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'''Vamsi K. Mootha''' is an [[India|Indian]]-born [[United States|American]] physician-scientist and [[computational biology|computational biologist]]. He is an Investigator of the [[Howard Hughes Medical Institute]], Professor of Systems Biology and Medicine at [[Harvard Medical School]], and is based in the Department of Molecular Biology at [[Massachusetts General Hospital]]. He is also an Institute Member of the [[Broad Institute]].<ref>http://mootha.med.harvard.edu/members_vm.html Mootha's biography</ref> | '''Vamsi K. Mootha''' is an [[India|Indian]]-born [[United States|American]] physician-scientist and [[computational biology|computational biologist]]. He is an Investigator of the [[Howard Hughes Medical Institute]], Professor of Systems Biology and Medicine at [[Harvard Medical School]], and is based in the Department of Molecular Biology at [[Massachusetts General Hospital]]. He is also an Institute Member of the [[Broad Institute]].<ref>http://mootha.med.harvard.edu/members_vm.html Mootha's biography</ref> | ||
His research group has made major contributions to mitochondrial and | His research group has made major contributions to mitochondrial biology and genomics. His group characterized the mammalian mitochondrial proteome and applied it to identify dozens of mitochondrial disease genes. His team used integrative genomics to identify the molecular components of the mitochondrial calcium uniporter. His team has also made the unexpected discovery that in animal models, low oxygen can alleviate mitochondrial disease. As a postdoctoral fellow he developed [[Gene Set Enrichment Analysis]], an algorithm that is widely used in genomics and has been implemented into a popular software tool. | ||
He is a 2004 recipient of the [[MacArthur Fellows Program|Macarthur Foundation "genius award"]]. He received the 2008 Daland Prize from the [[American Philosophical Society]] and a 2014 [[Padma Shri]] Award from the [[Republic of India]], the fourth highest civilian award given by the Indian government.<ref>[http://www.thehindu.com/news/national/padma-awards-for-7-persons-under-nri-pio-foreign-category/article5618199.ece Padma awards for 7 persons under NRI, PIO, foreign category - The Hindu<!-- Bot generated title -->]</ref><ref>{{Cite web|url=http://www.americanbazaaronline.com/2014/01/27/five-eminent-personalities-us-get-padma-awards-3-indian-americans/|title = Five eminent personalities from the US get Padma awards, 3 of them Indian Americans|date = 27 January 2014}}</ref><ref>[http://www.broad.mit.edu/about/bios/bio-mootha.html Vamsi Mootha | Broad Institute of MIT and Harvard<!-- Bot generated title -->]</ref><ref>[http://jem.rupress.org/cgi/content/full/205/6/1248 Vamsi Mootha: Taking an inventory of mitochondria<!-- Bot generated title -->]</ref> He was elected to the United States National Academy of Sciences in 2014. He also served on the Life Sciences jury for the [[Infosys Prize]] in 2017. | He is a 2004 recipient of the [[MacArthur Fellows Program|Macarthur Foundation "genius award"]]. He received the 2008 Daland Prize from the [[American Philosophical Society]] and a 2014 [[Padma Shri]] Award from the [[Republic of India]], the fourth highest civilian award given by the Indian government.<ref>[http://www.thehindu.com/news/national/padma-awards-for-7-persons-under-nri-pio-foreign-category/article5618199.ece Padma awards for 7 persons under NRI, PIO, foreign category - The Hindu<!-- Bot generated title -->]</ref><ref>{{Cite web|url=http://www.americanbazaaronline.com/2014/01/27/five-eminent-personalities-us-get-padma-awards-3-indian-americans/|title = Five eminent personalities from the US get Padma awards, 3 of them Indian Americans|date = 27 January 2014}}</ref><ref>[http://www.broad.mit.edu/about/bios/bio-mootha.html Vamsi Mootha | Broad Institute of MIT and Harvard<!-- Bot generated title -->]</ref><ref>[http://jem.rupress.org/cgi/content/full/205/6/1248 Vamsi Mootha: Taking an inventory of mitochondria<!-- Bot generated title -->]</ref> He was elected to the United States National Academy of Sciences in 2014 and the National Academy of Medicine in 2021. He also served on the Life Sciences jury for the [[Infosys Prize]] in 2017. | ||
Mootha graduated from Kelly High School in Beaumont, Texas. | Mootha graduated from Kelly High School in Beaumont, Texas. He received his [[Bachelor of Science|BS]] in Mathematical and Computational Science from [[Stanford University]] and his M.D. from [[Harvard University]]. He completed his internship and residency in internal medicine at [[Brigham and Women's Hospital]] in Boston, and then pursued postdoctoral training with [[Eric Lander]] at the Whitehead Institute/MIT [[Center for Genome Research]].<ref>[http://mootha.med.harvard.edu/ Mootha Laboratory<!-- Bot generated title -->]</ref> | ||
==References== | ==References== | ||