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{{Short description|Indian structural biologist}}
{{Use dmy dates|date=March 2019}}
{{Use dmy dates|date=March 2019}}
{{Use Indian English|date=March 2019}}
{{Use Indian English|date=March 2019}}
{{Infobox scientist
{{Infobox scientist
| name = Arun Kumar Shukla
| name             = Arun Kumar Shukla
| image =  
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| birth_date =  
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| birth_place = [[Kushinagar]], [[Uttar Pradesh]], India
| birth_place       = [[Kushinagar]], [[Uttar Pradesh]], India
| death_date =  
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| death_place =  
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| residence = [[Kanpur]], [[Uttar Pradesh]], India
| fields           = {{ublist | [[Structural biology]] }}
| nationality = [[Indian nationality|Indian]]
| workplaces       = {{ublist | [[Duke University]] | [[Indian Institute of Technology, Kanpur]] }}
| fields = {{ublist | [[Structural biology]] }}
| alma_mater       = {{ublist|[[Jawaharlal Nehru University]] | [[Max Planck Institute of Biophysics|Max Planck Institute]]|[[Duke University]] | [[Stanford University]] }}
| workplaces = {{ublist | [[Duke University]] | [[Indian Institute of Technology, Kanpur]] }}
| doctoral_advisor = {{ublist|[[Hartmut Michel]] | [[Robert J. Lefkowitz]] | [[Brian Kobilka]]}}
| alma_mater = {{ublist|[[Jawaharlal Nehru University]] | [[Max Planck Institute of Biophysics|Max Planck Institute]]|[[Duke University]] | [[Stanford University]] }}
| doctoral_advisor = {{ublist|[[Hartmut Michel]] | [[Robert J. Lefkowitz]] | [[Brian Kobilka]]}}
| doctoral_students =  
| doctoral_students =  
| known_for = Studies on [[G protein-coupled receptor]]
| known_for         = Studies on [[G protein-coupled receptor]]
| awards = {{ublist| 2017 B. M. Birla Science Prize | 2016 [[National Academy of Sciences, India|NASI]]-Young Scientist Platinum Jubilee Award | 2017 EMBO Young Investigator Award | 2017/18 [[National Bioscience Award for Career Development|N-BIOS Prize]] | 2018 [[Indian Council for Medical Research|ICMR]] Shakuntala Amir Chand Prize | 2018 [[Central Drug Research Institute|CDRI]] Award}}
| awards           = {{ublist| 2025 [[Fellow, TWAS]] in Biological Sciences | 2024 [[OPPI Scientist of the Year Award]] |2023  [[Infosys Prize]] in Life Sciences |2022 Fellow, [[Indian National Science Academy]] | 2021 [[Fellowship, Indian Academy of Sciences]] | 2021 [[Khosla National Award of IIT Roorkee]] | 2021 [[Fellowship, National Academy of Sciences]] | 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]]| 2019 [[Rajib Goyal Prize by Kurukshetra University]]| 2017 B. M. Birla Science Prize | 2016 [[National Academy of Sciences, India|NASI]]-Young Scientist Platinum Jubilee Award | 2017 EMBO Young Investigator Award | 2017/18 [[National Bioscience Award for Career Development|N-BIOS Prize]] | 2018 [[Indian Council for Medical Research|ICMR]] Shakuntala Amir Chand Prize | 2018 [[Central Drug Research Institute|CDRI]] Award}}
