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Perdur Radhakantha Adiga: Difference between revisions
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P. R. Adiga, born on 5 May 1935 at [[Barkur]], a small hamlet in [[Udupi district]] of the south Indian state of [[Karnataka]] as one among the ten children of his parents, did his early schooling at local schools and earned a master's degree in biochemistry from the [[University of Kerala]] in the neighboring state.<ref name="P. R. Adiga (1935–2006)">{{Cite web |url=http://www.iisc.ernet.in/currsci/dec102006/1573.pdf |title=P. R. Adiga (1935–2006) |last=N. Appaji Rao |date=2006 |publisher=Current Science |pages=1573–1574}}</ref> Subsequently, he joined the [[Indian Institute of Science]] as a research associate and pursued his doctoral studies under the guidance of P. S. Sarma, who headed the department of biochemistry, to secure the degree in 1963. He spent his entire career at IISc, holding various positions as that of an assistant professor, associate professor and professor. He also chaired the erstwhile ''Centre for Reproductive Biology and Molecular Endocrinology''{{Refn|group=note|present-day Department of Molecular Reproduction, Development and Genetics}} at the institute.<ref name="Deceased fellow" /> Post retirement, he continued his association with IISc as an [[Indian National Science Academy|INSA]] Senior scientist.<ref name="INSA Senior Scientist" /> | P. R. Adiga, born on 5 May 1935 at [[Barkur]], a small hamlet in [[Udupi district]] of the south Indian state of [[Karnataka]] as one among the ten children of his parents, did his early schooling at local schools and earned a master's degree in biochemistry from the [[University of Kerala]] in the neighboring state.<ref name="P. R. Adiga (1935–2006)">{{Cite web |url=http://www.iisc.ernet.in/currsci/dec102006/1573.pdf |title=P. R. Adiga (1935–2006) |last=N. Appaji Rao |date=2006 |publisher=Current Science |pages=1573–1574}}</ref> Subsequently, he joined the [[Indian Institute of Science]] as a research associate and pursued his doctoral studies under the guidance of P. S. Sarma, who headed the department of biochemistry, to secure the degree in 1963. He spent his entire career at IISc, holding various positions as that of an assistant professor, associate professor and professor. He also chaired the erstwhile ''Centre for Reproductive Biology and Molecular Endocrinology''{{Refn|group=note|present-day Department of Molecular Reproduction, Development and Genetics}} at the institute.<ref name="Deceased fellow" /> Post retirement, he continued his association with IISc as an [[Indian National Science Academy|INSA]] Senior scientist.<ref name="INSA Senior Scientist" /> | ||
Adiga's early researches were focused on the growth and intermediary metabolism of fungi and insects and how they were impacted by the trace elements and metal toxicity.<ref name="P. R. Adiga (1935–2006)" /> His work on ''[[Lathyrus sativus]]'', commonly known as grass pea, revealed that [[Oxalyldiaminopropionic acid|N-oxalyl-diaminopropionic acid]], a neurotoxin present in the plant caused the neurological disorder of [[neurolathyrism]] in humans.<ref name="P. R. Adiga (1935–2006)" /> He was also credited with the discovery of [[Homoarginine]], an [[amino acid]] derivative, found in ''Lathyrus sativus''.<ref name="Deceased fellow" /> Later, he worked on vitamin-carrying proteins which demonstrated how the proteins carried vitamins such as [[thiamin]] and [[riboflavin]] to the foetus and his experiments on rodents showed antibodies generated during pregnancy might cause its termination.<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=23 February 2017 | archive-url=https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf | archive-date=4 March 2016 | url-status=dead }}</ref> He documented his researches by way of several articles in peer-reviewed journals<ref name="On ResearchGate">{{Cite web |url=https://www.researchgate.net/ | Adiga's early researches were focused on the growth and intermediary metabolism of fungi and insects and how they were impacted by the trace elements and metal toxicity.