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{{Infobox scientist | {{Infobox scientist | ||
| name = Dr.Guru Prakash Dutta | | name = Dr. Guru Prakash Dutta | ||
| image = | | image = | ||
| alt = | | alt = | ||
| caption = | | caption = | ||
| birth_date = {{birth date | | birth_date = {{birth date|df=yes|1933|11|19}} | ||
| birth_place = India | | birth_place = India | ||
| death_date = 25 | | death_date = {{Death date and age|2021|4|25|1933|11|19|df=y}} | ||
| death_place = | | death_place = | ||
| residence = | | residence = | ||
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| awards = 1976 [[Shanti Swarup Bhatnagar Prize]] | | awards = 1976 [[Shanti Swarup Bhatnagar Prize]] | ||
}} | }} | ||
'''Guru Prakash Dutta''' (1933- 2021) was an Indian cell biologist and [[immunologist]], known for his contributions to the subjects of Experimental [[protozoology]] and [[Immunology]].<ref name="Brief Profile of the Awardee">{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=449 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=19 September 2016}}</ref> His researches are reported to have assisted in the development of a number of [[anti-malarial]] drugs.<ref name="Indian Fellow - G. P. Dutta">{{cite web | url=http://insaindia.res.in/detail.php?id=N84-0230 | title=Indian Fellow - G. P. Dutta | publisher=Indian National Science Academy | date=2016 | access-date=21 September 2016}}</ref> He | '''Guru Prakash Dutta''' (19 November 1933 - 25 April 2021) was an Indian cell biologist and [[immunologist]], known for his contributions to the subjects of Experimental [[protozoology]] and [[Immunology]].<ref>{{cite web |title=Obituary |url=https://link.springer.com/article/10.1007/s12639-021-01406-w |publisher=Springer Link |access-date=12 August 2021}}</ref><ref name="Brief Profile of the Awardee">{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=449 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=19 September 2016}}</ref> His researches are reported to have assisted in the development of a number of [[anti-malarial]] drugs.<ref name="Indian Fellow - G. P. Dutta">{{cite web | url=http://insaindia.res.in/detail.php?id=N84-0230 | title=Indian Fellow - G. P. Dutta | publisher=Indian National Science Academy | date=2016 | access-date=21 September 2016}}</ref> He was an elected fellow of the [[Indian National Science Academy]], [[National Academy of Sciences, India]] and Indian Society of Parasitology. The [[Council of Scientific and Industrial Research]], the apex agency of the Government of India for scientific research, awarded him the [[Shanti Swarup Bhatnagar Prize for Science and Technology]], one of the highest Indian science awards, in 1976, for his contributions to biological sciences.<ref name="View Bhatnagar Awardees">{{cite web | url=http://ssbprize.gov.in/Content/AwardeeList.aspx | title=View Bhatnagar Awardees | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=19 September 2016}}</ref> | ||
== Biography == | == Biography == | ||
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Dutta, whose researches on experimental [[protozoology]] assisted in a wider understanding of [[protozoa]] and its functional [[Morphology (biology)|morphology]], is known to have developed new techniques for the culture of those unicellular [[eukaryotic]] organisms and studied their metabolic and growth responses to ''physico-chemical'' factors, with special emphasis on [[Entamoeba histolytica]], an [[Anaerobic organism|anaerobic]] parasite which causes [[amoebiasis]].<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=19 September 2016 | pages=36 | archive-url=https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf | archive-date=4 March 2016 | url-status=dead }}</ref> His work on the antimalarial drugs helped in the development of several fast-acting drugs and ''alpha/beta'' [[arteether]], ''alpha'' and ''beta'' [[arteether]], ''alpha'' and ''beta'' artelinate, [[dihydroartemisinin]], [[pyronaridine]], bulaquine and Tefenoquine are some of drugs developed with the assistance of his researches.<ref name="Indian Fellow - G. P. Dutta" />{{Refn|group=note|It is reported that 30 patents have been granted for drugs based on Dutta's researches.