}}
}}
'''Arun Kumar Shukla''' is an Indian structural biologist and the Joy-Gill Chair professor at the department of biological sciences and bioengineering at the [[Indian Institute of Technology, Kanpur]].<ref name="Arun K. Shukla IITK">{{Cite web |url=https://www.iitk.ac.in/bsbe/arun-k-shukla |title=Arun K. Shukla IITK |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}}</ref> Known for his studies on [[G protein-coupled receptor]], Shukla is a [[Wellcome Trust]]-[[Department of Biotechnology|DBT]] Intermediate Fellow and a recipient of the SwarnaJayanti Fellowship of the [[Department of Science and Technology (India)|Department of Science and Technology]].<ref name="List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18">{{Cite web |url=http://www.dst.gov.in/sites/default/files/Final-List-SwarnaJayanti-Fellows-2017-18.pdf |title=List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18 |date=2018-12-30 |website=Department of Science and Technology |access-date=2018-12-30}}</ref> The [[Department of Biotechnology]] of the Government of India awarded him the [[National Bioscience Award for Career Development]], one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.
'''Arun Kumar Shukla''' is an Indian structural biologist and the Joy-Gill Chair professor at the department of biological sciences and bioengineering at the [[Indian Institute of Technology, Kanpur]].<ref name="Arun K. Shukla IITK">{{Cite web |url=https://www.iitk.ac.in/bsbe/arun-k-shukla |title=Arun K. Shukla IITK |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}}</ref> Known for his studies on [[G protein-coupled receptor]], Shukla is a [[Wellcome Trust]]-[[Department of Biotechnology|DBT]] Intermediate Fellow and a recipient of the SwarnaJayanti Fellowship of the [[Department of Science and Technology (India)|Department of Science and Technology]].<ref name="List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18">{{Cite web |url=http://www.dst.gov.in/sites/default/files/Final-List-SwarnaJayanti-Fellows-2017-18.pdf |title=List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18 |date=2018-12-30 |website=Department of Science and Technology |access-date=2018-12-30}}</ref> The [[Department of Biotechnology]] of the Government of India awarded him the [[National Bioscience Award for Career Development]], one of the highest Indian science awards, for his contributions to biosciences, in 2017/18. He received the 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]] in [[Biological Science]].<ref name="sbprize">{{cite web |title=Shanti Swarup Bhatnagar Prize (SSB) for Science and Technology 2021 |url=https://ssbprize.gov.in/WriteReadData/LatestUpdates/202109260133259214500SSBPrize2021Website.pdf |website=sbprize.gov.in |publisher=[[Council of Scientific and Industrial Research]] |access-date=26 September 2021}}</ref> He was awarded the [https://www.infosysprize.org/laureates/2023/arun-shulka.html Infosys Prize 2023] in Life Sciences his outstanding contributions to the biology of G-protein coupled receptors (GPCRs).


