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{{short description|Indian Cell and Developmental Biologist}}
{{short description|Indian Cell and Developmental Biologist}}
[[File:Dr. Jyotsna Dhawan.tif|thumb]]
[[File:Dr. Jyotsna Dhawan.tif|thumb|Jyotsna Dhawan]]
'''Jyotsna Dhawan''' is an Indian Cell and Developmental Biologist, Emeritus Scientist at [[Centre for Cellular and Molecular Biology]]<ref name="ccmb">{{cite web |url=https://www.ccmb.res.in/People/Research-Group/Jyotsna-Dhawan |title=Jyotsna Dhawan |website=CCMB |accessdate=14 July 2020}}</ref><ref name="frontiers">{{cite web |url=https://loop.frontiersin.org/people/125221/bio|title=Jyotsna Dhawan |website=Loop - Frontiers |accessdate=14 July 2020}}</ref> and Visiting Professor, [[Institute for Stem Cell Science and Regenerative Medicine]] (inStem).<ref name="ccmb" /><ref name="lab">{{cite web |title=Prof. Jyotsna Dhawan |url=https://quiescentmusclab.weebly.com/people.html |website=Muscle stem cell Lab |accessdate=14 July 2020}}</ref> Dhawan's research has focused on adult stem cell function and skeletal muscle regeneration.<ref name="ccmb" /><ref name="frontiers" /><ref name="lab" /><ref name="tdu">{{cite web |title=Dr. Jyotsna Dhawan |url=http://tdu.edu.in/governance/jyotsna-dhawan/ |website=The University of Trans-Disciplinary Health Sciences and Technology |accessdate=24 July 2020}} </ref> Dhawan is the current (2019-2021) President of the Indian Society for Cell Biology<ref name="frontiers"/><ref name="ISCB">{{cite web |title=Executive Committee Members of the Society |url=http://iscb.org.in/homepage.htm |website=ISCB |accessdate=24 July 2020}}</ref> and the Indian Society of Developmental Biologists (2017-2020).<ref name="frontiers" /><ref>{{cite web |title=Office Bearers |url=http://www.devbioindia.org/index.php?page=office_bearers&lid=130 |website=InSDB: Indian Society for Developmental Biologists |accessdate=24 July 2020}}</ref> Dhawan was elected as a fellow to the Indian National Science Academy in 2019.<ref name="frontiers" /><ref>{{cite web |title=Indian Fellow |url=http://www.insaindia.res.in/detail/P20-1835 |website=Indian National Science Academy |accessdate=24 July 2020}}</ref>
'''Jyotsna Dhawan''' is an Indian Cell and Developmental Biologist, Emeritus Scientist at [[Centre for Cellular and Molecular Biology]]<ref name="ccmb">{{cite web |url=https://www.ccmb.res.in/People/Research-Group/Jyotsna-Dhawan |title=Jyotsna Dhawan |website=CCMB |accessdate=14 July 2020}}</ref><ref name="frontiers">{{cite web |url=https://loop.frontiersin.org/people/125221/bio|title=Jyotsna Dhawan |website=Loop - Frontiers |accessdate=14 July 2020}}</ref> and Visiting Professor, Institute for Stem Cell Science and Regenerative Medicine (inStem).<ref name="ccmb" /><ref name="lab">{{cite web |title=Prof. Jyotsna Dhawan |url=https://quiescentmusclab.weebly.com/people.html |website=Muscle stem cell Lab |accessdate=14 July 2020}}</ref> Dhawan's research has focused on adult stem cell function and skeletal muscle regeneration.<ref name="ccmb" /><ref name="frontiers" /><ref name="lab" /><ref name="tdu">{{cite web |title=Dr. Jyotsna Dhawan |url=http://tdu.edu.in/governance/jyotsna-dhawan/ |website=The University of Trans-Disciplinary Health Sciences and Technology |accessdate=24 July 2020 |archive-date=21 June 2020 |archive-url=https://web.archive.org/web/20200621110210/http://tdu.edu.in/governance/jyotsna-dhawan/ |url-status=dead }}</ref> Dhawan is the current (2019-2021) President of the Indian Society for Cell Biology<ref name="frontiers"/><ref name="ISCB">{{cite web |title=Executive Committee Members of the Society |url=http://iscb.org.in/homepage.htm |website=ISCB |accessdate=24 July 2020}}</ref> and the Indian Society of Developmental Biologists (2017–2020).<ref name="frontiers" /><ref>{{cite web |title=Office Bearers |url=http://www.devbioindia.org/index.php?page=office_bearers&lid=130 |website=InSDB: Indian Society for Developmental Biologists |accessdate=24 July 2020 |archive-date=25 July 2020 |archive-url=https://web.archive.org/web/20200725001658/http://www.devbioindia.org/index.php?page=office_bearers&lid=130 |url-status=dead }}</ref> Dhawan was elected as a fellow to the [[Indian National Science Academy]] in 2019.<ref name="frontiers" /><ref>{{cite web |title=Indian Fellow |url=http://www.insaindia.res.in/detail/P20-1835 |website=Indian National Science Academy |accessdate=24 July 2020}}</ref>