<ref name="Indian Fellow - G. P. Dutta" />}} | Dutta, whose researches on experimental [[protozoology]] assisted in a wider understanding of [[protozoa]] and its functional [[Morphology (biology)|morphology]], is known to have developed new techniques for the culture of those unicellular [[eukaryotic]] organisms and studied their metabolic and growth responses to ''physico-chemical'' factors, with special emphasis on [[Entamoeba histolytica]], an [[Anaerobic organism|anaerobic]] parasite which causes [[amoebiasis]].<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=19 September 2016 | pages=36 | archive-url=https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf | archive-date=4 March 2016 | url-status=dead }}</ref> His work on the antimalarial drugs helped in the development of several fast-acting drugs and ''alpha/beta'' [[arteether]], ''alpha'' and ''beta'' [[arteether]], ''alpha'' and ''beta'' artelinate, [[dihydroartemisinin]], [[pyronaridine]], bulaquine and Tefenoquine are some of drugs developed with the assistance of his researches.<ref name="Indian Fellow - G. P. Dutta" />{{Refn|group=note|It is reported that 30 patents have been granted for drugs based on Dutta's researches.<ref name="Indian Fellow - G. P. Dutta" />}} | ||
Dutta's researches have been detailed in over 275 articles<ref name="Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin">{{cite journal | title=Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin |author1=R. A. Vishwakarma |author2=R. Mehrotra |author3=R. Tripathi |author4=G. P. Dutta | journal=J. Nat. Prod. | year=1992 | volume=55 | issue=8 | pages=1142–1144 | doi=10.1021/np50086a018|pmid=1431937 }}</ref><ref name="Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo">{{cite journal | url=https://www.researchgate.net/publication/7018115 | title=Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo |author1=Renu Tripathi |author2=Charles W Jefford |author3=G P Dutta | journal=Parasitology | date=August 2006 | volume=133 | issue=1 | pages=1–9 | doi=10.1017/s0031182006009905| pmid=16764736 }}</ref> and two books, ''Antimalarial Drug Development and Prophylaxis against Malaria'' and ''Experimental and Clinical Studies on Amoebiasis''.<ref name="Experimental and Clinical Studies on Amoebiasis">{{cite book | title=Experimental and Clinical Studies on Amoebiasis | publisher=Tata-McGraw Hill | author=G. P. Dutta | year=1982 | pages=390 | isbn=978-0070963955}}</ref> The [[International Review of Cytology]] of [[Academic Press]] has published five | Dutta's researches have been detailed in over 275 articles<ref name="Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin">{{cite journal | title=Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin |author1=R. A. Vishwakarma |author2=R. Mehrotra |author3=R. Tripathi |author4=G. P. Dutta | journal=J. Nat. Prod. | year=1992 | volume=55 | issue=8 | pages=1142–1144 | doi=10.1021/np50086a018|pmid=1431937 }}</ref><ref name="Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo">{{cite journal | url=https://www.researchgate.net/publication/7018115 | title=Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo |author1=Renu Tripathi |author2=Charles W Jefford |author3=G P Dutta | journal=Parasitology | date=August 2006 | volume=133 | issue=1 | pages=1–9 | doi=10.1017/s0031182006009905| pmid=16764736 }}</ref> and two books, ''Antimalarial Drug Development and Prophylaxis against Malaria'' and ''Experimental and Clinical Studies on Amoebiasis''.<ref name="Experimental and Clinical Studies on Amoebiasis">{{cite book | title=Experimental and Clinical Studies on Amoebiasis | publisher=Tata-McGraw Hill | author=G. P. Dutta | year=1982 | pages=390 | isbn=978-0070963955}}</ref> The [[International Review of Cytology]] of [[Academic Press]] has published five reviews, three on [[Cytochemistry]] and ultrastructure of Protozoa and two on [[Amoebiasis]] and [[ResearchGate]], an online repository of scientific articles, has listed 130 of his papers.<ref name="G P Dutta on ResearchGate">{{cite web | url=https://www.researchgate.net/researcher/39654454_G_P_Dutta | title=G P Dutta on ResearchGate | work=Author search | date=2016 | access-date=21 September 2016}}</ref> He has been a collaborator for [[Walter Reed Army Institute of Research]] in two of their international programs on Malaria which ran between 1983 and 1994. He has also mentored 40 master's and doctoral scholars in their researches.<ref name="Indian Fellow - G. P. Dutta" /> | ||