==  Biography ==
==  Biography ==
[[File:A building at IIT Kanpur.jpg|thumb|left|IIT Kanpur]]
[[File:A building at IIT Kanpur.jpg|thumb|left|IIT Kanpur]]
Shukla, born in [[Kushinagar]] in the Indian state of [[Uttar Pradesh]],<ref name="Better pill">{{Cite web |url=https://www.telegraphindia.com/science/better-pill/cid/1377263 |title=Better pill |date=2018-12-30 |website=www.telegraphindia.com |language=en |access-date=2018-12-30}}</ref> earned his master's degree in biotechnology from [[Jawaharlal Nehru University]] after which he did his doctoral studies under the guidance of [[Hartmut Michel]] (Nobel Laureate, 1988) of [[Max Planck Institute of Biophysics]].<ref name="Arun K. Shukla IITK" /> His post-doctoral work was with [[Robert J. Lefkowitz]] (Nobel Laureate, 2012) of [[Duke University]] and [[Brian Kobilka]] (Nobel Laureate, 2012) of [[Stanford University]] and he started his career at Duke University as an assistant professor at their department of medicine. Returning to India, he joined the [[Indian Institute of Technology, Kanpur]] (IITK) at the Department of Biological Sciences and Bioengineering (BSBE)<ref name="BSBE People">{{Cite web |url=https://www.iitk.ac.in/bsbe/people |title=BSBE People |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}}</ref> where he holds the position of a professor<ref name="Arun Shukla on Samviti">{{Cite web |url=https://samviti.com/profile/arun-shukla-NzA4 |title=Arun Shukla on Samviti |date=2018-12-30 |website=samviti.com |language=en |access-date=2018-12-30}}</ref> and heads the ''Laboratory of GPCR Biology''.<ref name="Principal Investigator - Laboratory of GPCR Biology">{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/curriculum-vitae |title=Principal Investigator - Laboratory of GPCR Biology |date=2018-12-30 |website=sites.google.com |access-date=2018-12-30}}</ref>
Dr. Arun Kumar Shukla was born on 1 November 1981<ref>{{cite web |title=Arun Kumar Shukla Biography |url=https://nikhilbharat.com/arun-kumar-shukla-biography-in-hindi/ |website=Online Hindi world |date=27 November 2021}}</ref> in [[Kushinagar]] in the Indian state of [[Uttar Pradesh]],<ref name="Better pill">{{Cite web |url=https://www.telegraphindia.com/science-tech/better-pill/cid/1377263 |title=Better pill |date=2018-12-30 |website=www.telegraphindia.com |language=en |access-date=2018-12-30}}</ref> earned his master's degree in biotechnology from [[Jawaharlal Nehru University]] after which he did his doctoral studies under the guidance of [[Hartmut Michel]] (Nobel Laureate, 1988) of [[Max Planck Institute of Biophysics]].<ref name="Arun K. Shukla IITK" /> His post-doctoral work was with [[Robert J. Lefkowitz]] (Nobel Laureate, 2012) of [[Duke University]] and [[Brian Kobilka]] (Nobel Laureate, 2012) of [[Stanford University]] and he started his career at Duke University as an assistant professor at their department of medicine. Returning to India, he joined the [[Indian Institute of Technology, Kanpur]] (IITK) at the Department of Biological Sciences and Bioengineering (BSBE)<ref name="BSBE People">{{Cite web |url=https://www.iitk.ac.in/bsbe/people |title=BSBE People |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}}</ref> where he holds the position of a professor<ref name="Arun Shukla on Samviti">{{Cite web |url=https://samviti.com/profile/arun-shukla-NzA4 |title=Arun Shukla on Samviti |date=2018-12-30 |website=samviti.com |language=en |access-date=2018-12-30}}</ref> and heads the ''Laboratory of GPCR Biology''.<ref name="Principal Investigator - Laboratory of GPCR Biology">{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/curriculum-vitae |title=Principal Investigator - Laboratory of GPCR Biology |date=2018-12-30 |website=sites.google.com |access-date=2018-12-30}}</ref>