== Early life and education ==
== Early life and education ==
Dhawan's father [[Satish Dhawan]] was a faculty at the [[Indian Institute of Science]]<ref name="family">{{cite web |last1=S |first1=Deepika |last2=Ramaswamy |first2=Karthik |title=My Father, Satish Dhawan |url=https://connect.iisc.ac.in/2017/08/father-satish-dhawan/ |website=Connect with IISc |accessdate=24 July 2020}}</ref> and Dhawan's mother Nalini, was a cytogeneticist.<ref name="family" /> She completed her Masters in Botany from [[Delhi University]] in 1983.<ref name="ccmb" /><ref name="interview">{{cite web |last1=Jayaraj |first1=Nandita |last2=Dogra |first2=Aashima |title=Flexing muscle (stem cells) with Jyotsna |url=https://thelifeofscience.com/tm/2017/02/27/flexing-muscle-stem-cells-with-jyotsna/ |website=The Life of Science}}</ref> She contemplated quitting her master's degree however, a summer internship in yeast genetics at the Tata Institute of Fundamental Research, convinced her to pursue a PhD.<ref name="interview" /> She completed her PhD from [[Boston University]] in 1991.<ref name="ccmb" /><ref name="lab" /> She completed her postdoctoral training at [[Stanford University]] studying muscle stem cells and gene therapy in 1995.<ref name="ccmb" /><ref name="lab" />
Dhawan's father [[Satish Dhawan]] was a faculty at the [[Indian Institute of Science]]<ref name="family">{{cite web |last1=S |first1=Deepika |last2=Ramaswamy |first2=Karthik |title=My Father, Satish Dhawan |url=https://connect.iisc.ac.in/2017/08/father-satish-dhawan/ |website=Connect with IISc |accessdate=24 July 2020}}</ref> and Dhawan's mother Nalini, was a cytogeneticist.<ref name="family" /> She completed her master's in botany from [[Delhi University]] in 1983.<ref name="ccmb" /><ref name="interview">{{cite web |last1=Jayaraj |first1=Nandita |last2=Dogra |first2=Aashima |title=Flexing muscle (stem cells) with Jyotsna |url=https://thelifeofscience.com/tm/2017/02/27/flexing-muscle-stem-cells-with-jyotsna/ |website=The Life of Science|date=27 February 2017 }}</ref> She contemplated quitting her master's degree however, a summer internship in yeast genetics at the [[Tata Institute of Fundamental Research]], convinced her to pursue a PhD.<ref name="interview" /> She completed her PhD from [[Boston University]] in 1991.<ref name="ccmb" /><ref name="lab" /> She completed her postdoctoral training at [[Stanford University]] studying muscle stem cells and [[gene therapy]] in 1995.<ref name="ccmb" /><ref name="lab" />


== Career ==
== Career ==
Dhawan joined [[Centre for Cellular and Molecular Biology]] as faculty in 1996<ref name="lab" /> and started her lab studying the biology of muscle stem cells and muscle repair.  From 2009–2014, she helped set up the [[Institute for Stem Cell Science and Regenerative Medicine]] (inStem) in Bangalore and served as Senior Professor and Dean.<ref name="ccmb" /><ref name="lab" /> In 2014, she returned to [[Centre for Cellular and Molecular Biology]] and retained ties to InStem as a visiting professor and member of the advisory board.<ref name="ccmb" /><ref name="lab" /><ref name="tdu" />
Dhawan joined [[Centre for Cellular and Molecular Biology]] as faculty in 1996<ref name="lab" /> and started her lab studying the biology of muscle stem cells and muscle repair.  From 2009–2014, she helped set up the Institute for Stem Cell Science and Regenerative Medicine (inStem) in Bangalore and served as Senior Professor and Dean.<ref name="ccmb" /><ref name="lab" /> In 2014, she returned to [[Centre for Cellular and Molecular Biology]] and retained ties to InStem as a visiting professor and member of the advisory board.<ref name="ccmb" /><ref name="lab" /><ref name="tdu" />