Dutta received the degree of Doctor of Science from the [[Punjab University, Chandigarh, India|Punjab University]] in 1973 and the [[Council of Scientific and Industrial Research]] awarded him the [[Shanti Swarup Bhatnagar Prize]], one of the highest Indian science awards, for his contributions to biological sciences in 1976.<ref name="Brief Profile of the Awardee" /> The [[Indian National Science Academy]] elected him as their fellow in 1984 and the [[National Academy of Sciences, India]] followed INSA with their fellowship in 1991.<ref name="NASI fellows">{{cite web | url=http://www.nasi.org.in/fellows.asp?RsFilter=D | title=NASI fellows | publisher=National Academy of Sciences, India | date=2016 | access-date=22 September 2016}}</ref> He was also elected by the Indian Society for Parasitology as a fellow in 1993.<ref name="Fellows - ISP">{{cite web | url=http://www.parasitologyindia.org/fellows.htm | title=Fellows - ISP | publisher=Indian Society for Parasitology | date=2016 | access-date=21 September 2016 | archive-url=https://web.archive.org/web/20141213195132/http://www.parasitologyindia.org/fellows.htm | archive-date=13 December 2014 | url-status=dead | df=dmy-all }}</ref> | Dutta received the degree of Doctor of Science from the [[Punjab University, Chandigarh, India|Punjab University]] in 1973 and the [[Council of Scientific and Industrial Research]] awarded him the [[Shanti Swarup Bhatnagar Prize]], one of the highest Indian science awards, for his contributions to biological sciences in 1976.<ref name="Brief Profile of the Awardee" /> The [[Indian National Science Academy]] elected him as their fellow in 1984 and the [[National Academy of Sciences, India]] followed INSA with their fellowship in 1991.<ref name="NASI fellows">{{cite web | url=http://www.nasi.org.in/fellows.asp?RsFilter=D | title=NASI fellows | publisher=National Academy of Sciences, India | date=2016 | access-date=22 September 2016}}</ref> He was also elected by the Indian Society for Parasitology as a fellow in 1993.<ref name="Fellows - ISP">{{cite web | url=http://www.parasitologyindia.org/fellows.htm | title=Fellows - ISP | publisher=Indian Society for Parasitology | date=2016 | access-date=21 September 2016 | archive-url=https://web.archive.org/web/20141213195132/http://www.parasitologyindia.org/fellows.htm | archive-date=13 December 2014 | url-status=dead | df=dmy-all }}</ref> | ||
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* [[Central Institute of Medicinal and Aromatic Plants]] | * [[Central Institute of Medicinal and Aromatic Plants]] | ||
* [[Walter Reed Army Institute of Research]] | * [[Walter Reed Army Institute of Research]] | ||
== Notes == | == Notes == | ||
| Line 49: | Line 49: | ||
{{DEFAULTSORT:Dutta, Guru Prakash}} | {{DEFAULTSORT:Dutta, Guru Prakash}} | ||
[[Category:1933 births]] | |||
[[Category:2021 deaths]] | |||
[[Category:Recipients of the Shanti Swarup Bhatnagar Award in Biological Science]] | [[Category:Recipients of the Shanti Swarup Bhatnagar Award in Biological Science]] | ||
[[Category:Indian cell biologists]] | [[Category:Indian cell biologists]] | ||
[[Category:Indian immunologists]] | [[Category:Indian immunologists]] | ||
| Line 59: | Line 60: | ||
[[Category:Fellows of The National Academy of Sciences, India]] | [[Category:Fellows of The National Academy of Sciences, India]] | ||
[[Category:Council of Scientific and Industrial Research]] | [[Category:Council of Scientific and Industrial Research]] | ||
[[Category:20th-century Indian biologists]] | [[Category:20th-century Indian biologists]] | ||
[[Category:Scientists from Punjab, India]] | [[Category:Scientists from Punjab, India]] | ||
Latest revision as of 03:43, 14 August 2023
Dr. Guru Prakash Dutta | |
|---|---|
| Born | 19 November 1933 India |
| Died | 25 April 2021 (aged 87) |
| Nationality | Indian |
| Alma mater | Punjab University |
| Known for |
|
| Awards | 1976 Shanti Swarup Bhatnagar Prize |
| Scientific career | |
| Fields | Cell biology |
| Institutions | |
Guru Prakash Dutta (19 November 1933 - 25 April 2021) was an Indian cell biologist and immunologist, known for his contributions to the subjects of Experimental protozoology and Immunology.[1][2] His researches are reported to have assisted in the development of a number of anti-malarial drugs.[3] He was an elected fellow of the Indian National Science Academy, National Academy of Sciences, India and Indian Society of Parasitology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1976, for his contributions to biological sciences.[4]
Biography[edit | edit source]