<ref name="P. R. Adiga (1935–2006)" /> His work on ''[[Lathyrus sativus]]'', commonly known as grass pea, revealed that [[Oxalyldiaminopropionic acid|N-oxalyl-diaminopropionic acid]], a neurotoxin present in the plant caused the neurological disorder of [[neurolathyrism]] in humans.<ref name="P. R. Adiga (1935–2006)" /> He was also credited with the discovery of [[Homoarginine]], an [[amino acid]] derivative, found in ''Lathyrus sativus''.<ref name="Deceased fellow" /> Later, he worked on vitamin-carrying proteins which demonstrated how the proteins carried vitamins such as [[thiamin]] and [[riboflavin]] to the foetus and his experiments on rodents showed antibodies generated during pregnancy might cause its termination.<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=23 February 2017 | archive-url=https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf | archive-date=4 March 2016 | url-status=dead }}</ref> He documented his researches by way of several articles in peer-reviewed journals<ref name="On ResearchGate">{{Cite web |url=https://www.researchgate.net/search/publication?q=Perdur%2BRadhakantha%2BAdiga |title=On ResearchGate |date=2016 }}</ref>{{Refn|group=note|Please see ''Selected bibliography'' section}} and the online article repository of the [[Indian Academy of Sciences]] has listed 192 of them.<ref name="Browse by Fellow">{{Cite web |url=http://repository.ias.ac.in/view/fellows/Adiga=3APerdur_Radhakantha=3A=3A.html |title=Browse by Fellow |date=2016 |publisher=Indian Academy of Sciences}}</ref> He edited the book, ''Perspectives in Primate Reproductive Biology''<ref name="Perspectives In Primate Reproductive Biology">{{Cite book |url=http://library.kyu.ac.ug/cgi-bin/koha/opac-detail.pl?biblionumber=39214 |title=Perspectives In Primate Reproductive Biology |author1=N.R. Moudgal|author2=K. Yoshinaga|author3=A.J. Rao|author4=P.R. Adiga |publisher=Wiley Eastern |year=1991 |isbn=8122403182 |page=364}}</ref> and contributed chapters to many books published by others;<ref name="Symposium2009">{{cite book|author=CIBA Foundation Symposium|title=Molecular Biology of Egg Maturation|url=https://books.google.com/books?id=DQUL_kG9c3EC&pg=PA130|date=14 September 2009|publisher=John Wiley & Sons|isbn=978-0-470-71849-0|pages=130–}}</ref><ref name="Gupta2012">{{cite book|author=Satish Kumar Gupta|title=Reproductive Immunology|url=https://books.google.com/books?id=bMjrCAAAQBAJ&pg=PA344|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4197-0|pages=344–}}</ref><ref name="Staff1999">{{cite book|author=International Plant Genetic Resources Institute Staff|title=Lathyrus Genetic Resources Network|url=https://books.google.com/books?id=4Am21L7nykgC&pg=PA63|date=1 December 1999|publisher=Bioversity International|isbn=978-92-9043-394-1|pages=63–}}</ref><ref name="GalstonSmith2012">{{cite book|author1=Arthur W. Galston|author2=T.A. Smith|author3=P. R. Adiga, G. L. Prasad|title=Polyamines in Plants|url=https://books.google.com/books?id=ckLvCAAAQBAJ|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-009-5171-6|chapter=Biosynthesis and regulation of polyamines in higher plants}}</ref> his work has been cited by a number of authors and researchers.<ref name="Dakshinamurti1994">{{cite book|author=Krishnamurti Dakshinamurti|title=Vitamin Receptors: Vitamins as Ligands in Cell Communication - Metabolic Indicators|url=https://books.google.com/books?id=RbGkNpRqZyoC&pg=PA173|date=21 July 1994|publisher=Cambridge University Press|isbn=978-0-521-39280-8|pages=173–}}</ref><ref name="GhoseGhosh2003">{{cite book|author1=Tarun K. Ghose|author2=Purnendu Ghosh|title=Biotechnology in India II|url=https://books.google.com/books?id=NfhsCQAAQBAJ&pg=PA213|date=3 July 2003|publisher=Springer|isbn=978-3-540-36466-5|pages=213–}}</ref><ref name="SlocumFlores1991">{{cite book|author1=Robert D. Slocum|author2=Hector E. Flores|title=Biochemistry and Physiology of Polyamines in Plants|url=https://archive.org/details/biochemistryphys00sloc|url-access=registration|date=20 December 1991|publisher=CRC Press|isbn=978-0-8493-6865-3|pages=[https://archive.org/details/biochemistryphys00sloc/page/21 21]–}}</ref> He was also associated with two journals, ''[[Journal of Biosciences]]'' and ''[[Molecular and Cellular Endocrinology]]'' as a member of their editorial boards.<ref name="Deceased fellow" /> | ||
