address, Modi stated that multiple chief ministers had requested that the central government reconsider its new distribution strategy and reinstate the system it had used before May. As before, the centre will procure up to 75% of the country's vaccine supplies from manufacturers in bulk and distribute them to states at no additional charge. Vaccines would now be offered at no charge for those in the 18–44 age group. Private hospitals will still be responsible for the remaining 25% of procurement, but fees for appointments are now capped at ₹150 (US$2.10).[64][65]

On 21 June, the day these changes took effect, approximately 8,270,000 doses were administered—India's largest single-day total until that point. The states of Madhya Pradesh and Karnataka had the highest local totals.[66][67][68] Member of Parliament, Rajya Sabha P. Chidambaram accused Bharatiya Janata Party of having "hoarded" vaccine doses in the days leading up to 21 June in order to encourage larger numbers; seven states controlled by the BJP were among the top ten states to have administered vaccine doses that day, few of these states had below-average vaccination numbers in the days leading up to 21 June (such as Madhya Pradesh, which went from 692 doses on 20 June to 1,690,000 the next day, and numbers had dropped significantly in the state the next day).[69][70][71][72]

On 23 June, India surpassed over 300 million vaccine doses administered in total.[73] On 28 June, India overtook the United States in total vaccine doses administered.[74] On 29 June, the DCGI approved the Moderna vaccine (which is being imported by Cipla) for emergency use. Vinod Kumar Paul stated that the Pfizer vaccine was also likely to be approved soon.[75][76]

500 million mark, Johnson & Johnson Covid-19 vaccine approval and record[edit]

On 6 August 2021, India crossed the 500 million doses milestone within 6 months from the onset of the vaccination program.[77]

On 7 August 2021, the Drug Controller General of India (DCGI) approved emergency use of the Johnson and Johnson single-dose vaccine.[78] On 16 Aug 2021, India administered around 8.81 million doses of COVID-19 vaccines, achieving the highest single-day record and overtaking its own previous record of 8.61 million doses, by 16 August the cumulative doses had surpassed the 55 million mark.[79][80]

ZyCoV-D approval for ages 12 & above and single day vaccination records[edit]

On 20 August 2021, India granted emergency use approval to the world's first DNA based COVID-19 vaccine, ZyCoV-D manufactured by Zydus Cadila for adults and children aged 12 years and above. The vaccine is administered using a needle-free applicator.[81][82] The government announced on 30 September 2021 that the ZyCoV-D vaccine will be a three dose vaccine and it will be included in the Covid vaccination programme of India.[83]

Since August 10, 2021, foreign nationals residing in India can now receive the COVID-19 vaccine by registering themselves on the Cowin platform; like other eligible beneficiaries, the foreign nationals can book a slot via the portal and use their passport as a document to verify their identity for the registration process.[84]

By 26 August 2021, 50% of the adult population in India were inoculated with at least one dose of the approved vaccines, which included 99% coverage among healthcare workers and 100% front-line workers for the first dose.[85]

On 27 August 2021, India crossed the milestone of administering more than 10 million (1 crore) doses of COVID-19 vaccine in a single day, setting a new world record. Uttar Pradesh topped the list with 2.8 million doses, followed by Karnataka with 1 million doses and Maharashtra at third with 0.98 million doses.[86]

On 29 August 2021, Himachal Pradesh became the first state to complete administering first doses of COVID-19 vaccines to 100% of the population.[87] On 31 August, India again set another single-day vaccination record by inoculating around 12 million (1.2 Crore) doses in 24 hours.[88]

By September 2021, all adult people in Sikkim, Dadra and Nagar Haveli, Himachal Pradesh, Goa, Ladakh, and Lakshadweep have received at least one dose of Covid vaccine as the cumulative jabs administered in the country crossed 75 crores. Many city corporations, talukas, gram panchayats and districts had also administered the first dose of COVID-19 vaccination to 100 per cent of their adult population.[89][90] [91]

