Epidemics

Local

First plague pandemic (541–767)
Plague of Justinian (541–542)
Roman Plague (590)
Plague of Sheroe (627–628)
Plague of Amwas (638–639)
Plague of 664 (664–689)
Japanese smallpox (735–737)
Black Death (1346–1353)
Sweating sickness (1485–1551)

16th century	Influenza pandemic (1510) Mexican smallpox (1520) Influenza pandemic (1557–1559) London plague (1563–1564) Maltese plague (1592–1593) London plague (1592–1593) Atlantic plague (1596–1602)

17th century	Maltese plague (1623) Italian plague (1629–1631) Massachusetts smallpox (1633) Great Plague in late Ming Dynasty (1633–1644) Great Plague of Seville (1647–1652) Maltese plague (1655) Naples Plague (1656) Great Plague of London (1665–1666) Maltese plague (1675–1676) Great Plague of Vienna (1679)

18th century	Great Northern War plague (1710–1712) Great Plague of Marseille (1720–1722) Great Plague of 1738 (1738) Russian plague (1770–1772) Persian Plague (1772) North American smallpox (1780–1782) Philadelphia yellow fever (1793–1798)

19th century	Ottoman plague (1812–1819) Maltese plague (1813–1814) Caragea's plague (1813) Groningen epidemic (1829) Great Plains smallpox (1837–1838) Typhus (1847–1848) Copenhagen cholera (1853) Stockholm cholera (1853) Broad Street cholera (1854) Guam smallpox (1856) Pacific Northwest smallpox (1862–1863) Barcelona yellow fever (1870) Buenos Aires yellow fever (1871)

20th century	San Francisco plague (1900–1904) Manchurian plague (1910–1911) LA pneumonic plague (1924) Croydon typhoid (1937) NYC smallpox (1947) Yugoslav smallpox (1972) London flu (1972–1973) Indian smallpox (1974) Surat plague (1994) Malaysian Nipah virus (1998–1999)

21st century

Second plague pandemic (1348–19th century)
Influenza pandemic (1510)
Influenza pandemic (1557–1559)
First cholera pandemic (1816–1826)
Second cholera pandemic (1829–1851)
Third cholera pandemic (1852–1860)
Third plague pandemic (1855–1960)
Fourth cholera pandemic (1863–1879)
Fifth cholera pandemic (1881–1896)
Russian flu (1889–1890)
Sixth cholera pandemic (1899–1923)
Spanish flu (1918–1920)
Asian flu (1957–1958)
Seventh cholera pandemic (1961–1975)
Hong Kong flu (1968–1970)
Russian flu pandemic (1977–1979)
HIV/AIDS (1981–present)
Swine flu (2009–2010)
COVID-19 (2019–present)

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