2402:3A80:A1E:A3F3:5C2F:FB44:966E:F142: /* Career */

2021-02-27T09:46:58Z

Career

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{{short description|Indian biotechnologist}}
{{BLP primary sources|date=March 2017}}
'''Sampa Das''' is an Indian [[biotechnologist]], [[scientist]], and an expert on public sector [[agricultural biotechnology]].<ref name=":0">{{Cite news|url=http://allianceforscience.cornell.edu/blog/JoanConrow-Sampa-Das-Adapting-Natures-defenses|title=Dr. Sampa Das: Adapting Nature’s defenses|date=2015-07-01|work=Cornell Alliance for Science|access-date=2017-03-04|language=en}}</ref><ref name=":4">{{Cite web|url=http://www.journalistjoanconrow.com/usings-natures-tools/|title=Usings Nature’s Tools {{!}} Journalist Joan Conrow, Original Reportage & Prose|website=www.journalistjoanconrow.com|language=en-US|access-date=2017-03-04}}</ref> She is a fellow of the [[Indian National Science Academy]] (FNA) and the [[National Academy of Sciences]], India (FNASc).<ref name=":1">{{Cite web|url=http://www.boseinst.ernet.in/dpb/SD.htm|title=Prof. Sampa Das - Bose Institute, Kolkata|website=www.boseinst.ernet.in|access-date=2017-03-04}}</ref> Currently, she is Senior Professor and Head of the Division of Plant Biology at [[Bose Institute]] in [[Kolkata]], which is a multi-disciplinary research institution focused on science and technology.<ref name=":0" /><ref name=":4" /><ref name=":1" />

== Education ==
Working under the supervision of Prof S K Sen of Bose Institute, Sampa Das received her doctorate degree in 1981.<ref name=":2">{{Cite book|work=Science and Culture|last1=Das|first1=Sampa|first2=Arun Lahiri |last2=Majumder|publisher=Bose Institute|title=A Journey From Plant Physiology to Plant Biology|year=2012|url=http://www.scienceandculture-isna.org/may_june_12/01%20Editorial.pdf|pages=3}}</ref><ref name=":1" /> Das has worked with national and international individuals studying the mechanisms of plant defence responses against pests and pathogens, with an aim to combat their stress.<ref name=":2" /> She did her post-doctoral training at the [[Friedrich Miescher Institute for Biomedical Research|Friedrich Miescher Institute]] in Switzerland,<ref name=":0" /><ref name=":4" /> where she became interested in plant [[Transformation (genetics)|transformation]], including rice, mustard, and tomatoes.<ref name=":0" /><ref name=":4" />

==Career==
Dr. Das became a faculty member of Bose Institute.<ref name=":2" />

She expanded her research of plant transformation to include [[chickpea]]s and [[mung bean]], two important sources of protein for India's predominantly vegetarian population. Dr. Das began seeking ways to tweak the genetic constitution of these plants to improve their quality and quantity of the produce.<ref name=":0" /><ref name=":4" /> After successfully completing her research on primary levels, she expanded her research to T3 and T4 level plants.<ref name=":0" /><ref name=":4" />

Her research at Bose has included [[Genetic isolation|isolation]], characterization and monitoring the functionality of [[Insecticide|insecticidal]] proteins from plant sources.<ref name=":1" /><ref name=":3">{{Cite web|url=http://boseinst.ernet.in/sampa/|title=Dr. Sampa Das - Bose Institute, Kolkata|website=boseinst.ernet.in|access-date=2017-03-04}}</ref> She has studied [[Gene expression|expression]] of agronomically important genes in crop plants.<ref name=":1" /><ref name=":3" />

She has worked on development of insect resistant [[Genetically modified crops|transgenic]] rice, chickpea and mustard plants free of [[antibiotic resistant]] selection marker through the expression of mannose binding monocot plant lectins and different Bt toxin genes.<ref name=":1" /><ref name=":3" /> She has studied the molecular interaction between receptor proteins identified from target insects and insecticidal lectins as well as different Bt proteins.<ref name=":1" /><ref name=":3" />

Dr. Das has worked on developing understanding of the mechanism of [[Plant defense against herbivory|defense response]] in plants when challenged by various fungal and bacterial pathogens. Isolation and characterization of differentially expressed defense response related genes, proteins from rice and chickpea plants detected at early stage of infection by Fusarium oxysporum f.sp.ciceris and Xanthomonas oryzae pv oryzae, respectively.<ref name=":1" /><ref name=":3" />

She has worked on identification, characterisation and purification of few insecticidal [[lectin]]s and other proteins from plant sources and isolation and cloning of effective insecticidal lectin and other protein coding gene(s) from respective plant genome(s).<ref name=":1" /><ref name=":3" />

Dr. Das has worked on establishment of efficient plant regeneration and transformation protocol for mustard, chickpea and pigeonpea.<ref name=":1" /><ref name=":3" /> Other areas of interest are construction of a number of vectors with different [[T-DNA]] border elements for a better understanding of mechanism of T-DNA integration into host plant and construction of chimeric Bt, protease inhibitor gene (s) and other agronomically important gene(s) constructs for their expression in important crops namely, rice and mustard for increased productivity.<ref name=":3" />

== Awards and honors ==
In 2007, she became a fellow of the Indian National Science Academy and two years later she became a fellow of the National Academy of Sciences India.<ref name=":1" />

== References ==
{{Reflist}}

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{{DEFAULTSORT:Das, Sampa}}
[[Category:Indian biotechnologists]]
[[Category:Bengali chemists]]
[[Category:Fellows of the Indian National Science Academy]]
[[Category:Fellows of The National Academy of Sciences, India]]
[[Category:Women scientists from West Bengal]]
[[Category:Living people]]
[[Category:Indian agriculturalists]]
[[Category:Indian women biologists]]
[[Category:Year of birth missing (living people)]]

Sampa Das - Revision history

2402:3A80:A1E:A3F3:5C2F:FB44:966E:F142: /* Career */