Dhawan has been an active advocate for establishing India as a leader in biomedical research.<ref>{{Cite journal|url=https://www.cell.com/cell/abstract/S0092-8674(05)01226-2|title=Bioscience in India: Times Are Changing|first1=Jyotsna|last1=Dhawan|first2=Rajesh S.|last2=Gokhale|first3=Inder M.|last3=Verma|date=December 2, 2005|journal=Cell|volume=123|issue=5|pages=743–745|via=www.cell.com|doi=10.1016/j.cell.2005.11.018|pmid=16325565|doi-access=free}}</ref> She serves as the Scientist In Charge of [[Centre for Cellular and Molecular Biology]]’s iHub, an innovation space with an incubation center for biomedical startups<ref name="lab" /> and has served on several scientific review committees, scientific task forces and advisory boards at the national and institutional level.<ref name="frontiers" />  She has also been a part on the editorial board of Physiological Genomics, BBRC and [[Frontiers in Cell and Developmental Biology]].<ref name="frontiers" />
Dhawan has been an active advocate for establishing India as a leader in biomedical research.<ref>{{cite journal |last1=Dhawan |first1=Jyotsna |last2=Gokhale |first2=Rajesh S. |last3=Verma |first3=Inder M. |title=Bioscience in India: Times Are Changing |journal=Cell |date=December 2005 |volume=123 |issue=5 |pages=743–745 |doi=10.1016/j.cell.2005.11.018 |pmid=16325565 |doi-access=free }}</ref> She serves as the Scientist In Charge of [[Centre for Cellular and Molecular Biology]]’s iHub, an innovation space with an incubation center for biomedical startups<ref name="lab" /> and has served on several scientific review committees, scientific task forces and advisory boards at the national and institutional level.<ref name="frontiers" />  She has also been a part on the editorial board of Physiological Genomics, BBRC and [[Frontiers in Cell and Developmental Biology]].<ref name="frontiers" />


== Selected publications ==
== Selected publications ==
* Sirisha Cheedipudi, Deepika Puri, Amena Saleh, Hardik P. Gala, Mohammed Rumman, Malini S. Pillai, Prethish Sreenivas, Reety Arora, Jeeva Sellathurai, Henrik Daa Schrøder, Rakesh K. Mishra, Jyotsna Dhawan, A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene, Nucleic Acids Research, Volume 43, Issue 13, 27 July 2015, Pages 6236–6256<ref>{{Cite journal|last=Cheedipudi|first=Sirisha|last2=Puri|first2=Deepika|last3=Saleh|first3=Amena|last4=Gala|first4=Hardik P.|last5=Rumman|first5=Mohammed|last6=Pillai|first6=Malini S.|last7=Sreenivas|first7=Prethish|last8=Arora|first8=Reety|last9=Sellathurai|first9=Jeeva|last10=Schrøder|first10=Henrik Daa|last11=Mishra|first11=Rakesh K.|date=2015-07-27|title=A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene|url=https://academic.oup.com/nar/article/43/13/6236/2414227|journal=Nucleic Acids Research|language=en|volume=43|issue=13|pages=6236–6256|doi=10.1093/nar/gkv567|issn=0305-1048|doi-access=free}}</ref>
* {{cite journal |last1=Cheedipudi |first1=Sirisha |last2=Puri |first2=Deepika |last3=Saleh |first3=Amena |last4=Gala |first4=Hardik P. |last5=Rumman |first5=Mohammed |last6=Pillai |first6=Malini S. |last7=Sreenivas |first7=Prethish |last8=Arora |first8=Reety |last9=Sellathurai |first9=Jeeva |last10=Schrøder |first10=Henrik Daa |last11=Mishra |first11=Rakesh K. |last12=Dhawan |first12=Jyotsna |title=A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene |journal=Nucleic Acids Research |date=27 July 2015 |volume=43 |issue=13 |pages=6236–6256 |doi=10.1093/nar/gkv567 |pmid=26040698 |pmc=4513853 }}
 
