Amitabha Chattopadhyay: Difference between revisions

Prof. Chattopadhyay’s work is focused on monitoring organization, dynamics and function of [[Biological membrane|biological membranes]] in healthy and diseased conditions. His group has developed and applied novel, innovative and sensitive techniques based on [[fluorescence spectroscopy]] for monitoring solvent relaxation in membranes, membrane-mimetic media, and proteins. Prof. Chattopadhyay’s group focuses on the role of membrane cholesterol in regulating the organization, dynamics and function of [[G protein-coupled receptor|G protein-coupled receptors]] (GPCRs), Pioneering work from his group showed that membrane cholesterol is necessary for the function and organization of GPCRs. In addition, his work has provided novel insight in the role of membrane cholesterol in the entry of pathogens into host cells. He has used fluorescence-based microscopic approaches such as [[Fluorescence recovery after photobleaching|Fluorescence Recovery After Photobleaching]] (FRAP), [[Fluorescence correlation spectroscopy|Fluorescence Correlation Spectroscopy]] (FCS), and [[Fluorescence Resonance Energy Transfer]] (FRET) to provide useful insight into organization, dynamics and function of membrane receptors.