Nayeem is a variant spelling of the name Naim, a male given name and family name.
- M Abu Nayeem (IT Freelancer), Owner - CreateSo Tech
- Nayeem (actor), Bangladeshi film actor of the 1990s
- Mohammad Nayeem Hasan, Bangladesh cricketer
- Nabiul Islam Nayeem, Bangladesh cricketer
- Syed Nayeemuddin, captain and later coach of India national football team
- Mohammed Nayeemuddin (died August 8, 2016)), Gangster, Naxal leader, and alleged criminal
- FS Nayeem, TV actor, husband of Nadia Ahmed