* {{cite journal |last1=Krishna |first1=Srikar |last2=Nair |first2=Aparna |last3=Cheedipudi |first3=Sirisha |last4=Poduval |first4=Deepak |last5=Dhawan |first5=Jyotsna |last6=Palakodeti |first6=Dasaradhi |last7=Ghanekar |first7=Yashoda |title=Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata |journal=Nucleic Acids Research |date=1 January 2013 |volume=41 |issue=1 |pages=599–616 |doi=10.1093/nar/gks1020 |pmid=23166307 |pmc=3592418 }}
* Srikar Krishna, Aparna Nair, Sirisha Cheedipudi, Deepak Poduval, Jyotsna Dhawan, Dasaradhi Palakodeti, Yashoda Ghanekar, Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata, Nucleic Acids Research, Volume 41, Issue 1, 1 January 2013, Pages 599–616<ref>{{Cite journal|last=Krishna|first=Srikar|last2=Nair|first2=Aparna|last3=Cheedipudi|first3=Sirisha|last4=Poduval|first4=Deepak|last5=Dhawan|first5=Jyotsna|last6=Palakodeti|first6=Dasaradhi|last7=Ghanekar|first7=Yashoda|date=2013-01-01|title=Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata|url=https://academic.oup.com/nar/article/41/1/599/1146895|journal=Nucleic Acids Research|language=en|volume=41|issue=1|pages=599–616|doi=10.1093/nar/gks1020|issn=0305-1048|doi-access=free}}</ref>
* {{cite journal |last1=Sebastian |first1=S. |last2=Sreenivas |first2=P. |last3=Sambasivan |first3=R. |last4=Cheedipudi |first4=S. |last5=Kandalla |first5=P. |last6=Pavlath |first6=G. K. |last7=Dhawan |first7=J. |title=MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation |journal=Proceedings of the National Academy of Sciences |date=24 March 2009 |volume=106 |issue=12 |pages=4719–4724 |doi=10.1073/pnas.0807136106 |pmid=19264965 |pmc=2651835 |bibcode=2009PNAS..106.4719S |doi-access=free }}
 
* MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation Soji Sebastian, Prethish Sreenivas, Ramkumar Sambasivan, Sirisha Cheedipudi, Prashanth Kandalla, Grace K. Pavlath, Jyotsna Dhawan Proceedings of the National Academy of Sciences Mar 2009, 106 (12) 4719–4724; DOI: 10.1073/pnas.0807136106<ref>{{Cite journal|last=Sebastian|first=Soji|last2=Sreenivas|first2=Prethish|last3=Sambasivan|first3=Ramkumar|last4=Cheedipudi|first4=Sirisha|last5=Kandalla|first5=Prashanth|last6=Pavlath|first6=Grace K.|last7=Dhawan|first7=Jyotsna|date=2009-03-24|title=MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation|url=https://www.pnas.org/content/106/12/4719|journal=Proceedings of the National Academy of Sciences|language=en|volume=106|issue=12|pages=4719–4724|doi=10.1073/pnas.0807136106|issn=0027-8424|pmid=19264965|doi-access=free}}</ref>


==References==
==References==

Latest revision as of 15:12, 22 December 2025


File:Dr. Jyotsna Dhawan.tif Jyotsna Dhawan is an Indian Cell and Developmental Biologist, Emeritus Scientist at Centre for Cellular and Molecular Biology[1][2] and Visiting Professor, Institute for Stem Cell Science and Regenerative Medicine (inStem).[1][3] Dhawan's research has focused on adult stem cell function and skeletal muscle regeneration.[1][2][3][4] Dhawan is the current (2019-2021) President of the Indian Society for Cell Biology[2][5] and the Indian Society of Developmental Biologists (2017–2020).[2][6] Dhawan was elected as a fellow to the Indian National Science Academy in 2019.[2][7]

Early life and education[edit | edit source]

