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{{short description|Indian chemist}}
{{cleanup|reason=Unencyclopedic language. Poor structure.|date=March 2019}}
{{Use dmy dates|date=September 2018}}
{{Use Indian English|date=September 2018}}
{{Infobox scientist
| name = Sabyasachi Sarkar
| native_name = সব্যসাচী সরকার
| image = Prof. Sabyasachi Sarkar.jpg
| image_size =
| birth_date = {{Birth date and age text|17 May 1947}}
| birth_place = [[Jamtara]], India
| fields = Bio inorganic chemistry, nano science
| workplaces = [[IIT Kanpur]] [[Indian Institute of Engineering Science and Technology, Shibpur]]
| alma_mater = [[Ramakrishna Mission Vidyamandira]], [[Rajabazar Science College]], [[University of Calcutta]], [[Gorakhpur University]]
| website = {{URL|http://home.iitk.ac.in/~abya}}
}}

'''Sabyasachi Sarkar'''<ref>{{Cite web |url=https://www.researchgate.net/profile/Sabyasachi_Sarkar |title=Sabyasachi Sarkar |website=ResearchGate |access-date=2016-03-25}}</ref> (born 17 May 1947) is an Indian chemist. He has worked with functional models related to [[Hyperthermophile|hyperthermophilic]] to [[Mesophile|mesophilic]] [[metalloprotein]]s enriching [[bioinorganic chemistry]].<ref>{{Cite journal |last1=Sarkar|first1=Sabyasachi|last2=Das|first2=Samar K. |date=August 1992 |title=CO2 fixation by [WIVO(S2C2(CN)2)2]2−: functional model for the tungsten-formate dehydrogenase of ''Clostridium thermoaceticum'' |journal=Proceedings of the Indian Academy of Sciences – Chemical Sciences |doi=10.1007/BF02840500 |volume=104|issue=4|pages=533–534|s2cid=92609296|doi-access=free}}</ref><ref>{{Cite journal |last1=Das |first1=Samar K. |last2=Chaudhury |first2=Pradeep K. |last3=Biswas |first3=Dulali |last4=Sarkar |first4=Sabyasachi |date=2002-05-01 |title=Modeling for the Active Site of Sulfite Oxidase: Synthesis, Characterization, and Reactivity of [MoVIO2(mnt)2]2- (mnt2- = 1,2-Dicyanoethylenedithiolate) |journal=Journal of the American Chemical Society |language=EN |volume=116 |issue=20 |pages=9061–9070 |doi=10.1021/ja00099a024}}</ref><ref>{{Cite journal |last1=Das |first1=Samar K. |last2=Biswas |first2=Dulali |last3=Maiti |first3=Rabindranath |last4=Sarkar |first4=Sabyasachi |date=1996-02-14 |title=Modeling the Tungsten Sites of Inactive and Active Forms of Hyperthermophilic Pyrococcus furiosus Aldehyde Ferredoxin Oxidoreductase |journal=Journal of the American Chemical Society |language=en |volume=118 |issue=6 |pages=1387–1397 |doi=10.1021/ja9511580}}</ref><ref>{{Cite journal |last1=Yadav |first1=Jyoti |last2=Das |first2=Samar K. |last3=Sarkar |first3=Sabyasachi |date=1997-05-07 |title=A Functional Mimic of the New Class of Tungstoenzyme, Acetylene Hydratase |journal=Journal of the American Chemical Society |language=en |volume=119 |issue=18 |pages=4315–4316 |doi=10.1021/ja970134l}}</ref><ref>{{Cite journal |last1=Prasad |first1=Rishitosh |last2=Sarkar |first2=Sabyasachi |date=November 1997 |title=Evolutionary extremophilic Archaeal domain of life |url=http://www.currentscience.ac.in/Downloads/article_id_073_10_0842_0854_0.pdf |journal=Current Science |volume=73 |issue=10 |pages=842–854 |access-date=26 March 2016}}</ref><ref>{{Cite journal |last1=Majumdar |first1=Amit |last2=Pal |first2=Kuntal |last3=Sarkar |first3=Sabyasachi |date=2006-03-11 |title=Chemistry of [Et 4 N] [Mo IV (SPh) (PPh 3) (mnt) 2] as an Analogue of Dissimilatory Nitrate Reductase with Its Inactivation on Substitution of Thiolate by Chloride |journal=Journal of the American Chemical Society |language=en |volume=128 |issue=13 |pages=4196–4197 |doi=10.1021/ja0586135 |pmid=16568972}}</ref> A Replica of a Fishy Enzyme<ref>{{Cite journal |last1=Moula |first1=Golam |last2=Bose |first2=Moumita |last3=Sarkar |first3=Sabyasachi |date=2013-04-17 |title=Replica of a Fishy Enzyme: Structure–Function Analogue of Trimethylamine-N-Oxide Reductase |journal=Inorganic Chemistry |language=EN |volume=52 |issue=9 |pages=5316–5327 |doi=10.1021/ic4002576 |pmid=23594155}}</ref> and the reduced xanthine oxidase<ref>{{Cite journal |last1=Mitra |first1=Joyee |last2=Sarkar |first2=Sabyasachi |title=Modelling the reduced xanthine oxidase in active sulfo and inactive desulfo forms |journal=Dalton Transactions |language=en |volume=42 |issue=9 |pages=3050–3058 |doi=10.1039/c2dt32309e |pmid=23299556 |date=2013-02-05}}</ref> also have been made. Inhibition patterns<ref>{{Cite journal |last1=Chaudhury |first1=P K |last2=Das |first2=S K |last3=Sarkar |first3=S |date=1996-11-01 |title=Inhibition patterns of a model complex mimicking the reductive half-reaction of sulphite oxidase |journal=Biochemical Journal |volume=319 |issue=Pt 3 |pages=953–959 |issn=0264-6021 |pmc=1217881 |pmid=8921005 |doi=10.1042/bj3190953}}</ref> in the Michaelis complex of low molecular weight hepatic sulfite oxidase model complex have been exhibited.<ref>{{Cite journal |last1=Pal |first1=Kuntal |last2=Chaudhury |first2=Pradeep K. |last3=Sarkar |first3=Sabyasachi |date=2007-08-03 |title=Structure of the Michaelis Complex and Function of the Catalytic Center in the Reductive Half-Reaction of Computational and Synthetic Models of Sulfite Oxidase |journal=Chemistry: An Asian Journal |language=en |volume=2 |issue=8 |pages=956–964 |doi=10.1002/asia.200700020 |pmid=17600788 |issn=1861-471X}}</ref> Based on functional mimicking of a series of molybdoenzymes he showed that the even in model enzymatic oxotransfer reactions the participation of similar enzyme-susbrate (E-S) complex is a real entity. Such a chemical spices (E-S) responds to spontaneous intramolecular oxidative addition and reductive elimination to complete the oxotransfer reaction. Such a reaction differs from conventional chemical oxotransfer reaction where the reaction between the starting reactants happens in Eyring activated complex.<ref>{{Cite book |chapter-url=http://pubs.rsc.org/en/content/chapter/bk9781782628774-00068/978-1-78262-877-4#!divabstract |last1=Pakhira |first1=Bholanath |last2=Sarkar |first2=Rudra |last3=Sarkar |first3=Sabyasachi |date=2016-09-29 |pages=68–93 |language=en |doi=10.1039/9781782628828-00068 |chapter=Chapter 3:Electron Transfer Mechanisms in Molybdenum and Tungsten Model Compounds |title=Molybdenum and Tungsten Enzymes |series=Metallobiology |isbn=978-1-78262-877-4}}</ref> He demonstrated that [[carbon dioxide]] molecule does bind to [[magnesium]] in [[chlorophyll]]<ref>{{Cite journal |last1=Bhuyan |first1=Jagannath |last2=Sarkar |first2=Rudra |last3=Sarkar |first3=Sabyasachi |date=2011-11-04 |title=A Magnesium Porphyrin Bicarbonate Complex with CO2-Modulated Photosystem I Action |journal=Angewandte Chemie International Edition |language=en |volume=50 |issue=45 |pages=10603–10607 |doi=10.1002/anie.201103876 |issn=1521-3773 |pmid=21932225}}</ref> in [[photosynthesis]] as proposed by [[Richard Willstätter|R. M. Willstätter]] one-hundred years ago and modeled hydrogenase captioned as better than nature.