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{{Short description|Indian molecular biologist}} | |||
{{Use dmy dates|date=May 2018}} | {{Use dmy dates|date=May 2018}} | ||
{{Use Indian English|date=May 2018}} | {{Use Indian English|date=May 2018}} | ||
{{Infobox person | {{Infobox person | ||
| name | | name = Sandip Kumar Basu | ||
| image | | image = | ||
| imagesize | | imagesize = | ||
| caption | | caption = | ||
| birth_date | | birth_date = {{Birth year and age|1944}} | ||
| birth_place | | birth_place = [[Kolkata]], [[West Bengal]], India | ||
| death_date | | death_date = | ||
| death_place | | death_place = | ||
| restingplace | | restingplace = | ||
| restingplacecoordinates = | | restingplacecoordinates = | ||
| othername | | othername = | ||
| occupation | | occupation = | ||
| yearsactive | | yearsactive = since 1975 | ||
| known for | | known for = | ||
| spouse | | spouse = | ||
| domesticpartner | | domesticpartner = | ||
| children | | children = | ||
| parents | | parents = | ||
| website | | website = | ||
| awards | | awards = [[Padma Shri]]<br>[[Ranbaxy]] Medical Sciences Award<br>[[FICCI]] Life Sciences Award<br>Bhasin Foundation Biotechnology Award<br>[[Indian Council of Medical Research|ICMR]] B. R. Ambedkar Award<br>ISCA R. K. Dutt Memorial Award<br>Goyal Prize | ||
}} | }} | ||
'''Sandip Kumar Basu''' (born 1944) is an Indian molecular biologist and the holder of the J. C. Bose Chair of the [[National Academy of Sciences, India]], who is credited with innovations in the treatment protocols of [[leishmaniasis]], [[tuberculosis]], viral infections, multidrug resistant cancer and [[arterosclerosis]].<ref name="INSA">{{cite web | url=http://insaindia.org.in/detail.php?id=N94-1140 | title=INSA | publisher=INSA | date=2014 | access-date=5 January 2015}}</ref> He was honored by the [[Government of India]], in 2001, with the fourth highest [[Indian honours system|Indian civilian award]] of [[Padma Shri]].<ref name="Padma Awards">{{cite web | url=http://mha.nic.in/sites/upload_files/mha/files/LST-PDAWD-2013.pdf | title=Padma Awards | publisher=Padma Awards | date=2014 | access-date=11 November 2014}}</ref> | '''Sandip Kumar Basu''' (born 1944) is an Indian molecular biologist and the holder of the J. C. Bose Chair of the [[National Academy of Sciences, India]], who is credited with innovations in the treatment protocols of [[leishmaniasis]], [[tuberculosis]], viral infections, multidrug resistant cancer and [[arterosclerosis]].<ref name="INSA">{{cite web | url=http://insaindia.org.in/detail.php?id=N94-1140 | archive-url=https://web.archive.org/web/20160812222652/http://insaindia.org.in/detail.php?id=N94-1140 | url-status=usurped | archive-date=12 August 2016 | title=INSA | publisher=INSA | date=2014 | access-date=5 January 2015}}</ref> He was honored by the [[Government of India]], in 2001, with the fourth highest [[Indian honours system|Indian civilian award]] of [[Padma Shri]].<ref name="Padma Awards">{{cite web | url=http://mha.nic.in/sites/upload_files/mha/files/LST-PDAWD-2013.pdf | title=Padma Awards | publisher=Padma Awards | date=2014 | access-date=11 November 2014 | archive-date=15 October 2015 | archive-url=https://web.archive.org/web/20151015193758/http://mha.nic.in/sites/upload_files/mha/files/LST-PDAWD-2013.pdf | url-status=dead }}</ref> | ||
==Biography== | ==Biography== | ||
Sandip Kumar Basu was born in Kolkata in the Indian state of West Bengal.<ref name="INSA" /> He graduated in 1962 from the [[Presidency College, Calcutta]] and secured his master's degree in 1964 from the [[Rajabazar Science College|University College of Science]]. His doctoral research was at the [[Calcutta University]] which he successfully completed in 1968 on the topic, ''regulation of microbial metabolism'' and moved to USA for post doctoral research at [[Keck School of Medicine of USC]], Los Angeles, [[University of California, Irvine School of Medicine]], [[Public Health Research Institute]], New York and [[Michael Reese Hospital]], Chicago.<ref name="INSA" /> In 1975, he started his professional career by joining the [[University of Texas Southwestern Medical School]] as a faculty member and stayed there till 1983 when he returned to India to join the [[Indian Institute of Chemical Biology]], Kolkata. His next move was as the director of the [[Institute of Microbial Technology]], Chandigarh in 1986.