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	* 2017 [[Knight Bachelor\|knighted]] in the [[2017 New Year Honours]] for services to science and medicine.<ref>{{London Gazette\|issue=61803\|supp=y\|page=N2\|date=31 December 2016}}</ref>		* 2017 [[Knight Bachelor\|knighted]] in the [[2017 New Year Honours]] for services to science and medicine.<ref>{{London Gazette\|issue=61803\|supp=y\|page=N2\|date=31 December 2016}}</ref>
	* 2018 [[Royal Medal]]<ref>[https://royalsociety.org/grants-schemes-awards/awards/royal-medal/ Royal Medal 2018]</ref>		* 2018 [[Royal Medal]]<ref>[https://royalsociety.org/grants-schemes-awards/awards/royal-medal/ Royal Medal 2018]</ref>
			* 2020 [[Millennium Technology Prize]]

	== References ==		== References ==

>SdkbBot: /* Honours and awards */General fixes, removed erroneous space

2021-06-27T14:25:25Z

Honours and awards: General fixes, removed erroneous space

New page

{{Use dmy dates|date=June 2013}}
{{Use Indian English|date=June 2013}}
{{Infobox scientist
| name = Sir Shankar Balasubramanian
| honorific_suffix = {{post-nominals|country=GBR|FRS|FMedSci|size=100%}}
| image = Shankar Balasubramanian, Herchel Smith Professor of Medicinal Chemistry.jpg
| caption = Shankar Balasubramanian, [[Herchel Smith]] Professor of [[Medicinal Chemistry]]
| birth_date = {{Birth date and age|df=yes|1966|09|30}}<ref name="whoswho">
{{Who's Who | author=Anon| surname = Balasubramanian | othernames = Prof. Shankar | id = U256669 | year = 2017 | edition = online [[Oxford University Press]]|location=Oxford|doi=10.1093/ww/9780199540884.013.256669}} {{subscription required}}</ref>
| birth_place = [[Chennai|Madras]], [[Madras State]]<br/> (now [[Chennai]], [[Tamil Nadu]]), India
| alma_mater = [[University of Cambridge]] (MA, MSci, PhD)
| doctoral_advisor = [[Chris Abell]]
| influences = [[Stephen J. Benkovic]]
| doctoral_students = [[Julian Huppert]]<ref name=Huppert2005>{{cite journal|last1=Huppert|first1=J. L.|last2=Balasubramanian|first2=S.|title=Prevalence of quadruplexes in the human genome|journal=[[Nucleic Acids Research]]|volume=33|issue=9|year=2005|pages=2908–2916|doi=10.1093/nar/gki609|pmid=15914667|pmc=1140081}}</ref><ref name=huphd>{{cite thesis|degree=PhD|publisher=University of Cambridge|title=Studies on genomic G-quadruplexes|first= Julian Leon|last=Huppert|date=2005|url=https://idiscover.lib.cam.ac.uk/primo-explore/fulldisplay?docid=44CAM_ALMA21431254530003606&context=L&vid=44CAM_PROD&search_scope=SCOP_CAM_ALL&tab=cam_lib_coll&lang=en_US|id={{EThOS|uk.bl.ethos.604822}}|oclc=885437272|website=lib.cam.ac.uk}}</ref>
| residence = UK
| website = {{URL|http://www.ch.cam.ac.uk/group/shankar}}
https://www.cruk.cam.ac.uk/research-groups/balasubramanian-group
| nationality = {{GBR}}
| thesis_title = Studies on the reaction mechanism of chorismate synthase
| thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386780
| thesis_year = 1992
| awards = {{Plainlist|
* [[Corday-Morgan Prize]] (2002)
* [[EMBO Member]] (2013)<ref name="embo"/>
* [[Tetrahedron Prize]] (2013)
* [[Royal Medal]] (2018)}}
| work_institution = {{Plainlist|
* [[University of Cambridge]]
* [[Pennsylvania State University]]<ref name="whoswho"/>
* [[Cancer Research UK]]
* Cambridge Epigenetix
* [[Solexa]]
* [[Trinity College, Cambridge]]}}|
| known_for = {{Plainlist|
* [[Nucleic acid]]s research
* [[G-quadruplex]]es
* [[DNA Sequencing|Solexa sequencing]] technology}}
}}

