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{{short description|Indian cancer researcher}}

{{Infobox person
| name = Satyavati Motiram Sirsat
| image = SatyavatiMSirsat.png
| alt = An older South Asian woman wearing glasses, beads, a sari and a large bindi.
| caption =
| other_names =
| birth_name = Satyavati Motiram
| birth_date = 7 October 1925
| birth_place = Karachi
| death_date = 10 July 2010
| death_place =
| occupation = Cancer researcher
| years_active =
| known_for =
| notable_works =
| spouse(s) =
| relatives =
}}

'''Satyavati Motiram Sirsat''' (7 October 1925 – 10 July 2010) was an Indian cancer researcher.

== Early life ==
Sirsat was born in [[Karachi]], but lived in various cities as a girl.<ref>{{Cite web|last=Singh|first=Avni|date=2019-03-25|title=Satyavati M Sirsat: Pioneer In Indian Cancer Research {{!}} #IndianWomenInHistory|url=https://feminisminindia.com/2019/03/26/satyavati-m-sirsat-cancer-research/|access-date=2020-10-19|website=Feminism In India|language=en-US}}</ref> Her [[Gujarati people|Gujarati]] parents were [[Theosophy|Theosophists]], and she attended [[Kalakshetra Foundation|Kalakshetra]], a theosophy-based school in [[Chennai]], run by [[George Arundale]] and [[Rukmini Devi Arundale|Rukmini Arundale]].<ref name=":0">Sirsat, Satyavati M. [https://www.ias.ac.in/public/Resources/Initiatives/Women_in_Science/Contributors/ssirsat.pdf "Exploring Nature's Secrets"] in Rohini Godbole and Ram Ramaswamy, eds., ''[[Lilavati's Daughters|Lilavati's Daughters: The Women Scientists of India]]'' (Indian Academy of Sciences 2008): 310-313.</ref> She earned a bachelor's degree in [[microbiology]] at [[St. Xavier's College, Mumbai|St. Xavier's College]] in 1947, and completed doctoral studies in [[pathology]] at [[Tata Memorial Centre|Tata Memorial Hospital for Cancer]] in 1958. She pursued further studies in [[Electron microscope|electron microscopy]] in London in 1958.<ref name=":1">{{Cite book|last=Chattopadhyay|first=Anjana|url=https://nbtindia.gov.in/writereaddata/freebooks/pdf/Women%20Scientists%20in%20India.pdf|title=Women Scientists in India: Lives, Struggles & Achievements|date=2018|publisher=National Book Trust, India|isbn=978-81-237-8144-0|language=en}}</ref>