Shukla is known to have carried out extensive research on [[G protein-coupled receptor]] and his research is reported to have led to easier regulation of these receptors for better drug efficacy.<ref name="Drug discovery for GPCR signalling made easy by IIT Kanpur">{{Cite news |url=https://www.thehindu.com/sci-tech/Drug-discovery-for-GPCR-signalling-made-easy-by-IIT-Kanpur/article16973255.ece |title=Drug discovery for GPCR signalling made easy by IIT Kanpur |last=Prasad |first=R. |date=2017-01-01 |newspaper=The Hindu |language=en-IN |access-date=2018-12-30}}</ref> He led a team of IITK scientists who developed ''nanomachines'' which could be designed to ''selectively target signalling events inside living cells''.<ref name="IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells">{{Cite web |url=https://www.thehindubusinessline.com/news/science/iitkanpur-scientistled-team-designs-nanomachines-that-can-correct-anomalies-inside-living-cells/article9885557.ece |title=IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells |last=Jayan |first=T. V. |date=8 January 2018 |website=@businessline |language=en |access-date=2018-12-30}}</ref> The technique developed by them is in use with several drugs that are available in the market such as [[Telmisartan]], [[Olmesartan]], [[Fexofenadine]], [[Propanolol]], and [[Metoprolol]].<ref name="Better pill" /> He has published a number of articles and has contributed chapters to books published by others;<ref name="Research Publications - Laboratory of GPCR Biology">{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/publica |title=Research Publications - Laboratory of GPCR Biology |date=2018-12-31 |website=sites.google.com |access-date=2018-12-31}}</ref>{{Refn|group=note|Please see ''Selected bibliography'' section}} [[Google Scholar]], an online repository of scientific articles has listed 75 of them.<ref name="Arun K. Shukla - Google Scholar Citations">{{Cite web |url=https://scholar.google.co.in/citations?user=xIgDSCwAAAAJ&hl=en |title=Arun K. Shukla - Google Scholar Citations |date=2018-12-31 |website=scholar.google.co.in |access-date=2018-12-31}}</ref>
Shukla is known to have carried out extensive research on [[G protein-coupled receptor]] and his research is reported to have led to easier regulation of these receptors for better drug efficacy.<ref name="Drug discovery for GPCR signalling made easy by IIT Kanpur">{{Cite news |url=https://www.thehindu.com/sci-tech/Drug-discovery-for-GPCR-signalling-made-easy-by-IIT-Kanpur/article16973255.ece |title=Drug discovery for GPCR signalling made easy by IIT Kanpur |last=Prasad |first=R. |date=2017-01-01 |newspaper=The Hindu |language=en-IN |access-date=2018-12-30}}</ref> He led a team of IITK scientists who developed ''nanomachines'' which could be designed to ''selectively target signalling events inside living cells''.<ref name="IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells">{{Cite web |url=https://www.thehindubusinessline.com/news/science/iitkanpur-scientistled-team-designs-nanomachines-that-can-correct-anomalies-inside-living-cells/article9885557.ece |title=IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells |last=Jayan |first=T. V. |date=8 January 2018 |website=@businessline |language=en |access-date=2018-12-30}}</ref> The technique developed by them is in use with several drugs that are available in the market such as [[Telmisartan]], [[Olmesartan]], [[Fexofenadine]], [[Propranolol]], and [[Metoprolol]].<ref name="Better pill" /> He has published a number of articles and has contributed chapters to books published by others;<ref name="Research Publications - Laboratory of GPCR Biology">{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/publica |title=Research Publications - Laboratory of GPCR Biology |date=2018-12-31 |website=sites.google.com |access-date=2018-12-31}}</ref>{{Refn|group=note|Please see ''Selected bibliography'' section}} [[Google Scholar]], an online repository of scientific articles has listed 75 of them.<ref name="Arun K. Shukla - Google Scholar Citations">{{Cite web |url=https://scholar.google.co.in/citations?user=xIgDSCwAAAAJ&hl=en |title=Arun K. Shukla - Google Scholar Citations |date=2018-12-31 |website=scholar.google.co.in |access-date=2018-12-31}}</ref>