'''Sir Shankar Balasubramanian''' {{post-nominals|country=GBR|FRS|FMedSci}} (born 30 September 1966)<ref name="whoswho"/> is an Indian-born British chemist<ref>{{Cite journal
| pmid = 17582897
| year = 2007
| last1 = Balasubramanian
| first1 = S
| title = From DNA to mountain climbing. Shankar Balasubramanian talks to Alison Stoddart about his research and other interests
| journal = Molecular BioSystems
| volume = 3
| issue = 5
| pages = B37
}}</ref><ref>{{Cite journal
| pmid = 23522090
| year = 2013
| last1 = Balasubramanian
| first1 = S
| title = An interview with Shankar Balasubramanian
| journal = Trends in Biochemical Sciences
| volume = 38
| issue = 4
| pages = 170–1
| doi = 10.1016/j.tibs.2013.02.006
}}</ref> and Herchel Smith Professor<ref>{{cite web |title=University of Cambridge, 2011. ''Herchel Smith Academics .'' |url=http://www.herchelsmith.cam.ac.uk/community/academics |url-status=dead |archive-url=https://web.archive.org/web/20121117205122/http://www.herchelsmith.cam.ac.uk/community/academics/ |archive-date=17 November 2012 |df=dmy-all }} [Accessed 8 April 2013].</ref> of Medicinal Chemistry in the [[Department of Chemistry, University of Cambridge|Department of Chemistry]] at the [[University of Cambridge]],<ref name="www-shankar.ch.cam.ac.uk">{{cite web|title=University of Cambridge, 2013. ''The Balasubramanian Group.''|url=http://www-shankar.ch.cam.ac.uk}} [Accessed 4 April 2013].</ref><ref name="ch.cam.ac.uk">University of Cambridge, 2013. ''Professor Shankar Balasubramanian FMedSci FRS.''[online] Available at: <http://www.ch.cam.ac.uk/person/sb10031> [Accessed 8 April 2013].</ref> Senior Group Leader at the [[Cancer Research UK]] Cambridge Institute <ref>Cancer Research UK Cambridge Institute, University of Cambridge, 2012. '' Balasubramanian Group.''[online] Available at: <http://www.cruk.cam.ac.uk/research-groups/balasubramanian-group> [Accessed 4 April 2013].</ref> and Fellow of [[Trinity College, Cambridge]].<ref>Trinity College, Cambridge, 2013. ''The Fellowship.''[online] Available at: <http://www.trin.cam.ac.uk/index.php?pageid=321> [Accessed 4 April 2013].</ref> He is recognised for his contributions in the field of [[nucleic acid]]s.<ref name="scopus">{{Scopus|id=7201550638}}</ref> He is scientific founder of Solexa <ref>Illumina, 2013. ''SBS Technology.''[online] Available at: <{{cite web |url=http://technology.illumina.com/technology/next-generation-sequencing/solexa-technology.html |title=Archived copy |access-date=2014-10-21 |url-status=dead |archive-url=https://archive.is/20141009113509/http://technology.illumina.com/technology/next-generation-sequencing/solexa-technology.html |archive-date=9 October 2014 |df=dmy-all }}> [Accessed 8 April 2013]</ref><ref>{{Cite journal | last1 = Bentley | first1 = D. R. | last2 = Balasubramanian | first2 = S. | last3 = Swerdlow | first3 = H. P. | last4 = Smith | first4 = G. P. | last5 = Milton | first5 = J. | last6 = Brown | first6 = C. G. | last7 = Hall | first7 = K. P. | last8 = Evers | first8 = D. J. | last9 = Barnes | first9 = C. L. | last10 = Bignell | doi = 10.1038/nature07517 | first10 = H. R. | last11 = Boutell | first11 = J. M. | last12 = Bryant | first12 = J. | last13 = Carter | first13 = R. J. | last14 = Keira Cheetham | first14 = R. | last15 = Cox | first15 = A. J. | last16 = Ellis | first16 = D. J. | last17 = Flatbush | first17 = M. R. | last18 = Gormley | first18 = N. A. | last19 = Humphray | first19 = S. J. | last20 = Irving | first20 = L. J. | last21 = Karbelashvili | first21 = M. S. | last22 = Kirk | first22 = S. M. | last23 = Li | first23 = H. | last24 = Liu | first24 = X. | last25 = Maisinger | first25 = K. S. | last26 = Murray | first26 = L. J. | last27 = Obradovic | first27 = B. | last28 = Ost | first28 = T. | last29 = Parkinson | first29 = M. L. | last30 = Pratt | first30 = M. R. | display-authors = 29 | title = Accurate whole human genome sequencing using reversible terminator chemistry | journal = Nature | volume = 456 | issue = 7218 | pages = 53–59 | year = 2008 | pmid = 18987734 | pmc =2581791 | bibcode = 2008Natur.456...53B }}</ref> and Cambridge Epigenetix.<ref>Cambridge Epigenetix, 2013. ''CEGX ''[online] Available at: <http://www.cambridge-epigenetix.com/en_GB/about-us> [Accessed 19 July 2013].</ref><ref name=gov>{{cite web|archive-url=https://web.archive.org/web/20160706081324/https://beta.companieshouse.gov.uk/officers/Ba6y-nMuKv3KG3r7164IhB0Nrs8/appointments|archive-date=2016-07-06|url=https://beta.companieshouse.gov.uk/officers/Ba6y-nMuKv3KG3r7164IhB0Nrs8/appointments|website=companieshouse.gov.uk|publisher=[[Companies House]]|location=London|title=Shankar BALASUBRAMANIAN}}</ref>