As many as 25 million people were vaccinated on Narendra Modi's birthday on 17 September 2021. This is the highest single-day vaccination tally so far in the whole world.[92] There are allegations that a lot of pressure could have been put on officials to increase and twist to record vaccination numbers on the Prime Minister's birthday as some people who had not received their Covid shots somehow seem to have been issued vaccination certificates including those who are deceased.[93][94]

On 27 September, India administered over 1 crore vaccine doses for the fifth time, and total vaccination coverage crossed 86 crore (860 million).[95]

On 2 October, Union health minister Mansukh Mandaviya announced that India crossed the landmark of administrating 90 crore vaccine doses.[96]

1 billion mark, vaccine clinical trial for children aged 7-11 and government's view on booster shots[edit]

The Government and India's drug regulator allowed vaccine manufacturer, Serum Institute on 28 September 2021 to enroll children between seven and 11 years of age for its COVID-19 vaccine trial.[97]

The conversation around the booster doses of COVID-19 vaccines gained momentum after people in many western countries were inoculated with the booster dose, or the third dose. The debate is raging in India where a major chunk of the eligible population has already been inoculated with at least one dose since the beginning of the Covid vaccination drive in January. The Indian government has, by far, maintained that booster shots of Covid vaccines and the benefit they provide are under purview and study, the current focus should be on ensuring two doses for every adult in the country.[98]

On 21 October 2021, India crossed the one billion mark for administered doses.[99]

Booster dose and vaccination for youths[edit]

India will start giving booster shots from January 10, 2022, to health and frontline workers and those over 60 with comorbidities or other health problems - Prime Minister Narendra Modi announced. He also said vaccinations will begin for youths between 15 and 18 years from January 3, 2022.[100] Among healthcare and frontline workers and those aged 60 and above with comorbidities, prioritisation and sequencing would be based on completion of nine months or 39 weeks from the date of the second dose as of January 10, the government said in its guidelines. Youths between 15 and 18 years can register online on CoWin from January 1, 2022, or onsite at vaccination centres from January 3, 2022. Covaxin is the only covid vaccine available for citizens between 15 and 18.[101]

Vaccine development and distribution[edit]

Prime Minister Narendra Modi visiting the Serum Institute of India on 28 November 2020.

As of early May 2020, there were over 30 vaccine candidates in development in India, many of which were already in pre-clinical trials.[102]

The Pune-based Serum Institute of India (SII) is the world's largest vaccine maker. This existing capacity enabled India to be a major participant in the COVAX programme to distribute vaccines to developing countries.[103] In February 2020, SII had begun animal trials of vaccine candidates.[104] SII announced in April 2020 that it would apply for clinical trials from the Drug Controller General of India (DCGI) in April 2020. SII president Adar Poonawalla said that a vaccine would be delivered within a year, but projected an efficacy between 70 and 80%.[105]

In August 2020, SII received approvals for phase 2 and phase 3 trials of its version of a vaccine being developed by AstraZeneca and the University of Oxford's Vaccitech.[106] SII joined GAVI in a partnership with the Bill & Melinda Gates Foundation to produce 100 million doses of vaccine for developing countries.[107] The SII planned to manufacture 1.5 and 2.5 billion doses of the AstraZeneca vaccine per-year under the trade name "Covishield".[108] By its approval in January 2021, the company had stockpiled 50 million doses, but well short of its own target of 400 million.[109][110] The government ordered 21 million doses to be delivered by February, but the company said no indication of any further orders were given.[36] The company began to export the remaining stocks instead.[108]

Hyderabad-based Bharat Biotech, in collaboration with U.S.-based FluGen, expected to begin the first clinical trials of a nasal vaccine by late-2020.[111] The Indian Council of Medical Research partnered with Bharat Biotech in May 2020 to develop a COVID vaccine entirely within India.[112] In June 2020, it received DCGI approval to begin phase 1 and phase 2 trials on its vaccine, BBV152 (trade name "Covaxin").[113] In September 2020, it was reported that in pre-clinical trials on animals, Covaxin was able to build immunity.[114] In July 2021, Bharat Biotech reported the vaccine to be Template:Estimate effective against asymptomatic cases, Template:Estimate effective against symptomatic cases, Template:Estimate effective against severe COVID-19 infection, and Template:Estimate effective against the Delta variant.[115][116] On 20 April 2021, Bharat Biotech announced that it had expanded its production capabilities for Covaxin to 700 million doses per-year.[117]