== Awards and honours ==
== Awards and honours ==
The [[Department of Biotechnology]] of the Government of India awarded him the [[National Bioscience Award for Career Development]], one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.<ref name="Awardees of National Bioscience Awards for Career Development">{{Cite web |url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |title=Awardees of National Bioscience Awards for Career Development |date=2016 |publisher=Department of Biotechnology |access-date=2017-11-20}}</ref> He has also received the B. M. Birla Science Prize (2017),<ref name="BM Birla Science Prize presented">{{Cite web |url=https://www.thehansindia.com/posts/index/Telangana/2018-01-29/BM-Birla-Science-Prize-presented/354957 |title=BM Birla Science Prize presented |date=2018-12-31 |website=www.thehansindia.com |access-date=2018-12-31}}</ref> NASI-Young Scientist Platinum Jubilee Award of the [[National Academy of Sciences, India]] (2016),<ref name="The National Academy of Sciences, India - Activities">{{Cite web |url=http://www.nasi.org.in/yspja.htm |title=The National Academy of Sciences, India - Activities |date=2018-12-31 |website=www.nasi.org.in |access-date=2018-12-31}}</ref> [[Central Drug Research Institute|CDRI]] Award (2018),<ref name="List of previous CDRI Awardees">{{Cite web |url=http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |title=List of previous CDRI Awardees |date=2018-12-31 |website=Central Drug Research Institute |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194121/http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |archive-date=31 December 2018 |url-status=dead }}</ref> Shakuntala Amir Chand Prize of the [[Indian Council for Medical Research]] (2018)<ref name="Awards - Indian Council of Medical Research">{{Cite web |url=https://www.icmr.gov.in/awards |title=Awards - Indian Council of Medical Research |date=2018-12-31 |website=ICMR |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194130/https://www.icmr.gov.in/awards |archive-date=31 December 2018 |url-status=dead }}</ref><ref name="News Archive">{{Cite web |url=https://www.iitk.ac.in/dofa/news-archive |title=News Archive |last=Vishwas |date=2018-12-31 |website=www.iitk.ac.in |language=en-gb |access-date=2018-12-31}}</ref> and the EMBO Young Investigator Award (2017).<ref name="IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator.">{{Cite web |url=https://www.pinterest.com/pin/155514993366608507/ |title=IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator |date=2018-12-30 |website=Pinterest |language=en |access-date=2018-12-30}}</ref>
Shukla received the [[Infosys Prize]] 2023 in Life Sciences, he was selected for this prestigious award by an eminent jury chaired by MIT Professor, [https://www.infosysprize.org/jury/life-sciences.html Mriganka Sur]. He received the 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]] in [[Biological Science]].<ref name="sbprize"/> The [[Department of Biotechnology]] of the Government of India awarded him the [[National Bioscience Award for Career Development]], one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.<ref name="Awardees of National Bioscience Awards for Career Development">{{Cite web |url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |title=Awardees of National Bioscience Awards for Career Development |date=2016 |publisher=Department of Biotechnology |access-date=2017-11-20 |archive-date=4 March 2018 |archive-url=https://web.archive.org/web/20180304191331/http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |url-status=dead }}</ref> He has also received the B. M. Birla Science Prize (2017),<ref name="BM Birla Science Prize presented">{{Cite web |url=https://www.thehansindia.com/posts/index/Telangana/2018-01-29/BM-Birla-Science-Prize-presented/354957 |title=BM Birla Science Prize presented |date=2018-12-31 |website=www.thehansindia.com |access-date=2018-12-31}}</ref> NASI-Young Scientist Platinum Jubilee Award of the [[National Academy of Sciences, India]] (2016),<ref name="The National Academy of Sciences, India - Activities">{{Cite web |url=http://www.nasi.org.in/yspja.htm |title=The National Academy of Sciences, India - Activities |date=2018-12-31 |website=www.nasi.org.in |access-date=2018-12-31 |archive-date=9 January 2019 |archive-url=https://web.archive.org/web/20190109212436/http://www.nasi.org.in/yspja.htm |url-status=dead }}</ref> [[Central Drug Research Institute|CDRI]] Award (2018),<ref name="List of previous CDRI Awardees">{{Cite web |url=http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |title=List of previous CDRI Awardees |date=2018-12-31 |website=Central Drug Research Institute |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194121/http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |archive-date=31 December 2018 |url-status=dead }}</ref> Shakuntala Amir Chand Prize of the [[Indian Council for Medical Research]] (2018)<ref name="Awards - Indian Council of Medical Research">{{Cite web |url=https://www.icmr.gov.in/awards |title=Awards - Indian Council of Medical Research |date=2018-12-31 |website=ICMR |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194130/https://www.icmr.gov.in/awards |archive-date=31 December 2018 |url-status=dead }}</ref><ref name="News Archive">{{Cite web |url=https://www.iitk.ac.in/dofa/news-archive |title=News Archive |last=Vishwas |date=2018-12-31 |website=www.iitk.ac.in |language=en-gb |access-date=2018-12-31}}</ref> and the EMBO Young Investigator Award (2017).<ref name="IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator.">{{Cite web |url=https://www.pinterest.com/pin/155514993366608507/ |title=IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator |date=2018-12-30 |website=Pinterest |language=en |access-date=2018-12-30}}</ref> He was elected as a fellow of the [[Indian National Science Academy]] in 2022.<ref name="INSA :: Indian Fellows Elected">{{Cite web |title=INSA :: Indian Fellows Elected |url=https://www.insaindia.res.in/ref3.php |access-date=2022-10-22 |website=www.insaindia.res.in}}</ref> In 2022 and 2024, Shukla was a laureate of the [[Asian Scientist 100]] by the ''[[Asian Scientist]]''.