==Education==
Born in [[Madras]] (now [[Chennai]]) [[India]] in 1966,<ref name="whoswho"/> Shankar Balasubramanian moved to the UK with his parents in 1967. He grew up in a rural area just outside [[Runcorn]] in [[Cheshire]] and attended Daresbury Primary School, then Appleton Hall High School (which has since amalgamated to form [[Bridgewater High School (Warrington)|Bridgewater High School]]). He then went on to study the [[Natural Sciences Tripos]] at [[Fitzwilliam College, Cambridge]], where he did his undergraduate degree from 1985–88 and continued with a [[Doctor of Philosophy|PhD]]<ref name="shankarphd">{{cite thesis |degree=PhD |first=Shankar|last=Balasubramanian |title=Studies on the reaction mechanism of chorismate synthase |publisher=University of Cambridge |date=1991 |url=http://ulmss-newton.lib.cam.ac.uk/vwebv/holdingsInfo?bibId=5839|oclc=60112382|id={{EThOS|uk.bl.ethos.386780}}|website=lib.cam.ac.uk}}</ref> for research on the [[reaction mechanism]] of the enzyme [[chorismate synthase]] supervised by [[Chris Abell]] (1988-1991).<ref name="fitz">{{cite web|url=http://www.fitz.cam.ac.uk/about/newsitem-3-198|title=Fitz alumni on top science list|year=2014|publisher=Fitzwilliam College|access-date=6 February 2014|url-status=dead|archive-url=https://web.archive.org/web/20140222004916/http://www.fitz.cam.ac.uk/about/newsitem-3-198|archive-date=22 February 2014|df=dmy-all}}</ref>

==Career and research==
Following his PhD, Balasubramanian travelled to the USA as a SERC/NATO Research Fellow and worked in the group of [[Stephen J. Benkovic]] at [[Pennsylvania State University]] (1991-1993). He started his independent academic career in 1994 in the University of Cambridge and has remained there ever since, first as College Lecturer, then University Lecturer (1998), University Reader in Chemical Biology (2003) and Professor of Chemical Biology (2007). He was most recently appointed Herchel Smith Professor of Medicinal Chemistry in 2008.<ref>University of Cambridge, 2013. ''Professor Shankar Balasubramanian The Herchel Smith Professor of Medicinal Chemistry.''[online] Available at: <http://www-shankar.ch.cam.ac.uk/shankar> [Accessed 4 April 2013].</ref> He currently{{when|date=July 2016}} directs research laboratories in the Department of Chemistry<ref name="www-shankar.ch.cam.ac.uk"/><ref name="ch.cam.ac.uk"/> and also the [[Cancer Research UK]] (CRUK) Cambridge Institute at the [[Cambridge Biomedical Campus]].<ref>Cancer Research UK Cambridge Institute, University of Cambridge, 2013. ''Balasubramanian Group.''[online] Available at: <http://www.cruk.cam.ac.uk/research-groups/balasubramanian-group> [Accessed 8 April 2013].</ref> His former doctoral students include [[Julian Huppert]].<ref name=Huppert2005/><ref name=huphd/>