<ref name="INSA" /> He became the director of the [[National Institute of Immunology, India|National Institute of Immunology]], New Delhi in 1991, a post he held till 2005 when he became the Professor of Eminence of the institute and continued there till 2010. He is the [[J. C. Bose]] Chair Professor of the [[National Academy of Sciences, India]], placed at the [[National Institute of Science Communication and Information Resources]] of the [[Council of Scientific and Industrial Research]].<ref name="INSA" /> | Sandip Kumar Basu was born in [[Kolkata]] in the Indian state of [[West Bengal]].<ref name="INSA" /> He graduated in 1962 from the [[Presidency College, Calcutta]] and secured his master's degree in 1964 from the [[Rajabazar Science College|University College of Science]]. His doctoral research was at the [[Calcutta University]] which he successfully completed in 1968 on the topic, ''regulation of [[Microorganism|microbial]] [[metabolism]]'' and moved to USA for post doctoral research at [[Keck School of Medicine of USC]], Los Angeles, [[University of California, Irvine School of Medicine]], [[Public Health Research Institute]], New York and [[Michael Reese Hospital]], Chicago.<ref name="INSA" /> In 1975, he started his professional career by joining the [[University of Texas Southwestern Medical School]] as a faculty member and stayed there till 1983 when he returned to India to join the [[Indian Institute of Chemical Biology]], Kolkata. His next move was as the director of the [[Institute of Microbial Technology]], Chandigarh in 1986.<ref name="INSA" /> He became the director of the [[National Institute of Immunology, India|National Institute of Immunology]], New Delhi in 1991, a post he held till 2005 when he became the Professor of Eminence of the institute and continued there till 2010. He is the [[J. C. Bose]] Chair Professor of the [[National Academy of Sciences, India]], placed at the [[National Institute of Science Communication and Information Resources]] of the [[Council of Scientific and Industrial Research]].<ref name="INSA" /> | ||
Basu has been involved with research on the receptor based intracellular delivery of drugs.<ref name="ResearchGate">{{cite web | url=https://www.researchgate.net/profile/Sandip_Basu5 | title=ResearchGate | date=2014 | access-date=5 January 2015}}</ref><ref name="NISCAIR">{{cite web | url=http://nopr.niscair.res.in/handle/123456789/39/items-by-author?author=Basu%2C+Sandip+Kumar | title=NISCAIR | publisher=NISCAIR | date=2014 | access-date=5 January 2015}}</ref><ref name="Microsoft Academic Search">{{cite web | url=http://libra.msra.cn/PublicationList?srcType=4&desType=2&srcID=7767&desID=52290139 | title=Microsoft Academic Search | publisher=Microsoft Academic Search | date=2014 | access-date=5 January 2015}}</ref><ref name="PubFacts">{{cite web | url=http://www.pubfacts.com/author/Sandip+Kumar+Basu | title=PubFacts | publisher=PubFacts | date=2014 | access-date=5 January 2015}}</ref> He is known to have introduced a new approach of ''scavenger receptor-mediated targeting of therapeutic agents'' which has been demonstrated to be more effective than conventional [[chemotherapy]], in the treatment of [[leishmaniasis]], [[tuberculosis]], viral infections, and multidrug resistant cancer.<ref name="INSA" /> His research has led to the discovery of new drug targets and also demonstrated the therapeutic effect of immunomodulator muramyl dipeptide on [[salmonella]] by diverting the route the pathogens follow so as to survive within the [[macrophages]].<ref name="INSA" /> He is credited with the establishment of the pathway of [[low density lipoprotein]] receptors.<ref name="The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages">{{cite journal | title=The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages |author1=Michael S Brown |author2=Sandip K Basu |author3=JR Falck |author4=YK Ho |author5=Joseph L Goldstein | journal=Journal of Supramolecular Structure | year=1980 | volume=13 | issue=1 | pages=67–81 | doi=10.1002/jss.400130107|pmid = 6255257}}</ref><ref>{{Cite journal |doi = 10.1073/pnas.76.1.333|pmid = 218198|pmc = 382933|title = Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition|journal = Proceedings of the National Academy of Sciences|volume = 76|issue = 1|pages = 333–337|year = 1979|last1 = Goldstein|first1 = J. L.|last2 = Ho|first2 = Y. K.|last3 = Basu|first3 = S. K.|last4 = Brown|first4 = M. S.