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'''Vamsi K. Mootha'''  is an [[India|Indian]]-born [[United States|American]] physician-scientist and [[computational biology|computational biologist]]. He is an Investigator of the [[Howard Hughes Medical Institute]], Professor of Systems Biology and Medicine at [[Harvard Medical School]], and is based in the Department of Molecular Biology at [[Massachusetts General Hospital]]. He is also an Institute Member of the [[Broad Institute]].<ref>http://mootha.med.harvard.edu/members_vm.html Mootha's biography</ref>
'''Vamsi K. Mootha'''  is an [[India|Indian]]-born [[United States|American]] physician-scientist and [[computational biology|computational biologist]]. He is an Investigator of the [[Howard Hughes Medical Institute]], Professor of Systems Biology and Medicine at [[Harvard Medical School]], and is based in the Department of Molecular Biology at [[Massachusetts General Hospital]]. He is also an Institute Member of the [[Broad Institute]].<ref>http://mootha.med.harvard.edu/members_vm.html Mootha's biography</ref>


His research group has made major contributions to mitochondrial and systems biology.  His group characterized the mammalian mitochondrial proteome, identified dozens of mitochondrial disease genes, and discovered the molecular identity of the mitochondrial calcium uniporter.  His team has also made the unexpected discovery that in animal models, low oxygen can prevent and alleviate mitochondrial disease.  As a postdoctoral fellow he developed [[Gene Set Enrichment Analysis]], an algorithm that is widely used in genomics and has been implemented into a popular software tool.
His research group has made major contributions to mitochondrial biology and genomics.  His group characterized the mammalian mitochondrial proteome and applied it to identify dozens of mitochondrial disease genes.  His team used integrative genomics to identify the molecular components of the mitochondrial calcium uniporter.  His team has also made the unexpected discovery that in animal models, low oxygen can alleviate mitochondrial disease.  As a postdoctoral fellow he developed [[Gene Set Enrichment Analysis]], an algorithm that is widely used in genomics and has been implemented into a popular software tool.


He is a  2004 recipient of the [[MacArthur Fellows Program|Macarthur Foundation "genius award"]].  He received the 2008 Daland Prize from the [[American Philosophical Society]] and a 2014 [[Padma Shri]] Award from the [[Republic of India]], the fourth highest civilian award given by the Indian government.<ref>[http://www.thehindu.com/news/national/padma-awards-for-7-persons-under-nri-pio-foreign-category/article5618199.ece Padma awards for 7 persons under NRI, PIO, foreign category - The Hindu<!-- Bot generated title -->]</ref><ref>{{Cite web|url=http://www.americanbazaaronline.com/2014/01/27/five-eminent-personalities-us-get-padma-awards-3-indian-americans/|title = Five eminent personalities from the US get Padma awards, 3 of them Indian Americans|date = 27 January 2014}}</ref><ref>[http://www.broad.mit.edu/about/bios/bio-mootha.html Vamsi Mootha | Broad Institute of MIT and Harvard<!-- Bot generated title -->]</ref><ref>[http://jem.rupress.org/cgi/content/full/205/6/1248 Vamsi Mootha: Taking an inventory of mitochondria<!-- Bot generated title -->]</ref>  He was elected to the United States National Academy of Sciences in 2014.  He also served on the Life Sciences jury for the [[Infosys Prize]] in 2017.
He is a  2004 recipient of the [[MacArthur Fellows Program|Macarthur Foundation "genius award"]].  He received the 2008 Daland Prize from the [[American Philosophical Society]] and a 2014 [[Padma Shri]] Award from the [[Republic of India]], the fourth highest civilian award given by the Indian government.<ref>[http://www.thehindu.com/news/national/padma-awards-for-7-persons-under-nri-pio-foreign-category/article5618199.ece Padma awards for 7 persons under NRI, PIO, foreign category - The Hindu<!-- Bot generated title -->]</ref><ref>{{Cite web|url=http://www.americanbazaaronline.com/2014/01/27/five-eminent-personalities-us-get-padma-awards-3-indian-americans/|title = Five eminent personalities from the US get Padma awards, 3 of them Indian Americans|date = 27 January 2014}}</ref><ref>[http://www.broad.mit.edu/about/bios/bio-mootha.html Vamsi Mootha | Broad Institute of MIT and Harvard<!-- Bot generated title -->]</ref><ref>[http://jem.rupress.org/cgi/content/full/205/6/1248 Vamsi Mootha: Taking an inventory of mitochondria<!-- Bot generated title -->]</ref>  He was elected to the United States National Academy of Sciences in 2014 and the National Academy of Medicine in 2021.  He also served on the Life Sciences jury for the [[Infosys Prize]] in 2017.