Cadila Healthcare began vaccine development in March 2020, including a viral vector vaccine and a DNA plasmid vaccine.[118][119] In mid-July 2020, Cadila held early human trials of its vaccine candidate ZyCoV-D,[120] and received approval for phase 3 trials in January 2021.[121][122] It began large-scale production in April 2021, with Cadila expecting to receive emergency authorisation between May and June 2021.[123] On 1 July 2021, Cadila Healthcare reported the efficacy to be 66.6% against symptomatic COVID-19 and 100% against moderate or severe disease in its interim analysis of its phase 3 trial data.[124][125]

In September 2020, Dr. Reddy's partnered with the Russian Direct Investment Fund (RDIF) to conduct phase 3 trials of the Sputnik V vaccine in India, and to distribute the vaccine there once approved.[126][127] In April 2021, RDIF CEO Kirill Dmitriev told NDTV that they had "five great manufacturers in India" who would be producing the vaccine, and felt that the country could become Sputnik V's "production hub" for use and export.[128] Dr. Reddy's is also working with the RDIF on approval of "Sputnik Light"—a regiment of Sputnik V consisting only of the first dose.[56]

In April 2021, phase 3 clinical trials were approved for another vaccine, Corbevax, a protein subunit that is being developed by BioE, the Baylor College of Medicine, and Dynavax Technologies.[61][129]

On 2 June 2021, the DCGI removed the requirement that India-specific clinical trials (bridging trials) be held for vaccine candidates developed outside of India, provided that they are already approved by a recognised international public health agency such as the World Health Organization (WHO), European Medicines Agency (EMA), US Food and Drug Administration (FDA), UK Medicines and Healthcare products Regulatory Agency (MHRA), or Japan's Pharmaceuticals and Medical Devices Agency. These changes were intended to help expedite the availability of vaccines already in use in other countries.[75][130]

In mid-July, it was reported that approval of the Moderna and Pfizer vaccines, as well as a shipment of vaccines donated by the United States (which includes the AstraZeneca, Janssen, Moderna, and Pfizer vaccines), had faced delays due to requests from their manufacturers for indemnity clauses from Indian authorities, which would relieve them from legal liability for adverse reactions.[131][132]

On 21 September 2021, the Indian Government said that it will not purchase the Pfizer-BioNTech and Moderna vaccines as domestic output of more affordable and easier-to-store vaccines has jumped.[133]

In the Quad summit, Prime Minister Narendra Modi announced that India would make 8 million doses of J&J vaccine available by the end of October under the Quad vaccine partnership. It will be manufactured in India by the Biological E. This would be ready by the end of October, compatible with our decision to resume vaccine export.[134]

On 6 February 2022, DCGI approved sputnik light covid vaccine for emergency use in India.[135]

Vaccine deployment strategies[edit]

Optimizing vaccination deployment for India[136] includes tailoring of strategies to the demographic and epidemiologic situation by modeling vaccination scenarios,[137] explore measures to reach children at risk[138] and co-optimizing vaccination strategy for societal and individual benefit in parallel.[139]

Vaccine on order[edit]

