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'''Handigodu syndrome''' is a rare and painful [[osteoarthritis|osteoarthritic]] disorder [[endemic (epidemiology)|endemic]] to the [[Malnad]] region in the state of [[Karnataka]], [[India]].<ref name="ende">{{cite news|url=http://www.hindu.com/2005/09/13/stories/2005091309130100.htm|archive-url=https://web.archive.org/web/20051128061237/http://www.hindu.com/2005/09/13/stories/2005091309130100.htm|url-status=dead|archive-date=2005-11-28|author=Divya Ramamurthi|title=This small family lives in painful isolation|access-date=2007-05-30|location=Chennai, India|work=[[The Hindu]]|date=2005-09-13}}</ref> Also known as ''Handigodu Joint Disease'', it derives its name from the village of ''Handigodu'' in the [[Sagara, India|Sagara]] [[taluk]] of the [[Shimoga district]] of [[Karnataka]] where it was first noticed. This disease currently has no cure.<ref name="nocure">{{cite web|url=http://www.deccanherald.com/Content/May192007/state200705182509.asp|author=Veerendra P M|title=CM juggernaut mows down another taboo|work=Online webpage of the Deccan Herald, dated 2007-05-19|publisher=2007, The Printers (Mysore) Private Ltd.|access-date=2007-05-30 |archive-url = https://web.archive.org/web/20070521060127/http://www.deccanherald.com/Content/May192007/state200705182509.asp <!-- Bot retrieved archive --> |archive-date = 2007-05-21}}</ref> Scientifically it is termed as ''Endemic Familial [[Arthritis]] of [[Malnad]]''.<ref name="maln">{{cite web|url=http://www.hinduonnet.com/thehindu/2002/01/18/stories/2002011800720300.htm|author=Pramod Mellegatti|title=A disease that has left many crippled|work=Online webpage of the Hindu, dated 2002-01-18|publisher=2002, The Hindu|access-date=2007-05-30}}</ref> Since the day it was discovered, it has claimed over 1000 lives and has left many people crippled.<ref name="outl">{{cite web|url=http://www.outlookindia.com/mad.asp?sid=&fodname=19990118&fname=Difference.htm&synopsis=Handigodu+syndrome|author=B. R. Srikanth|title=Helping Handigodu Battle Its Unique Malady|work=Online webpage of the Outlook, 1999-01-18|publisher=© Outlook Publishing (India) Private Limited|access-date=2007-05-30|url-status=dead|archive-url=https://web.archive.org/web/20110611032651/http://www.outlookindia.com/mad.asp?sid=&fodname=19990118&fname=Difference.htm&synopsis=Handigodu+syndrome|archive-date=2011-06-11}}</ref> Apart from Sagara [[taluk]], the disease has also been reported from the [[Koppa India|Koppa]], [[Narasimharajapura]] and [[Sringeri]] [[taluk]]s of [[Chikkamagaluru district]].<ref name="maln"/> | '''Handigodu syndrome''' is a rare and painful [[osteoarthritis|osteoarthritic]] disorder [[endemic (epidemiology)|endemic]] to the [[Malnad]] region in the state of [[Karnataka]], [[India]].<ref name="ende">{{cite news|url=http://www.hindu.com/2005/09/13/stories/2005091309130100.htm|archive-url=https://web.archive.org/web/20051128061237/http://www.hindu.com/2005/09/13/stories/2005091309130100.htm|url-status=dead|archive-date=2005-11-28|author=Divya Ramamurthi|title=This small family lives in painful isolation|access-date=2007-05-30|location=Chennai, India|work=[[The Hindu]]|date=2005-09-13}}</ref> Also known as ''Handigodu Joint Disease'', it derives its name from the village of ''Handigodu'' in the [[Sagara, India|Sagara]] [[taluk]] of the [[Shimoga district]] of [[Karnataka]] where it was first noticed. This disease currently has no cure.<ref name="nocure">{{cite web|url=http://www.deccanherald.com/Content/May192007/state200705182509.asp|author=Veerendra P M|title=CM juggernaut mows down another taboo|work=Online webpage of the Deccan Herald, dated 2007-05-19|publisher=2007, The Printers (Mysore) Private Ltd.|access-date=2007-05-30 |archive-url = https://web.archive.org/web/20070521060127/http://www.deccanherald.com/Content/May192007/state200705182509.asp <!-- Bot retrieved archive --> |archive-date = 2007-05-21}}</ref> Scientifically it is termed as ''Endemic Familial [[Arthritis]] of [[Malnad]]''.<ref name="maln">{{cite web|url=http://www.hinduonnet.com/thehindu/2002/01/18/stories/2002011800720300.htm|archive-url=https://web.archive.org/web/20021101022851/http://www.hinduonnet.com/thehindu/2002/01/18/stories/2002011800720300.htm|url-status=usurped|archive-date=1 November 2002|author=Pramod Mellegatti|title=A disease that has left many crippled|work=Online webpage of the Hindu, dated 2002-01-18|publisher=2002, The Hindu|access-date=2007-05-30}}</ref> Since the day it was discovered, it has claimed over 1000 lives and has left many people crippled.