Balasubramanian works in the field of [[nucleic acid]]s. His citation on election to the Royal Society reads: {{centered pull quote|Shankar Balasubramanian is an internationally recognised leader in the field of nucleic acids who is distinguished for pioneering contributions to chemistry and its application to the biological and medical sciences. He is a principal inventor of the leading next generation sequencing methodology, Solexa sequencing, that has made routine, accurate, low-cost sequencing of human genomes a reality and has revolutionised biology. He has made seminal contributions to the identification, elucidation and manipulation of [[Noncoding DNA|non-coding genetic elements]], particularly four-stranded structures called [[G-quadruplex]]es. His work on the intervention of nucleic acid function using small molecules has revealed a number of molecular mechanisms that can be exploited, e.g. to modulate the biology of cancer.<ref>[https://royalsociety.org/people/fellowship/2012/shankar-balasubramanian/]</ref>}}

More recently Balasubramanian has been inventing and applying new chemical methods to study epigenetic changes to DNA bases including single base resolution sequencing of 5-formylcytosine, 5-hydroxymethylcytosine and 5-methylcytosine.<ref>{{Cite journal | doi = 10.1126/science.1220671| title = Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution| journal = Science| volume = 336| issue = 6083| pages = 934–937| year = 2012| last1 = Booth | first1 = M. J.| last2 = Branco | first2 = M. R.| last3 = Ficz | first3 = G.| last4 = Oxley | first4 = D.| last5 = Krueger | first5 = F.| last6 = Reik | first6 = W.| last7 = Balasubramanian | first7 = S.| pmid = 22539555| bibcode = 2012Sci...336..934B| s2cid = 13922525}}</ref><ref>{{Cite journal
| pmid = 22902005
| year = 2012
| last1 = Raiber
| first1 = E. A.
| title = Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase
| journal = Genome Biology
| volume = 13
| issue = 8
| pages = R69
| last2 = Beraldi
| first2 = D
| last3 = Ficz
| first3 = G
| last4 = Burgess
| first4 = H. E.
| last5 = Branco
| first5 = M. R.
| last6 = Murat
| first6 = P
| last7 = Oxley
| first7 = D
| last8 = Booth
| first8 = M. J.
| last9 = Reik
| first9 = W
| last10 = Balasubramanian
| first10 = S
| doi = 10.1186/gb-2012-13-8-r69
| pmc = 3491369
}}</ref><ref>{{Cite journal | doi = 10.1038/nchem.1893| pmid = 24755596| title = Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution| journal = Nature Chemistry| volume = 6| issue = 5| pages = 435–40| year = 2014| last1 = Booth | first1 = M. J. | last2 = Marsico | first2 = G. | last3 = Bachman | first3 = M. | last4 = Beraldi | first4 = D. | last5 = Balasubramanian | first5 = S. | bibcode = 2014NatCh...6..435B| pmc = 4188980}}</ref>

