File:Fpubh-08-00383-g004.jpg

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DescriptionFpubh-08-00383-g004.jpg
English: The association between SARS-CoV-2 and the Renin-Angiotensin-Aldosterone System (RAAS). SARS-CoV-2 binds to ACE2 receptor and enters into the cell. It has been hypothesized that this process leads to down-regulation of surface ACE2, resulting in unopposed angiotensin II buildup and activity, leading to a pro-inflammatory cascade. Alternative hypotheses are further described in the text. The uncertainties regarding the role of ACE-Is and ARBs in COVID-19 are also discussed. Ang, angiotensin; ACE, angiotensin-converting enzyme; AT1, angiotensin II type 1
Date
Source

Chams N, Chams S, Badran R, Shams A, Araji A, Raad M, Mukhopadhyay S, Stroberg E, Duval EJ, Barton LM and Hajj Hussein I (2020) COVID-19: A Multidisciplinary Review. Front. Public Health 8:383.

https://doi.org/10.3389/fpubh.2020.00383
Author Nour Chams, Sana Chams, Reina Badran, Ali Shams, Abdallah Araji, Mohamad Raad, Sanjay Mukhopadhyay, Edana Stroberg, Eric J. Duval, Lisa M. Barton, and Inaya Hajj Hussein

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Captions

The association between SARS-CoV-2 and the Renin-Angiotensin-Aldosterone System (RAAS).

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29 July 2020

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957 × 557 (285 KB)smartcommons>Guest2625Uploaded a work by Nour Chams, Sana Chams, Reina Badran, Ali Shams, Abdallah Araji, Mohamad Raad, Sanjay Mukhopadhyay, Edana Stroberg, Eric J. Duval, Lisa M. Barton, and Inaya Hajj Hussein from Chams N, Chams S, Badran R, Shams A, Araji A, Raad M, Mukhopadhyay S, Stroberg E, Duval EJ, Barton LM and Hajj Hussein I (2020) COVID-19: A Multidisciplinary Review. Front. Public Health 8:383. https://doi.org/10.3389/fpubh.2020.00383 with UploadWizard

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