== Selected bibliography ==
== Selected bibliography ==
* {{Cite journal |last=Ghosh |first=Eshan |last2=Nidhi |first2=Kumari |last3=Shukla |first3=Arun K. |date=2014 |title=SnapShot: GPCR-Ligand Interactions |journal=Cell |volume=159 |issue=7 |pages=1712–1712.e1 |doi=10.1016/j.cell.2014.12.008 |pmid=25525884 |issn=0092-8674|doi-access=free }}
* {{Cite journal |last1=Ghosh |first1=Eshan |last2=Nidhi |first2=Kumari |last3=Shukla |first3=Arun K. |date=2014 |title=SnapShot: GPCR-Ligand Interactions |journal=Cell |volume=159 |issue=7 |pages=1712–1712.e1 |doi=10.1016/j.cell.2014.12.008 |pmid=25525884 |issn=0092-8674|doi-access=free }}
* {{Cite journal |last=Reiter |first=Eric |last2=Ahn |first2=Seungkirl |last3=Shukla |first3=Arun K. |last4=Lefkowitz |first4=Robert J. |date=2012-01-11 |title=Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors |journal=Annual Review of Pharmacology and Toxicology |volume=52 |issue=1 |pages=179–197 |doi=10.1146/annurev.pharmtox.010909.105800 |issn=0362-1642 |pmc=3628752 |pmid=21942629}}
* {{Cite journal |last1=Reiter |first1=Eric |last2=Ahn |first2=Seungkirl |last3=Shukla |first3=Arun K. |last4=Lefkowitz |first4=Robert J. |date=2012-01-11 |title=Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors |journal=Annual Review of Pharmacology and Toxicology |volume=52 |issue=1 |pages=179–197 |doi=10.1146/annurev.pharmtox.010909.105800 |issn=0362-1642 |pmc=3628752 |pmid=21942629}}
* {{Cite journal |last=Lefkowitz |first=Robert J. |last2=Yates |first2=John R. |last3=Shenoy |first3=Sudha K. |last4=Chen |first4=Minyong |last5=Zhao |first5=Yang |last6=Shukla |first6=Arun K. |last7=McClatchy |first7=Daniel B. |last8=Xiao |first8=Kunhong |date=2007-07-17 |title=Functional specialization of β-arrestin interactions revealed by proteomic analysis |journal=Proceedings of the National Academy of Sciences |language=en |volume=104 |issue=29 |pages=12011–12016 |doi=10.1073/pnas.0704849104 |issn=1091-6490 |pmc=1913545 |pmid=17620599}}
* {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Yates |first2=John R. |last3=Shenoy |first3=Sudha K. |last4=Chen |first4=Minyong |last5=Zhao |first5=Yang |last6=Shukla |first6=Arun K. |last7=McClatchy |first7=Daniel B. |last8=Xiao |first8=Kunhong |date=2007-07-17 |title=Functional specialization of β-arrestin interactions revealed by proteomic analysis |journal=Proceedings of the National Academy of Sciences |language=en |volume=104 |issue=29 |pages=12011–12016 |doi=10.1073/pnas.0704849104 |issn=1091-6490 |pmc=1913545 |pmid=17620599 |bibcode=2007PNAS..10412011X |doi-access=free }}
* {{Cite journal |last=Lefkowitz |first=Robert J. |last2=Whalen |first2=Erin J. |last3=Muehlbauer |first3=Michael J. |last4=Chen |first4=J. Ruthie |last5=Lam |first5=Christopher M. |last6=DeWire |first6=Scott M. |last7=Violin |first7=Jonathan D. |last8=Kovacs |first8=Jeffrey J. |last9=Shukla |first9=Arun K. |date=2009-05-01 |title=β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice |journal=The Journal of Clinical Investigation |language=en |volume=119 |issue=5 |pages=1312–1321 |doi=10.1172/JCI36806 |issn=0021-9738 |pmc=2673863 |pmid=19349687}}
* {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Whalen |first2=Erin J. |last3=Muehlbauer |first3=Michael J. |last4=Chen |first4=J. Ruthie |last5=Lam |first5=Christopher M. |last6=DeWire |first6=Scott M. |last7=Violin |first7=Jonathan D. |last8=Kovacs |first8=Jeffrey J. |last9=Shukla |first9=Arun K. |date=2009-05-01 |title=β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice |journal=The Journal of Clinical Investigation |language=en |volume=119 |issue=5 |pages=1312–1321 |doi=10.1172/JCI36806 |issn=0021-9738 |pmc=2673863 |pmid=19349687}}
* {{Cite journal |last=Lefkowitz |first=Robert J. |last2=Gygi |first2=Steven P. |last3=Ma'ayan |first3=Avi |last4=Mizuno |first4=Kensaku |last5=Cheng |first5=Yishan |last6=Lin |first6=Yuan |last7=Zhao |first7=Shan |last8=Lachmann |first8=Alexander |last9=Hernandez |first9=Marylens |date=2010-08-24 |title=Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) |journal=Proceedings of the National Academy of Sciences |language=en |volume=107 |issue=34 |pages=15299–15304 |doi=10.1073/pnas.1008461107 |issn=1091-6490 |pmc=2930550 |pmid=20686112}}
* {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Gygi |first2=Steven P. |last3=Ma'ayan |first3=Avi |last4=Mizuno |first4=Kensaku |last5=Cheng |first5=Yishan |last6=Lin |first6=Yuan |last7=Zhao |first7=Shan |last8=Lachmann |first8=Alexander |last9=Hernandez |first9=Marylens |date=2010-08-24 |title=Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) |journal=Proceedings of the National Academy of Sciences |language=en |volume=107 |issue=34 |pages=15299–15304 |doi=10.1073/pnas.1008461107 |issn=1091-6490 |pmc=2930550 |pmid=20686112 |bibcode=2010PNAS..10715299X |doi-access=free }}