Vaccine Status Production Capacity Planned Capacity Doses ordered Approval Deployment
Covishield Green check.svg In use 840 million [140] - 750 million [141][142] Green check.svg 01 January 2021[143] Green check.svg 16 January 2021[144]
Covaxin Green check.svg In use 700 million [145] - 550 million [141] Green check.svg 03 January 2021[146] Green check.svg 16 January 2021[144]
Sputnik V Green check.svg In use 140 million - 156 million [147][141] Green check.svg 12 April 2021[44] Green check.svg 14 May 2021[148]
Corbevax Green check.svg In use - 960 million [149] 300 million [150] Green check.svg 28 December 2021[151] Green check.svg 16 March 2022[152]
Moderna Green check.svg Approved Import only[153] - - Green check.svg 29 June 2021[154] Dark Red x.svg Order Cancelled[155]
Johnson & Johnson Green check.svg Approved - 8 million[134] - Green check.svg 7 Aug 2021 [156] Dark Red x.svg Not yet[134]
ZyCoV-D Green check.svg Approved - 240 million [157] 10 million[158] Green check.svg 20 August 2021[159] Dark Red x.svg Not yet
Covovax Green check.svg Approved - - 200 million [141] Green check.svg 28 December 2021[151] Dark Red x.svg Not yet
Sputnik Light Green check.svg Approved - - - Green check.svg 6 February 2022[135] Dark Red x.svg Not yet

In September 2021, India's government announced that it would not buy COVID-19 shots from Pfizer (PFE.N)/BioNTech (22UAy.DE) and Moderna (MRNA.O), mainly because the domestic output of more affordable and easier-to-store vaccines of Serum Institute of India, Bharat Biotech & Cadila Healthcare has jumped. India will make 8 million doses of the Johnson and Johnson vaccine available by the end of October under the Quad vaccine partnership.[134][152]

Vaccines in trial stage[edit]

Vaccine Type (technology) Phase I Phase II Phase III No. of Participants in Clinical Trial Planned Capacity
BBV154 Adenovirus vector (intranasal) Green check.svg Completed In progress Pending 175[160][161] 100 million[141]
HGC019 mRNA Green check.svg Completed In progress Pending 120 [162] 60 million [141]

Vaccine Maitri[edit]

Main article: Vaccine Maitri

Vaccine Maitri (English: Vaccine Friendship)[163] is a humanitarian initiative undertaken by the Indian government to provide COVID-19 vaccines to countries around the world.[164] The government started providing vaccines from 20 January 2021. As of 6Template:NbsMarch 2022, India had delivered around 16.3 cror doses of vaccines to 96 countries.[165] Of these, 1.43 cror doses were gifted to 46 countries by the Government of India. The remaining 10.71 cror were supplied by the vaccine producer under its commercial and, 4.15 cror doses were supplied throw COVAX obligations. In late March 2021, the Government of India temporarily froze exports of the Covishield, citing India's own COVID crisis and the domestic need for these vaccines.[166] The Health Minister of India, Mr. Mansukh Mandaviya announced in September that India will resume the export of vaccines from October to the rest of the world.[167][168]

Oxford AstraZeneca COVID-19 vaccine (Indian version) 2021 L.jpeg
Countries that received doses of the Indian-made Covaxin as of 6Template:NbsMarch 2021

200,000 doses of COVID-19 vaccines were gifted by India to the UN peacekeepers on 27 March to be distributed to all peacekeeping missions.[169]

Vaccines[edit]

India has two approved COVID-19 vaccines: Covishield and Covaxin. Both of them were exported and used in foreign grants by the Government of India.

Covishield[edit]

Main article: Oxford–AstraZeneca COVID-19 vaccine
A vial of Covishield, the Indian-manufactured version of the AstraZeneca vaccine.

On 1 January 2021, the Drug Controller General of India, approved the emergency or conditional use of Covishield.[170] Covishield is developed by the University of Oxford and its spin-out company, Vaccitech.[171]

Covaxin[edit]

Main article: Covaxin
A vial of Covaxin, India's first indigenous COVID-19 vaccine by Bharat Biotech

On 2 January 2021, Covaxin India's first COVID-19 vaccine, developed by Bharat Biotech in association with the Indian Council of Medical Research and National Institute of Virology received approval from the Drug Controller General of India for its emergency or conditional usage.[172]

Vaccine supply[edit]

India kicked off international shipment of the vaccines on 20 January 2021, only four days after starting its own vaccination program.[173] Bhutan and Maldives were the first countries to receive vaccines as a grant by India. This was quickly followed by shipments to Nepal, Bangladesh, Myanmar and Seychelles.[173] By mid-March 2021, India was also supplying vaccines on a commercial basis to countries including Canada,[174] the UK,[175] and Saudi Arabia.[176]