<ref name="outl">{{cite web|url=http://www.outlookindia.com/mad.asp?sid=&fodname=19990118&fname=Difference.htm&synopsis=Handigodu+syndrome|author=B. R. Srikanth|title=Helping Handigodu Battle Its Unique Malady|work=Online webpage of the Outlook, 1999-01-18|publisher=© Outlook Publishing (India) Private Limited|access-date=2007-05-30|url-status=dead|archive-url=https://web.archive.org/web/20110611032651/http://www.outlookindia.com/mad.asp?sid=&fodname=19990118&fname=Difference.htm&synopsis=Handigodu+syndrome|archive-date=2011-06-11}}</ref> Apart from Sagara [[taluk]], the disease has also been reported from the [[Koppa India|Koppa]], [[Narasimharajapura]] and [[Sringeri]] [[taluk]]s of [[Chikkamagaluru district]].<ref name="maln"/> | ||
==Symptoms== | ==Symptoms and signs== | ||
Symptoms of the disease are an acute pain and swelling in the hips and knee joints. Some of the other characteristics of this disease are [[dwarfism]] from birth, [[deformity|deformation]] of the limbs after age seven and death as early as between 25 and 30 years or even younger.<ref name="outl"/> Depending on the mobility of the affected patients, the disease has been identified with three severities: in mild to moderate cases, the patient is able to walk with difficulty, in severe cases mobility is very restricted, whereas in acute cases the limbs are bent and badly crippled making the patients crawl.<ref name="maln"/> | Symptoms of the disease are an acute pain and swelling in the hips and knee joints. Some of the other characteristics of this disease are [[dwarfism]] from birth, [[deformity|deformation]] of the limbs after age seven and death as early as between 25 and 30 years or even younger.<ref name="outl"/> Depending on the mobility of the affected patients, the disease has been identified with three severities: in mild to moderate cases, the patient is able to walk with difficulty, in severe cases mobility is very restricted, whereas in acute cases the limbs are bent and badly crippled making the patients crawl.<ref name="maln"/> | ||
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Handigodu syndrome was first noticed by H M Chandrashekhar in the village of Handigodu during the years 1974-75.<ref name="outl"/> Four patients who complained of severe joint and hip pain were admitted to the General Hospital at [[Sagara, India|Sagar]]. The doctors who could not diagnose the problem attributed the pain to some [[neurological]] disorder.<ref name="maln"/> Seeking advice on this disease, a team of experts led by K. S. Mani, a [[neurologist]] from [[NIMHANS]], [[Bangalore]] visited the region.<ref name="maln"/> After examining the patients, they ruled out any neurological disorder and implied that the pain was due to a bone and joint disorder.{{citation needed|date=November 2020}} | Handigodu syndrome was first noticed by H M Chandrashekhar in the village of Handigodu during the years 1974-75.<ref name="outl"/> Four patients who complained of severe joint and hip pain were admitted to the General Hospital at [[Sagara, India|Sagar]]. The doctors who could not diagnose the problem attributed the pain to some [[neurological]] disorder.<ref name="maln"/> Seeking advice on this disease, a team of experts led by K. S. Mani, a [[neurologist]] from [[NIMHANS]], [[Bangalore]] visited the region.<ref name="maln"/> After examining the patients, they ruled out any neurological disorder and implied that the pain was due to a bone and joint disorder.{{citation needed|date=November 2020}} | ||
==Society== | ==Society and culture== | ||
A subsistence allowance is provided to the patients by the [[Government of Karnataka]] from the fund reserved for the physically challenged. Assistance has also been provided to construct houses for them. A special treatment unit has been set up in the Government Hospital at Sagar with an [[ambulance]] provided to shift the affected patients to the hospital.<ref name="outl"/> | A subsistence allowance is provided to the patients by the [[Government of Karnataka]] from the fund reserved for the physically challenged. Assistance has also been provided to construct houses for them. A special treatment unit has been set up in the Government Hospital at Sagar with an [[ambulance]] provided to shift the affected patients to the hospital.<ref name="outl"/> | ||