===Honours and awards===
Honours and awards include:
* 1998 [[Glaxo Wellcome]] Award for Innovative Organic Chemistry
* 2002 [[Corday–Morgan Medal]] and Prize of the [[Royal Society of Chemistry]]<ref>Royal Society of Chemistry, 2013. ''Corday-Morgan Medal and Prize Winners''[online] Available at: <http://www.rsc.org/ScienceAndTechnology/Awards/CordayMorganPrizes/PreviousWinners.asp> [Accessed 8 April 2013].</ref>
* 2009 Royal Society [[Mullard Award]]<ref>The Royal Society. ''Royal Society Mullard Award.''[online] Available at: <http://royalsociety.org/awards/mullard-award/> [Accessed 8 April 2013].</ref>
* 2010 [[BBSRC]] Innovator of the Year <ref name="bbsrc.ac.uk">BBSRC, 2013. ''DNA sequencing pioneer named BBSRC Innovator of the Year 2010''[online] Available at: <http://www.bbsrc.ac.uk/news/policy/2010/100319-pr-dna-sequencing-pioneer-innovator.aspx> [Accessed 8 April 2013].</ref>
* 2010 [[BBSRC]] Commercial Innovator of the Year <ref name="bbsrc.ac.uk"/>
* 2011 Elected a [[Fellow of the Academy of Medical Sciences]] (FMedSci)<ref>The Academy of Medical Sciences. ''Directory of Fellows.''[online] Available at: <http://www.acmedsci.ac.uk/p59.html> [Accessed 8 April 2013].</ref>
* 2012 Elected a [[Fellow of the Royal Society]] (FRS) <ref>The Royal Society. ''Fellows.''[online] Available at: <http://royalsociety.org/about-us/fellowship/fellows/> [Accessed 8 April 2013].</ref>
* 2012 Elected a member of the [[European Molecular Biology Organization]] (EMBO) <ref name="embo">EMBO, 2013. ''EMBO welcomes 55 leading life scientists as members''[online] Available at: <http://www.embo.org/news/press-releases/press-releases-2012/embo-welcomes-55-leading-life-scientists-as-members> [Accessed 8 April 2013].</ref>
* 2013 [[Tetrahedron Prize]]<ref>Elsevier Tetrahedron prize winners: <{{cite web |url=http://www.elsevier.com/physical-sciences/chemistry/organic-chemistry/tetrahedron-prize-for-creativity-in-organic-chemistry-or-bioorganic-medicinal-chemistry |title=Archived copy |access-date=2015-01-28 |url-status=dead |archive-url=https://web.archive.org/web/20140909101444/http://www.elsevier.com/physical-sciences/chemistry/organic-chemistry/tetrahedron-prize-for-creativity-in-organic-chemistry-or-bioorganic-medicinal-chemistry |archive-date=9 September 2014 |df=dmy-all }}></ref>
* 2014 [[Biochemical Society]] [[Norman Heatley|Heatley Medal and Prize]]<ref>Biochemical Society, 2009-12.''2014 Biochemical Society award winners announced''[online] Available at: <{{cite web |url=http://www.biochemistry.org/Awards/2014Winners.aspx |title=Archived copy |access-date=2013-04-10 |url-status=dead |archive-url=https://archive.is/20130616235734/http://www.biochemistry.org/Awards/2014Winners.aspx |archive-date=16 June 2013 |df=dmy-all }}> [Accessed 10 April 2013].</ref>
* 2015 [[Chemical Research Society of India]] Medal<ref>https://www.trin.cam.ac.uk/news/honour-for-trinity-fellow-professor-shankar-balasubramanian/</ref>
* 2017 [[Knight Bachelor|knighted]] in the [[2017 New Year Honours]] for services to science and medicine.<ref>{{London Gazette|issue=61803|supp=y|page=N2|date=31 December 2016}}</ref>
* 2018 [[Royal Medal]]<ref>[https://royalsociety.org/grants-schemes-awards/awards/royal-medal/ Royal Medal 2018]</ref>

== References ==
{{Reflist|35em}}

{{FRS 2012}}
{{Authority control}}

{{DEFAULTSORT:Balasubramanian, Shankar}}
[[Category:1966 births]]
[[Category:Living people]]
[[Category:Scientists from Chennai]]
[[Category:Fellows of Trinity College, Cambridge]]
[[Category:Indian emigrants to the United Kingdom]]
[[Category:Members of the European Molecular Biology Organization]]
[[Category:Alumni of Fitzwilliam College, Cambridge]]
[[Category:British biochemists]]
[[Category:Fellows of the Royal Society]]
[[Category:Members of the University of Cambridge Department of Chemistry]]
[[Category:Knights Bachelor]]
[[Category:Tamil biochemists]]

Shankar Balasubramanian - Revision history

Janni: Improved wording and formatting

218.46.22.133 at 09:08, 2 September 2021

>SdkbBot: /* Honours and awards */General fixes, removed erroneous space