As of 21 February 2022, India had exported total 16,29,63,500 doses including 1,42,67,000 vaccine provided as grant to more than 96 nations and, UN Peacekeepers and UN Health workers.[165]

The Serum Institute of India was selected as a key supplier of cost-effective COVID-19 vaccines to the COVAX initiative,[177] 19.8 million doses of Covishield vaccines were supplied by India to various countries through the initiative.[165] In May, when COVAX was already short 140 million doses,[178] the Serum Institute announced that it expected to maintain its suspension of vaccine deliveries to COVAX through the end of 2021[179] due to the second wave of COVID-19 in India[180] and the US ban on export of key raw materials.[181]

International reaction[edit]

International organizations[edit]

  • IMF: IMF chief economist Gita Gopinath lauded India for playing a key role during the crisis by dispatching vaccines to many countries. She said "I also want to mention that India really stands out in terms of its vaccine policy. If you look at where exactly is one manufacturing hub for vaccines in the world – that will be India."[182]

Countries[edit]

  •  Jamaica[183] of the OACPS has thanked Indian efforts in delivering vaccines to developing and least developed countries.
  •    Nepal Prime minister Khadga Prasad Oli thanked India stating; "We got an early chance to administer the Covid-19 vaccine. For this, I thank our neighbouring nation India, its government, the people, and especially Prime Minister Narendra Modi. They sent 10 lakh doses of vaccines to us as a grant within a week of the roll-out in India."[184]
  • Template:Country data St. Lucia on behalf of CARICOM thanked India for providing vaccine supplies to them.[183][185]
  •  Barbados Prime Minister Mia Amor Mottley thanked Prime Minister Narendra Modi for the supply of "Made in India" COVID-19 vaccines. She tweeted, "PM Modi made it possible for more than 40,000 persons in Barbados and tens of thousands elsewhere, to receive their 1st dose of COVISHIELD via Vaccine Maitri before receiving his. A genuine demonstration of generosity. Thank you and we wish you continued good health."[186]
  •  Antigua and Barbuda Prime Minister Gaston Browne had thanked Prime Minister of India Narendra Modi "for demonstrating an act of benevolence, kindness and empathy", for sending vaccines to Caribbean countries.[187]
  •  Afghanistan Afghanistan's ambassador to India Farid Mamundzay said "Thank you, India for providing Afghan people lifesaving gift on the first day of 2022!"[188]

Leaders who received vaccines provided by India[edit]

Gallery[edit]

  • COVID-19 vaccine from India arrives at Seychelles.

    COVID-19 vaccine from India arrives at Seychelles.

  • Delivery of Covishield COVID-19 vaccine from India to Brazil.

    Delivery of Covishield COVID-19 vaccine from India to Brazil.

  • Delivery of Covishield COVID-19 vaccine from India to Brazil.

    Delivery of Covishield COVID-19 vaccine from India to Brazil.

  • Vaccination drive for COVID prevention in Bhopal, India.

    Vaccination drive for COVID prevention in Bhopal, India.

Vaccination rollout statistics by State or UT[edit]