Dhawan's father Satish Dhawan was a faculty at the Indian Institute of Science[8] and Dhawan's mother Nalini, was a cytogeneticist.[8] She completed her master's in botany from Delhi University in 1983.[1][9] She contemplated quitting her master's degree however, a summer internship in yeast genetics at the Tata Institute of Fundamental Research, convinced her to pursue a PhD.[9] She completed her PhD from Boston University in 1991.[1][3] She completed her postdoctoral training at Stanford University studying muscle stem cells and gene therapy in 1995.[1][3]

Career[edit | edit source]

Dhawan joined Centre for Cellular and Molecular Biology as faculty in 1996[3] and started her lab studying the biology of muscle stem cells and muscle repair. From 2009–2014, she helped set up the Institute for Stem Cell Science and Regenerative Medicine (inStem) in Bangalore and served as Senior Professor and Dean.[1][3] In 2014, she returned to Centre for Cellular and Molecular Biology and retained ties to InStem as a visiting professor and member of the advisory board.[1][3][4]

Dhawan has been an active advocate for establishing India as a leader in biomedical research.[10] She serves as the Scientist In Charge of Centre for Cellular and Molecular Biology’s iHub, an innovation space with an incubation center for biomedical startups[3] and has served on several scientific review committees, scientific task forces and advisory boards at the national and institutional level.[2] She has also been a part on the editorial board of Physiological Genomics, BBRC and Frontiers in Cell and Developmental Biology.[2]

Selected publications[edit | edit source]

  • Cheedipudi, Sirisha; Puri, Deepika; Saleh, Amena; Gala, Hardik P.; Rumman, Mohammed; Pillai, Malini S.; Sreenivas, Prethish; Arora, Reety; Sellathurai, Jeeva; Schrøder, Henrik Daa; Mishra, Rakesh K.; Dhawan, Jyotsna (27 July 2015). "A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene". Nucleic Acids Research. 43 (13): 6236–6256. doi:10.1093/nar/gkv567. PMC 4513853. PMID 26040698.
  • Krishna, Srikar; Nair, Aparna; Cheedipudi, Sirisha; Poduval, Deepak; Dhawan, Jyotsna; Palakodeti, Dasaradhi; Ghanekar, Yashoda (1 January 2013). "Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata". Nucleic Acids Research. 41 (1): 599–616. doi:10.1093/nar/gks1020. PMC 3592418. PMID 23166307.
  • Sebastian, S.; Sreenivas, P.; Sambasivan, R.; Cheedipudi, S.; Kandalla, P.; Pavlath, G. K.; Dhawan, J. (24 March 2009). "MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation". Proceedings of the National Academy of Sciences. 106 (12): 4719–4724. Bibcode:2009PNAS..106.4719S. doi:10.1073/pnas.0807136106. PMC 2651835. PMID 19264965.

References[edit | edit source]

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 "Jyotsna Dhawan". CCMB. Retrieved 14 July 2020.
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 "Jyotsna Dhawan". Loop - Frontiers. Retrieved 14 July 2020.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 "Prof. Jyotsna Dhawan". Muscle stem cell Lab. Retrieved 14 July 2020.
  4. ↑ 4.0 4.1 "Dr. Jyotsna Dhawan". The University of Trans-Disciplinary Health Sciences and Technology. Archived from the original on 21 June 2020. Retrieved 24 July 2020.
  5. ↑ "Executive Committee Members of the Society". ISCB. Retrieved 24 July 2020.
  6. ↑ "Office Bearers". InSDB: Indian Society for Developmental Biologists. Archived from the original on 25 July 2020. Retrieved 24 July 2020.
  7. ↑ "Indian Fellow". Indian National Science Academy. Retrieved 24 July 2020.
  8. ↑ 8.0 8.1 S, Deepika; Ramaswamy, Karthik. "My Father, Satish Dhawan". Connect with IISc. Retrieved 24 July 2020.
  9. ↑ 9.0 9.1 Jayaraj, Nandita; Dogra, Aashima (27 February 2017). "Flexing muscle (stem cells) with Jyotsna". The Life of Science.
  10. ↑ Dhawan, Jyotsna; Gokhale, Rajesh S.; Verma, Inder M. (December 2005). "Bioscience in India: Times Are Changing". Cell. 123 (5): 743–745. doi:10.1016/j.cell.2005.11.018. PMID 16325565.
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