== See also ==
== See also ==
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== External links ==
== External links ==
* {{Cite web |url=https://www.youtube.com/watch?v=2tJIEBO25AQ |title=Prof. Arun K Shukla @Department of Biological Sciences and Bioengineering |last=IIT KANPUR |date=16 August 2017 |access-date=2018-12-30}}
* {{Cite web |url=https://www.youtube.com/watch?v=2tJIEBO25AQ |title=Prof. Arun K Shukla @Department of Biological Sciences and Bioengineering |last=IIT KANPUR |website=[[YouTube]] |date=16 August 2017 |access-date=2018-12-30}}


{{N-BIOS Laureates 2010–2019}}
{{N-BIOS Laureates 2010–2019}}
{{SSBPST recipients in Biological Science}}
{{authority control}}
{{authority control}}


{{DEFAULTSORT:Shukla, Arun Kumar}}
{{DEFAULTSORT:Shukla, Arun Kumar}}
[[Category:Indian scientific authors]]
[[Category:Year of birth missing (living people)]]
[[Category:Year of birth missing (living people)]]
[[Category:N-BIOS Prize recipients]]
[[Category:N-BIOS Prize recipients]]
[[Category:People from Kanpur]]
[[Category:People from Kanpur]]
[[Category:Jawaharlal Nehru University alumni]]
[[Category:Jawaharlal Nehru University alumni]]
[[Category:Max Planck Institutes]]
[[Category:Max Planck Society alumni]]
[[Category:Duke University alumni]]
[[Category:Duke University alumni]]
[[Category:Duke University School of Medicine faculty]]
[[Category:Duke University School of Medicine faculty]]
[[Category:Stanford University alumni]]
[[Category:Stanford University alumni]]
[[Category:Indian Institute of Technology Kanpur faculty]]
[[Category:Academic staff of IIT Kanpur]]
[[Category:Indian biologists]]
[[Category:Indian biologists]]
[[Category:Indian academics]]
[[Category:Living people]]
[[Category:Living people]]

Latest revision as of 07:11, 29 January 2026


Arun Kumar Shukla
Born
Kushinagar, Uttar Pradesh, India
Alma mater
Known forStudies on G protein-coupled receptor
Awards
Scientific career
Fields
Institutions
Doctoral advisor

Arun Kumar Shukla is an Indian structural biologist and the Joy-Gill Chair professor at the department of biological sciences and bioengineering at the Indian Institute of Technology, Kanpur.[1] Known for his studies on G protein-coupled receptor, Shukla is a Wellcome Trust-DBT Intermediate Fellow and a recipient of the SwarnaJayanti Fellowship of the Department of Science and Technology.[2] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017/18. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science.[3] He was awarded the Infosys Prize 2023 in Life Sciences his outstanding contributions to the biology of G-protein coupled receptors (GPCRs).

Biography[edit | edit source]

IIT Kanpur

Dr. Arun Kumar Shukla was born on 1 November 1981[4] in Kushinagar in the Indian state of Uttar Pradesh,[5] earned his master's degree in biotechnology from Jawaharlal Nehru University after which he did his doctoral studies under the guidance of Hartmut Michel (Nobel Laureate, 1988) of Max Planck Institute of Biophysics.[1] His post-doctoral work was with Robert J. Lefkowitz (Nobel Laureate, 2012) of Duke University and Brian Kobilka (Nobel Laureate, 2012) of Stanford University and he started his career at Duke University as an assistant professor at their department of medicine. Returning to India, he joined the Indian Institute of Technology, Kanpur (IITK) at the Department of Biological Sciences and Bioengineering (BSBE)[6] where he holds the position of a professor[7] and heads the Laboratory of GPCR Biology.[8]