|bibcode = 1979PNAS...76..333G}}</ref> It is reported that Basu's work assisted [[Michael Stuart Brown]] and [[Joseph L. Goldstein]], 1985 [[Nobel Prize]] winners and his co-authors, in their research and in the development of [[statins]], the cholesterol lowering drug.<ref name="INSA" /><ref name="Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans">{{cite journal | title=Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans |author1=Goldstein JL |author2=Basu SK |author3=Brunschede GY |author4=Brown MS | journal=Cell |date=January 1976 | volume=7 | issue=1 | pages=85–95 | pmid=181140 | doi=10.1016/0092-8674(76)90258-0 |s2cid=23110979 }}</ref><ref name="Google Scholar">{{cite web | url=https://scholar.google.com/citations?user=XATuveIAAAAJ&hl=en | title=Google Scholar | publisher=Google Scholar | date=2014 | access-date=5 January 2015}}</ref> | Basu has been involved with research on the receptor based [[Drug delivery|intracellular delivery of drugs]].<ref name="ResearchGate">{{cite web | url=https://www.researchgate.net/profile/Sandip_Basu5 | title=ResearchGate | date=2014 | access-date=5 January 2015}}</ref><ref name="NISCAIR">{{cite web | url=http://nopr.niscair.res.in/handle/123456789/39/items-by-author?author=Basu%2C+Sandip+Kumar | title=NISCAIR | publisher=NISCAIR | date=2014 | access-date=5 January 2015}}</ref><ref name="Microsoft Academic Search">{{cite web | url=http://libra.msra.cn/PublicationList?srcType=4&desType=2&srcID=7767&desID=52290139 | title=Microsoft Academic Search | publisher=Microsoft Academic Search | date=2014 | access-date=5 January 2015}}</ref><ref name="PubFacts">{{cite web | url=http://www.pubfacts.com/author/Sandip+Kumar+Basu | title=PubFacts | publisher=PubFacts | date=2014 | access-date=5 January 2015}}</ref> He is known to have introduced a new approach of ''[[Scavenger receptor (immunology)|scavenger receptor]]-mediated targeting of therapeutic agents'' which has been demonstrated to be more effective than conventional [[chemotherapy]], in the treatment of [[leishmaniasis]], [[tuberculosis]], viral infections, and multidrug resistant cancer.<ref name="INSA" /> His research has led to the discovery of new drug targets and also demonstrated the therapeutic effect of immunomodulator muramyl dipeptide on [[salmonella]] by diverting the route the pathogens follow so as to survive within the [[macrophages]].<ref name="INSA" /> He is credited with the establishment of the pathway of [[low density lipoprotein]] receptors.<ref name="The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages">{{cite journal | title=The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages |author1=Michael S Brown |author2=Sandip K Basu |author3=JR Falck |author4=YK Ho |author5=Joseph L Goldstein | journal=Journal of Supramolecular Structure | year=1980 | volume=13 | issue=1 | pages=67–81 | doi=10.1002/jss.400130107|pmid = 6255257}}</ref><ref>{{Cite journal |doi = 10.1073/pnas.76.1.333|pmid = 218198|pmc = 382933|title = Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition|journal = Proceedings of the National Academy of Sciences|volume = 76|issue = 1|pages = 333–337|year = 1979|last1 = Goldstein|first1 = J. L.|last2 = Ho|first2 = Y. K.|last3 = Basu|first3 = S. K.|last4 = Brown|first4 = M. S.|bibcode = 1979PNAS...76..333G|doi-access = free}}</ref> It is reported that Basu's work assisted [[Michael Stuart Brown]] and [[Joseph L. Goldstein]], 1985 [[Nobel Prize]] winners and his co-authors, in their research and in the development of [[statins]], the cholesterol lowering drug.<ref name="INSA" /><ref name="Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans">{{cite journal | title=Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans |author1=Goldstein JL |author2=Basu SK |author3=Brunschede GY |author4=Brown MS | journal=Cell |date=January 1976 | volume=7 | issue=1 | pages=85–95 | pmid=181140 | doi=10.1016/0092-8674(76)90258-0 |s2cid=23110979 }}</ref><ref name="Google Scholar">{{cite web | url=https://scholar.google.com/citations?user=XATuveIAAAAJ&hl=en | title=Google Scholar | publisher=Google Scholar | date=2014 | access-date=5 January 2015}}</ref> | ||