== Career ==
Sirsat began the first electron microscopy laboratory to study cancer in India. She was founder and president of the Electron Microscope Society of India. Her research, which focused on [[oral submucous fibrosis]], was published in ''[[Nature (journal)|Nature]]'',<ref>{{Cite journal|last1=Sirsat|first1=Satyavati M.|last2=Kandarkar|first2=S. V.|date=June 1968|title=Histological changes in the oral mucosa of the wistar rat treated with commercial lime (calcium hydroxide)--an optical and submicroscopic study|url= |journal=British Journal of Cancer|language=en|volume=22|issue=2|pages=303–315|doi=10.1038/bjc.1968.38|pmid=5660135|pmc=2008245|issn=1532-1827}}</ref> ''[[Carcinogenesis (journal)|Carcinogenesis]]'',<ref>{{Cite journal|last1=Kalimi|first1=Ghulam H.|last2=Sirsat|first2=Satyavati M.|date=1984|title=The relevance of gap junctions to stage I tumor promotion in mouse epidermis|url=https://doi.org/10.1093/carcin/5.12.1671|journal=Carcinogenesis|volume=5|issue=12|pages=1671–1677|doi=10.1093/carcin/5.12.1671|pmid=6499119|issn=0143-3334}}</ref> ''Tumori Journal'',<ref>{{Cite journal|last1=Bhisey|first1=Rajani A.|last2=Sirsat|first2=Satyavati M.|date=1986-12-01|title=Ultrastructural Analysis of Epidermal Hyperplasia Induced by Multiple 12-0-Tetradecanoyl-Phorbol-13-Acetate (TPA) Treatment of Mouse Skin|url=https://doi.org/10.1177/030089168607200618|journal=Tumori Journal|language=en|volume=72|issue=6|pages=643–650|doi=10.1177/030089168607200618|pmid=3810868|s2cid=30900735|issn=0300-8916}}</ref> ''[[Journal of Cell Science]],''<ref>{{Cite journal|last1=Rangan|first1=S. R. S.|last2=Sirsat|first2=Satyavati M.|date=1962-03-01|title=The Fine Structure of the Normal Chorio-Allantoic Membrane of the Chick-Embryo|url=https://jcs.biologists.org/content/s3-103/61/17|journal=Journal of Cell Science|language=en|volume=s3-103|issue=61|pages=17–23|issn=0021-9533}}</ref> ''Journal of Investigative Dermatology,''<ref>{{Cite journal|last1=Sirsat|first1=Satyavati M.|last2=Ketkar|first2=M.B.|date=April 1966|title=Influence of Doca on Induced Epidermal Cancers in Mice*|url=https://doi.org/10.1038/jid.1966.53|journal=Journal of Investigative Dermatology|volume=46|issue=4|pages=331–340|doi=10.1038/jid.1966.53|pmid=5936038|issn=0022-202X|doi-access=free}}</ref> and other scholarly journals.<ref>{{Cite journal|last1=Sirsat|first1=Satyavati M.|last2=Pindborg|first2=J. J.|date=1967|title=The Vascular Response in Early and Advanced Oral Submucous Fibrosis|url=https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1699-0463.1967.tb01280.x|journal=Acta Pathologica et Microbiologica Scandinavica|language=en|volume=70|issue=2|pages=179–184|doi=10.1111/j.1699-0463.1967.tb01280.x|pmid=6050371|issn=1600-0463}}</ref> She served on the editorial boards of other journals, including the ''Indian Journal of Experimental Biology Education'', and ''Journal of Biosciences.'' She became a fellow of the [[Indian Academy of Sciences]] in 1975.<ref>{{Cite web|title=Deceased Fellows|url=https://fellows.ias.ac.in/listing/a?fellowship.type=deceased&profile.sex=F|access-date=2020-10-19|website=Indian Academy of Sciences}}</ref>

Sirsat retired from research in 1985, and became a social worker and [[medical ethicist]], and took an interest in [[Ayurveda|ayurvedic]] interventions as cancer treatment.<ref>{{Cite journal|last1=Vaidya|first1=Ashok|last2=Vaidya|first2=Rama|last3=Vaidya|first3=Vidita|last4=Gunvanti|last5=Joshi|first5=Bharati|last6=Mody|first6=Jyoti|last7=Joshi|first7=Jayashree|last8=Amonkar|first8=Ashok|last9=Sirsat|first9=Satyavati|date=2003|title=Spontaneous or Induced Regression of Cancer: A Novel Research Strategy for Ayurvidya|journal=Ancient Science of Life|volume=22|issue=3|pages=75–83|issn=0257-7941|pmc=3331012|pmid=22557089}}</ref> She was active in [[hospice]] work,<ref name=":1" /> and wrote ''Death, the Final Freedom'' (1998) about this work.<ref>{{Cite book|last=Sirsat|first=Satyavati M.|url=https://books.google.com/books?id=jC9MHQAACAAJ|title=Death, the Final Freedom|date=1998|publisher=Gujarat Sahitya Prakash|language=en}}</ref>

Sirsat advised aspiring scientists, "Be honest to your work and true to yourself. Be disciplined. Never disparage the work of your fellow scientists. Be observant — never distort your log or show records to fit a preconceived theory. Above all, life is to learn — so learn, learn and learn!"<ref name=":0" />

== Personal life ==
Satyavati Motiram married fellow cancer researcher M. V. Sirsat.<ref name=":0" /> She died from cancer in 2010, aged 84 years.<ref name=":1" /><ref>{{Cite journal|last=Bhisey|first=Rajani A.|date=2011|title=Satyavati M. Sirsat (1925–2010)|url=https://www.jstor.org/stable/24079137|journal=Current Science|volume=101|issue=7|pages=964–965|jstor=24079137|issn=0011-3891}}</ref>

== References ==
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{{DEFAULTSORT:Sirsat, Satyavati Motiram}}
[[Category:1925 births]]
[[Category:2010 deaths]]
[[Category:Indian women scientists]]
[[Category:Cancer researchers]]
[[Category:Electron microscopy]]
[[Category:People from Karachi]]
[[Category:Gujarati people]]

Satyavati Motiram Sirsat - Revision history

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