Shukla is known to have carried out extensive research on G protein-coupled receptor and his research is reported to have led to easier regulation of these receptors for better drug efficacy.[9] He led a team of IITK scientists who developed nanomachines which could be designed to selectively target signalling events inside living cells.[10] The technique developed by them is in use with several drugs that are available in the market such as Telmisartan, Olmesartan, Fexofenadine, Propranolol, and Metoprolol.[5] He has published a number of articles and has contributed chapters to books published by others;[11][note 1] Google Scholar, an online repository of scientific articles has listed 75 of them.[12]

Awards and honours[edit | edit source]

Shukla received the Infosys Prize 2023 in Life Sciences, he was selected for this prestigious award by an eminent jury chaired by MIT Professor, Mriganka Sur. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science.[3] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.[13] He has also received the B. M. Birla Science Prize (2017),[14] NASI-Young Scientist Platinum Jubilee Award of the National Academy of Sciences, India (2016),[15] CDRI Award (2018),[16] Shakuntala Amir Chand Prize of the Indian Council for Medical Research (2018)[17][18] and the EMBO Young Investigator Award (2017).[19] He was elected as a fellow of the Indian National Science Academy in 2022.[20] In 2022 and 2024, Shukla was a laureate of the Asian Scientist 100 by the Asian Scientist.

Selected bibliography[edit | edit source]

See also[edit | edit source]

Notes[edit | edit source]

  1. ↑ Please see Selected bibliography section

References[edit | edit source]

  1. ↑ 1.0 1.1 "Arun K. Shukla IITK". www.iitk.ac.in. 30 December 2018. Retrieved 30 December 2018.
  2. ↑ "List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18" (PDF). Department of Science and Technology. 30 December 2018. Retrieved 30 December 2018.
  3. ↑ 3.0 3.1 "Shanti Swarup Bhatnagar Prize (SSB) for Science and Technology 2021" (PDF). sbprize.gov.in. Council of Scientific and Industrial Research. Retrieved 26 September 2021.
  4. ↑ "Arun Kumar Shukla Biography". Online Hindi world. 27 November 2021.
  5. ↑ 5.0 5.1 "Better pill". www.telegraphindia.com. 30 December 2018. Retrieved 30 December 2018.
  6. ↑ "BSBE People". www.iitk.ac.in. 30 December 2018. Retrieved 30 December 2018.
  7. ↑ "Arun Shukla on Samviti". samviti.com. 30 December 2018. Retrieved 30 December 2018.
  8. ↑ "Principal Investigator - Laboratory of GPCR Biology". sites.google.com. 30 December 2018. Retrieved 30 December 2018.
  9. ↑ Prasad, R. (1 January 2017). "Drug discovery for GPCR signalling made easy by IIT Kanpur". The Hindu. Retrieved 30 December 2018.
  10. ↑ Jayan, T. V. (8 January 2018). "IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells". @businessline. Retrieved 30 December 2018.
  11. ↑ "Research Publications - Laboratory of GPCR Biology". sites.google.com. 31 December 2018. Retrieved 31 December 2018.
  12. ↑ "Arun K. Shukla - Google Scholar Citations". scholar.google.co.in. 31 December 2018. Retrieved 31 December 2018.
  13. ↑ "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Archived from the original (PDF) on 4 March 2018. Retrieved 20 November 2017.
  14. ↑ "BM Birla Science Prize presented". www.thehansindia.com. 31 December 2018. Retrieved 31 December 2018.
  15. ↑ "The National Academy of Sciences, India - Activities". www.nasi.org.in. 31 December 2018. Archived from the original on 9 January 2019. Retrieved 31 December 2018.
  16. ↑ "List of previous CDRI Awardees" (PDF). Central Drug Research Institute. 31 December 2018. Archived from the original (PDF) on 31 December 2018. Retrieved 31 December 2018.
  17. ↑ "Awards - Indian Council of Medical Research". ICMR. 31 December 2018. Archived from the original on 31 December 2018. Retrieved 31 December 2018.
  18. ↑ Vishwas (31 December 2018). "News Archive". www.iitk.ac.in. Retrieved 31 December 2018.
  19. ↑ "IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator". Pinterest. 30 December 2018. Retrieved 30 December 2018.
  20. ↑ "INSA :: Indian Fellows Elected". www.insaindia.res.in. Retrieved 22 October 2022.

Further reading[edit | edit source]

External links[edit | edit source]

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