Guru Prakash Dutta, after graduating in zoology in 1952 from DAV College, Jallandhar[5] of Punjab University, followed it up with an honors degree in 1955, a master's degree (MSc) in 1956 and a doctoral degree (PhD) in 1961 from the same institution.[3] He started his career as a lecturer at his alma mater in 1962 where he stayed till his move to Central Drug Research Institute (CDRI) in 1964; in between, he had a stint at National Institutes of Health, Bethesda as a post-doctoral fellow during 1962–63. He served CDRI for more than three decades and was a director's grade scientist at the time of his superannuation in 1993. Post his retirement, he served as an emeritus scientist of the Council of Scientific and Industrial Research at CDRI from 1994 to 1998 and as an honorary consultant on Malaria at the Central Institute of Medicinal and Aromatic Plants from 1998 to 2000.[3]
Dutta, whose researches on experimental protozoology assisted in a wider understanding of protozoa and its functional morphology, is known to have developed new techniques for the culture of those unicellular eukaryotic organisms and studied their metabolic and growth responses to physico-chemical factors, with special emphasis on Entamoeba histolytica, an anaerobic parasite which causes amoebiasis.[6] His work on the antimalarial drugs helped in the development of several fast-acting drugs and alpha/beta arteether, alpha and beta arteether, alpha and beta artelinate, dihydroartemisinin, pyronaridine, bulaquine and Tefenoquine are some of drugs developed with the assistance of his researches.[3][note 1]
Dutta's researches have been detailed in over 275 articles[7][8] and two books, Antimalarial Drug Development and Prophylaxis against Malaria and Experimental and Clinical Studies on Amoebiasis.[9] The International Review of Cytology of Academic Press has published five reviews, three on Cytochemistry and ultrastructure of Protozoa and two on Amoebiasis and ResearchGate, an online repository of scientific articles, has listed 130 of his papers.[10] He has been a collaborator for Walter Reed Army Institute of Research in two of their international programs on Malaria which ran between 1983 and 1994. He has also mentored 40 master's and doctoral scholars in their researches.[3]
Dutta received the degree of Doctor of Science from the Punjab University in 1973 and the Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards, for his contributions to biological sciences in 1976.[2] The Indian National Science Academy elected him as their fellow in 1984 and the National Academy of Sciences, India followed INSA with their fellowship in 1991.[11] He was also elected by the Indian Society for Parasitology as a fellow in 1993.[12]
See also[edit | edit source]
- Central Drug Research Institute
- Central Institute of Medicinal and Aromatic Plants
- Walter Reed Army Institute of Research
Notes[edit | edit source]
References[edit | edit source]
- ↑ "Obituary". Springer Link. Retrieved 12 August 2021.
- ↑ 2.0 2.1 "Brief Profile of the Awardee". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 19 September 2016.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 "Indian Fellow - G. P. Dutta". Indian National Science Academy. 2016. Retrieved 21 September 2016.
- ↑ "View Bhatnagar Awardees". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 19 September 2016.
- ↑ G. P. Dutta (September 1959). "Histochemical Studies of Herpetomonas muscarum" (PDF). Journal of Microscopical Science. 100 (3): 413–419.
- ↑ "Handbook of Shanti Swarup Bhatnagar Prize Winners" (PDF). Council of Scientific and Industrial Research. 1999. p. 36. Archived from the original (PDF) on 4 March 2016. Retrieved 19 September 2016.
- ↑ R. A. Vishwakarma; R. Mehrotra; R. Tripathi; G. P. Dutta (1992). "Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin". J. Nat. Prod. 55 (8): 1142–1144. doi:10.1021/np50086a018. PMID 1431937.
- ↑ Renu Tripathi; Charles W Jefford; G P Dutta (August 2006). "Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo". Parasitology. 133 (1): 1–9. doi:10.1017/s0031182006009905. PMID 16764736.
- ↑ G. P. Dutta (1982). Experimental and Clinical Studies on Amoebiasis. Tata-McGraw Hill. p. 390. ISBN 978-0070963955.
- ↑ "G P Dutta on ResearchGate". Author search. 2016. Retrieved 21 September 2016.
- ↑ "NASI fellows". National Academy of Sciences, India. 2016. Retrieved 22 September 2016.
- ↑ "Fellows - ISP". Indian Society for Parasitology. 2016. Archived from the original on 13 December 2014. Retrieved 21 September 2016.