Mootha graduated from Kelly High School in Beaumont, Texas. Mootha received his [[Bachelor of Science|BS]] in Mathematical and Computational Science from [[Stanford University]] and his M.D. from [[Harvard University]].  He completed his internship and residency in internal medicine at [[Brigham and Women's Hospital]] in Boston, and then pursued postdoctoral training with [[Eric Lander]] at the Whitehead Institute/MIT [[Center for Genome Research]].<ref>[http://mootha.med.harvard.edu/ Mootha Laboratory<!-- Bot generated title -->]</ref>
Mootha graduated from Kelly High School in Beaumont, Texas. He received his [[Bachelor of Science|BS]] in Mathematical and Computational Science from [[Stanford University]] and his M.D. from [[Harvard University]].  He completed his internship and residency in internal medicine at [[Brigham and Women's Hospital]] in Boston, and then pursued postdoctoral training with [[Eric Lander]] at the Whitehead Institute/MIT [[Center for Genome Research]].<ref>[http://mootha.med.harvard.edu/ Mootha Laboratory<!-- Bot generated title -->]</ref>


==References==
==References==

Latest revision as of 21:43, 18 October 2021

Vamsi K. Mootha
Born
Kakinada, Andhra Pradesh, India
CitizenshipUnited States
EducationM.D.
Alma materStanford University
Harvard–MIT Division of Health Sciences and Technology
OccupationProfessor
EmployerHoward Hughes Medical Institute
Massachusetts General Hospital
Harvard Medical School

Vamsi K. Mootha is an Indian-born American physician-scientist and computational biologist. He is an Investigator of the Howard Hughes Medical Institute, Professor of Systems Biology and Medicine at Harvard Medical School, and is based in the Department of Molecular Biology at Massachusetts General Hospital. He is also an Institute Member of the Broad Institute.[1]

His research group has made major contributions to mitochondrial biology and genomics. His group characterized the mammalian mitochondrial proteome and applied it to identify dozens of mitochondrial disease genes. His team used integrative genomics to identify the molecular components of the mitochondrial calcium uniporter. His team has also made the unexpected discovery that in animal models, low oxygen can alleviate mitochondrial disease. As a postdoctoral fellow he developed Gene Set Enrichment Analysis, an algorithm that is widely used in genomics and has been implemented into a popular software tool.

He is a 2004 recipient of the Macarthur Foundation "genius award". He received the 2008 Daland Prize from the American Philosophical Society and a 2014 Padma Shri Award from the Republic of India, the fourth highest civilian award given by the Indian government.[2][3][4][5] He was elected to the United States National Academy of Sciences in 2014 and the National Academy of Medicine in 2021. He also served on the Life Sciences jury for the Infosys Prize in 2017.

Mootha graduated from Kelly High School in Beaumont, Texas. He received his BS in Mathematical and Computational Science from Stanford University and his M.D. from Harvard University. He completed his internship and residency in internal medicine at Brigham and Women's Hospital in Boston, and then pursued postdoctoral training with Eric Lander at the Whitehead Institute/MIT Center for Genome Research.[6]

References[edit]

  1. ↑ http://mootha.med.harvard.edu/members_vm.html Mootha's biography
  2. ↑ Padma awards for 7 persons under NRI, PIO, foreign category - The Hindu
  3. ↑ "Five eminent personalities from the US get Padma awards, 3 of them Indian Americans". 27 January 2014.
  4. ↑ Vamsi Mootha | Broad Institute of MIT and Harvard
  5. ↑ Vamsi Mootha: Taking an inventory of mitochondria
  6. ↑ Mootha Laboratory


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