State/union territory Population (2021 census projection) 1st dose 2nd dose Precautionary/ Booster Dose Cumulative doses administered Percentage of people given one dose Percentage of people fully vaccinated
India 1,38,94,19,783 1,01,25,58,641 90,40,31,986 4,01,46,387 1,95,67,37,014 73% 65%
Andaman and Nicobar Islands 4,00,000 3,43,506 3,40,811 26,407 7,10,724 86% 85%
Andhra Pradesh 5,27,87,000 4,46,28,554 4,74,81,050 42,14,776 9,63,24,380 85% 90%
Arunachal Pradesh 15,33,000 9,18,081 7,70,753 35,195 17,24,029 60% 50%
Assam 3,50,43,000 2,44,63,545 2,10,98,119 5,72,466 4,61,34,130 70% 60%
Bihar 12,30,83,000 7,09,68,816 6,07,99,671 23,87,222 13,41,55,709 58% 49%
Chandigarh 12,08,000 11,76,946 9,61,527 50,615 21,89,088 97% 80%
Chhattisgarh 2,94,93,000 2,06,98,184 1,84,71,001 5,95,922 3,97,65,107 70% 63%
Dadra and Nagar Haveli 6,08,000 4,58,121 3,46,904 10,213 8,15,238 75% 57%
Daman and Diu 4,09,000 3,18,849 2,75,911 10,700 6,05,460 78% 67%
Delhi 2,05,71,000 1,80,93,817 1,52,00,377 13,20,306 3,46,14,500 88% 74%
Goa 15,59,000 14,34,149 12,81,932 59,419 27,75,500 92% 82%
Gujarat 6,97,88,000 5,40,09,388 5,29,59,290 36,74,816 11,06,43,494 77% 76%
Haryana 2,94,83,000 2,35,54,505 1,93,50,790 8,25,832 4,37,31,127 80% 66%
Himachal Pradesh 73,94,000 65,98,001 62,12,138 3,80,736 1,31,90,875 89% 84%
Jammu and Kashmir 1,34,08,000 1,13,16,227 1,13,90,693 4,50,867 2,31,57,787 84% 85%
Jharkhand 3,84,71,000 2,34,27,973 1,65,87,053 3,86,223 4,04,01,249 61% 43%
Karnataka 6,68,45,000 5,46,64,593 5,31,16,037 28,56,475 11,06,37,105 82% 79%
Kerala 3,54,89,000 2,88,60,790 2,46,94,647 18,92,337 5,54,47,774 81% 70%
Ladakh 2,97,000 2,37,187 1,99,965 71,069 5,08,221 80% 67%
Lakshadweep 68,000 61,481 58,786 4,150 1,24,417 90% 86%
Madhya Pradesh 8,45,16,000 6,03,94,658 5,77,67,097 15,75,704 11,97,37,459 71% 68%
Maharashtra 12,44,37,000 9,06,60,320 7,41,50,393 32,80,617 16,80,91,330 73% 60%
Manipur 31,65,000 15,83,386 12,46,921 1,02,770 29,33,077 50% 39%
Meghalaya 32,88,000 14,25,886 10,57,028 46,084 25,28,998 43% 32%
Mizoram 12,16,000 8,78,536 7,11,158 48,532 16,38,226 72% 58%
Nagaland 21,92,000 9,12,550 7,24,408 33,829 16,70,787 42% 33%
Odisha 4,56,96,000 3,47,93,995 3,15,83,796 15,00,574 6,78,78,365 76% 69%
Puducherry 15,71,000 9,69,574 7,29,374 27,271 17,26,219 62% 46%
Punjab 3,03,39,000 2,39,03,346 1,96,94,650 6,90,578 4,42,88,574 79% 65%
Rajasthan 7,92,81,000 5,64,48,182 4,86,39,892 20,30,239 10,71,18,313 71% 61%
Sikkim 6,77,000 5,86,991 5,43,380 38,760 11,69,131 87% 80%
Tamil Nadu 7,64,02,000 5,93,56,840 5,16,45,101 11,94,734 11,21,96,675 78% 68%
Telangana 3,77,25,000 3,22,18,136 3,06,90,601 8,97,738 6,38,06,475 85% 81%
Tripura 40,71,000 28,81,012 24,28,446 1,40,823 54,50,281 71% 60%
Uttar Pradesh 23,09,07,000 17,50,48,912 15,61,43,484 33,57,825 33,45,50,221 76% 68%
Uttarakhand 1,13,99,000 90,38,655 84,61,743 6,38,901 1,81,39,299 79% 74%
West Bengal 9,81,25,000 7,29,82,439 6,46,38,638 32,83,807 14,09,04,884 74% 66%
Miscellaneous — 22,42,510 15,78,421 14,31,855 52,52,786 — —
As of June 17, 2022 7:00 AM IST[191]

