Hemendra Nath Chatterjee was an Indian scientist from West Bengal, who first formulated and demonstrated the effectiveness of Orally Rehydrated Saline (ORS) for diarrhea management. His paper regarding this finding was published in Lancet of November 1953. In that paper he states that Avomine can stop vomiting during cholera and then oral rehydration is possible. The formulation of the fluid replacement solution was 4 g of sodium chloride, 25 g of glucose and 1000 ml of water.[1][2]