Adiga died on 13 September 2006, at the age of 71, survived by his wife and two daughters.<ref name="P. R. Adiga (1935–2006)" /> | Adiga died on 13 September 2006, at the age of 71, survived by his wife and two daughters.<ref name="P. R. Adiga (1935–2006)" /> | ||
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=== Articles === | === Articles === | ||
* {{Cite journal |author1=Rao Saligame|author2=L. K. Ramachandran|author3=P. R. Adiga |title=The Isolation and Characterization of L-Homoarginine from Seeds of Lathyrus sativus |journal=Biochemistry |publication-date=1963 |volume=2 |issue=2 |pages=298–300 |doi=10.1021/bi00902a019 |year=1963}} | * {{Cite journal |author1=Rao Saligame|author2=L. K. Ramachandran|author3=P. R. Adiga |title=The Isolation and Characterization of L-Homoarginine from Seeds of Lathyrus sativus |journal=Biochemistry |publication-date=1963 |volume=2 |issue=2 |pages=298–300 |doi=10.1021/bi00902a019 |year=1963|pmid=13973060}} | ||
* {{Cite journal |author1=K. Sivarama Sastry|author2=Padmanaban Govindarajan|author3=P. R. Adiga|author4=P. S. Sarma |title=A sensitive microbiological assay procedure for determining magnesium in biological materials |journal=The Analyst |publication-date=1963 |volume=88 |issue=1048 |doi=10.1039/an9638800534 |year=1963 |page=534}} | * {{Cite journal |author1=K. Sivarama Sastry|author2=Padmanaban Govindarajan|author3=P. R. Adiga|author4=P. S. Sarma |title=A sensitive microbiological assay procedure for determining magnesium in biological materials |journal=The Analyst |publication-date=1963 |volume=88 |issue=1048 |doi=10.1039/an9638800534 |year=1963 |page=534|bibcode=1963Ana....88..534S}} | ||
* {{Cite journal |author1=P. R. Adiga|author2=P. S. Sarma|author3=Rao Saligame |title=The Isolation and Characterization of β-N-Oxalyl-L-α,β-Diaminopropionic Acid: A Neurotoxin from the Seeds of Lathyrus sativus |journal=Biochemistry |publication-date=1964 |volume=3 |issue=3 |pages=432–6 |doi=10.1021/bi00891a022 |pmid=14155110 |year=1964}} | * {{Cite journal |author1=P. R. Adiga|author2=P. S. Sarma|author3=Rao Saligame |title=The Isolation and Characterization of β-N-Oxalyl-L-α,β-Diaminopropionic Acid: A Neurotoxin from the Seeds of Lathyrus sativus |journal=Biochemistry |publication-date=1964 |volume=3 |issue=3 |pages=432–6 |doi=10.1021/bi00891a022 |pmid=14155110 |year=1964}} | ||
* {{Cite journal |author1=P. R. Adiga|author2=P. S. Sarma |title=Cysteine toxicity in Neurospora crassa: comparison of counteraction by sulphur amino acids and iron |journal=Indian | * {{Cite journal |author1=P. R. Adiga|author2=P. S. Sarma |title=Cysteine toxicity in Neurospora crassa: comparison of counteraction by sulphur amino acids and iron |journal=Indian Journal of Biochemistry |year=1970 |publication-date=1970 |volume=7 |issue=3 |pages=141–4|pmid=4252565 }} | ||
* {{Cite journal |author1=P. R. Adiga|author2=P. S. Sarma |title=The influence of ribonucleic acid & some of its structural constituents on metal toxicities in Corcyra cephalonica St |journal=Indian | * {{Cite journal |author1=P. R. Adiga|author2=P. S. Sarma |title=The influence of ribonucleic acid & some of its structural constituents on metal toxicities in Corcyra cephalonica St |journal=Indian Journal of Biochemistry |year=1970 |publication-date=1970 |volume=7 |issue=2 |pages=130–2|pmid=4248650 }} | ||
== See also == | == See also == | ||