Basu is also credited with administrative achievements such as the establishment of a permanent campus at the [[Institute of Microbial Technology]], Chandigarh.<ref name="INSA" /> A former member of the Scientific Advisory Committee to the [[Government of India]], he has served as the council member of [[Indian National Science Academy]], the [[Indian Academy of Sciences]] and [[National Academy of Sciences, India]] and has also been the general secretary and vice president of NASI.<ref name="INSA" /> | Basu is also credited with administrative achievements such as the establishment of a permanent campus at the [[Institute of Microbial Technology]], Chandigarh.<ref name="INSA" /> A former member of the Scientific Advisory Committee to the [[Government of India]], he has served as the council member of [[Indian National Science Academy]], the [[Indian Academy of Sciences]] and [[National Academy of Sciences, India]] and has also been the general secretary and vice president of NASI.<ref name="INSA" /> | ||
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* {{cite journal | title=The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages |author1=Michael S Brown |author2=Sandip K Basu |author3=JR Falck |author4=YK Ho |author5=Joseph L Goldstein | journal=Journal of Supramolecular Structure | year=1980 | volume=13 | issue=1 | pages=67–81 | doi=10.1002/jss.400130107|pmid = 6255257}} | * {{cite journal | title=The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages |author1=Michael S Brown |author2=Sandip K Basu |author3=JR Falck |author4=YK Ho |author5=Joseph L Goldstein | journal=Journal of Supramolecular Structure | year=1980 | volume=13 | issue=1 | pages=67–81 | doi=10.1002/jss.400130107|pmid = 6255257}} | ||
{{Padma Shri Award Recipients in Science & Engineering}} | {{2000s Padma Shri Award Recipients in Science & Engineering}} | ||
{{authority control}} | {{authority control}} | ||
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[[Category:Living people]] | [[Category:Living people]] | ||
[[Category:Indian molecular biologists]] | [[Category:Indian molecular biologists]] | ||
[[Category:Fellows of | [[Category:Fellows of the National Academy of Sciences, India]] | ||
[[Category:Fellows of the Indian Academy of Sciences]] | [[Category:Fellows of the Indian Academy of Sciences]] | ||
[[Category:Fellows of the Indian National Science Academy]] | [[Category:Fellows of the Indian National Science Academy]] | ||
[[Category:20th-century Indian biologists]] | [[Category:20th-century Indian biologists]] | ||
Latest revision as of 04:46, 25 September 2025
Sandip Kumar Basu | |
|---|---|
| Born | 1944 (age 81–82) Kolkata, West Bengal, India |
| Years active | since 1975 |
| Awards | Padma Shri Ranbaxy Medical Sciences Award FICCI Life Sciences Award Bhasin Foundation Biotechnology Award ICMR B. R. Ambedkar Award ISCA R. K. Dutt Memorial Award Goyal Prize |
Sandip Kumar Basu (born 1944) is an Indian molecular biologist and the holder of the J. C. Bose Chair of the National Academy of Sciences, India, who is credited with innovations in the treatment protocols of leishmaniasis, tuberculosis, viral infections, multidrug resistant cancer and arterosclerosis.[1] He was honored by the Government of India, in 2001, with the fourth highest Indian civilian award of Padma Shri.[2]
Biography[edit | edit source]
Sandip Kumar Basu was born in Kolkata in the Indian state of West Bengal.[1] He graduated in 1962 from the Presidency College, Calcutta and secured his master's degree in 1964 from the University College of Science. His doctoral research was at the Calcutta University which he successfully completed in 1968 on the topic, regulation of microbial metabolism and moved to USA for post doctoral research at Keck School of Medicine of USC, Los Angeles, University of California, Irvine School of Medicine, Public Health Research Institute, New York and Michael Reese Hospital, Chicago.[1] In 1975, he started his professional career by joining the University of Texas Southwestern Medical School as a faculty member and stayed there till 1983 when he returned to India to join the Indian Institute of Chemical Biology, Kolkata. His next move was as the director of the Institute of Microbial Technology, Chandigarh in 1986.[1] He became the director of the National Institute of Immunology, New Delhi in 1991, a post he held till 2005 when he became the Professor of Eminence of the institute and continued there till 2010. He is the J. C. Bose Chair Professor of the National Academy of Sciences, India, placed at the National Institute of Science Communication and Information Resources of the Council of Scientific and Industrial Research.[1]