As of June 17, 2022, populations above the age of 12 are only eligible for vaccination. The percentage of population inoculated shown in the table above is according to the 2021 projected population of India with all age groups. According to the government, based on the projected mid-year count for 2021, the country's total population aged 12 years and above is approximately 108 crore. Around 93.39% of the 12+ population of the country have received at least one dose of the COVID-19 vaccine since the vaccination drive began. In addition to this, 83.38% of the eligible population has been fully vaccinated.[192]

Vaccine acceptance in India[edit]

Over 80% of the population of India have a positive response for getting anti covid shots. India has one of the lowest vaccine hesitancy in the world.[193] There was vaccine hesitancy in the initial months of 2021, especially in rural India and among poor and tribal populations. Constant government and public awareness drastically reduced vaccine hesitancy. Since May 2021, more than half of daily doses administered in India have been from rural parts.[194] Vaccine centers in India have witnessed large number of people willing to get covid vaccine resulting in overcrowding and mismanagement. Many centers across India in months of April & May reported severe shortage of covid vaccines due to large crowds turning up for vaccination. In cities like Mumbai, New Delhi, Bengaluru many people even after waiting for hours did not receive their covid vaccine due to shortage.[195] Since July, vaccine supply has drastically increased thus India is vaccinating at a very fast pace.[196]

One study published on vaccine acceptance shows that 79.5% of people from Delhi want to take a COVID-19 vaccine.[197] In another study which was published from West Bengal, a state in Eastern India, has shown that 77.27% of people want to take the COVID-19 vaccine.[198] According to the finding from these two studies, it can be expected that over 75% of people want to get a COVID-19 vaccine.

Adverse events[edit]

Like many other vaccinations, COVID-19 vaccines also have a risk of causing side effects. According to India's Union Ministry of Health and Family Welfare, the most common side-effects include pain or swelling at the injection site, fever, irritability and headaches.[199] The UK Government also lists fatigue, nausea and joint pain as common side-effects of the Oxford vaccine (known as Covishield in India).[200] Medical experts maintain that vaccines used are safe and their benefits outweigh the risks. It is also important to note that adverse cases do not necessarily have a causal relationship with the vaccines.[201]

A total of 617 serious adverse events were reported until March 29. Of these, 180 cases resulted in death. The Immunisation Technical Support Unit at the federal health ministry examined 192,000 case reports, including 12,400 deaths. In more than half of the examined cases of death, the cause of death was found to be acute coronary syndrome. However, the documentation had been completed for only 3,500 cases.[202]

By 7 June, 26,000 adverse events had been reported following immunisation. Of this, 24,901 were minor, 412 were significant and 887 were serious. 488 deaths were also reported, including 301 men and 178 women (details of 9 deaths were not available). Both vaccines had an adverse reaction rate of about 0.01% and a fatality rate of around 0.0001% - 24,703 events and 457 deaths from 210 million Covishield doses, 1,497 events and 20 deaths following 25 million Covaxin doses. Maharashtra reported the most adverse events (4,521), followed by Kerala (4,074), Karnataka (2,650) and West Bengal (1,456).[201][203]

On 15 June, the government published a review of case reports that had occurred between 5 February and 31 March 2021, focusing on 31 cases and one death from anaphylaxis that were believed to have been attributed to the vaccine, out of nearly 60 million doses administered in the time period. Only three of these cases, and the single death of a 68-year-old patient, were determined to be "vaccine-product related", with the remainder having been classified as coincidental, indeterminate, or unclassifiable. The report stated that "mere reporting of deaths and hospitalisations as serious adverse events does not automatically imply that the events were caused due to vaccines. Only properly conducted investigations and causality assessments can help in understanding if any causal relationship exists between the event and the vaccine."[204][205][206]

References[edit]

Footnote references[edit]

  1. ↑ All government run vaccination centers provide free of cost vaccines
  2. ↑ Vaccination Centres/facilities charge as per dose

Web References[edit]

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Notes[edit]

  1. ↑ Moderna, Johnson & Johnson and Zydus Cadila are not yet under distribution
  2. ↑ Zydus Cadila is the only vaccine to been approved for children above 12 years

External links[edit]

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