Basu has been involved with research on the receptor based intracellular delivery of drugs.[3][4][5][6] He is known to have introduced a new approach of scavenger receptor-mediated targeting of therapeutic agents which has been demonstrated to be more effective than conventional chemotherapy, in the treatment of leishmaniasis, tuberculosis, viral infections, and multidrug resistant cancer.[1] His research has led to the discovery of new drug targets and also demonstrated the therapeutic effect of immunomodulator muramyl dipeptide on salmonella by diverting the route the pathogens follow so as to survive within the macrophages.[1] He is credited with the establishment of the pathway of low density lipoprotein receptors.[7][8] It is reported that Basu's work assisted Michael Stuart Brown and Joseph L. Goldstein, 1985 Nobel Prize winners and his co-authors, in their research and in the development of statins, the cholesterol lowering drug.[1][9][10]
Basu is also credited with administrative achievements such as the establishment of a permanent campus at the Institute of Microbial Technology, Chandigarh.[1] A former member of the Scientific Advisory Committee to the Government of India, he has served as the council member of Indian National Science Academy, the Indian Academy of Sciences and National Academy of Sciences, India and has also been the general secretary and vice president of NASI.[1]
Awards and honors[edit | edit source]
Sandip Kumar Basu is an elected Fellow of the Indian National Science Academy, the Indian Academy of Sciences (FASc),[11] The World Academy of Sciences (FTWAS),[12] and the National Academy of Sciences, India (FNASc).[13] He delivered the Professor MRN Prasad Memorial Award Lecture in 1995, the Dr. Yellapragada SubbaRow Memorial Award Lecture in 2002 and the B. K. Bachhawat Award Lecture in 2006.[1] He received the Ranbaxy Medical Sciences Award in 1995 followed by FICCI Life Sciences Award in 1996 and Bhasin Foundation Biotechnology Award, the next year. The year 1999 brought him two awards, the B. R. Ambedkar Award of the Indian Council of Medical Research and the R. K. Dutt Memorial Award of the International Science Congress Associations.[1] A recipient of the Goyal Prize in 2003, Basu was awarded the civilian honour of Padma Shri by the Government of India in 2001.
See also[edit | edit source]
References[edit | edit source]
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 "INSA". INSA. 2014. Archived from the original on 12 August 2016. Retrieved 5 January 2015.
- ↑ "Padma Awards" (PDF). Padma Awards. 2014. Archived from the original (PDF) on 15 October 2015. Retrieved 11 November 2014.
- ↑ "ResearchGate". 2014. Retrieved 5 January 2015.
- ↑ "NISCAIR". NISCAIR. 2014. Retrieved 5 January 2015.
- ↑ "Microsoft Academic Search". Microsoft Academic Search. 2014. Retrieved 5 January 2015.
- ↑ "PubFacts". PubFacts. 2014. Retrieved 5 January 2015.
- ↑ Michael S Brown; Sandip K Basu; JR Falck; YK Ho; Joseph L Goldstein (1980). "The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages". Journal of Supramolecular Structure. 13 (1): 67–81. doi:10.1002/jss.400130107. PMID 6255257.
- ↑ Goldstein, J. L.; Ho, Y. K.; Basu, S. K.; Brown, M. S. (1979). "Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition". Proceedings of the National Academy of Sciences. 76 (1): 333–337. Bibcode:1979PNAS...76..333G. doi:10.1073/pnas.76.1.333. PMC 382933. PMID 218198.
- ↑ Goldstein JL; Basu SK; Brunschede GY; Brown MS (January 1976). "Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans". Cell. 7 (1): 85–95. doi:10.1016/0092-8674(76)90258-0. PMID 181140. S2CID 23110979.
- ↑ "Google Scholar". Google Scholar. 2014. Retrieved 5 January 2015.
- ↑ "IAS". IAS. 2014. Retrieved 5 January 2015.
- ↑ "TWAS". TWAS. 2014. Retrieved 5 January 2015.
- ↑ "NII". NII. 2014. Retrieved 5 January 2015.
External links[edit | edit source]
- Goldstein JL; Basu SK; Brunschede GY; Brown MS (January 1976). "Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans". Cell. 7 (1): 85–95. doi:10.1016/0092-8674(76)90258-0. PMID 181140. S2CID 23110979.
- Michael S Brown; Sandip K Basu; JR Falck; YK Ho; Joseph L Goldstein (1980). "The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages". Journal of Supramolecular Structure. 13 (1): 67–81. doi:10.1002/jss.400130107. PMID 6255257.
Template:2000s Padma Shri Award Recipients in Science & Engineering