<ref>{{Cite journal|last1=Begum|first1=Ameerunisha|last2=Moula|first2=Golam|last3=Sarkar|first3=Sabyasachi|date=2010|title=A Nickel(II)–Sulfur-Based Radical-Ligand Complex as a Functional Model of Hydrogenase|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201001812|journal=Chemistry: A European Journal |volume=16|issue=41|pages=12324–12327|doi=10.1002/chem.201001812|pmid=20853299 |issn=1521-3765|url-access=subscription}}</ref> The rare reaction of a Cu(II) complex with aerial oxygen to generate [[superoxide]] anion and Cu(III) has been shown addressing the native [[Superoxide dismutase|SOD]] reaction.<ref>{{Cite journal |last1=Bhattacharya |first1=Dibyendu |last2=Maji |first2=Suman |last3=Pal |first3=Kuntal |last4=Sarkar |first4=Sabyasachi |date=2008-05-01 |title=Formation of Superoxide Anion on Aerial Oxidation of Cu(II)–Porphyrinogen in the Synthesis of Tetrakis(cyclohexyl)porphyrinogenCu(III) Anion |journal=Inorganic Chemistry |language=EN |volume=47 |issue=12 |pages=5036–5038 |doi=10.1021/ic800282j |pmid=18447338}}</ref> Similarly the aspect of copper-molybdenum antagonism in ruminant animals have been investigated.<ref>{{Cite journal |last1=Sarkar |first1=S. |last2=Mishra |first2=S. B. S. |date=1984-09-01 |title=Synthetic aspects of CuMos systems and their possible relevance to copper—molybdenum antagonism |journal=Coordination Chemistry Reviews |volume=59 |pages=239–264 |doi=10.1016/0010-8545(84)85056-0}}</ref> His research has shown the architectural marvel in silk cocoon with the natural thermostatic and humidity control with preferential oxygen gating inside cocoon as green house architecture.<ref>{{Cite journal |last1=Roy |first1=Manas |last2=Meena |first2=Sunil Kumar |last3=Kusurkar |first3=Tejas Sanjeev |last4=Singh |first4=Sushil Kumar |last5=Sethy |first5=Niroj Kumar |last6=Bhargava |first6=Kalpana |last7=Sarkar |first7=Sabyasachi |last8=Das |first8=Mainak |date=2012-12-01 |title=Carbondioxide Gating in Silk Cocoon |journal=Biointerphases |volume=7 |issue=1 |pages=45 |doi=10.1007/s13758-012-0045-7 |pmid=22791361 |s2cid=5742774 |issn=1934-8630|doi-access=free }}</ref> He proposed a new magneto reception mechanism for nocturnal moth in sensing the [[Earth's magnetic field]] to navigate with a stable pool of carbon-centric free radicals along with [[Ferromagnetism|ferromagnetic]] components.<ref>{{Cite journal |last1=Roy |first1=Manas |last2=Kusurkar |first2=Tejas Sanjeev |last3=Maurya |first3=Sandeep Kumar |last4=Meena |first4=Sunil Kumar |last5=Singh |first5=Sushil Kumar |last6=Sethy |first6=Niroj |last7=Bhargava |first7=Kalpana |last8=Sharma |first8=Raj Kishore |last9=Goswami |first9=Debabrata |date=2013-03-24 |title=Graphene oxide from silk cocoon: a novel magnetic fluorophore for multi-photon imaging |journal=3 Biotech |language=en |volume=4 |issue=1 |pages=67–75 |doi=10.1007/s13205-013-0128-2 |pmid=28324464 |issn=2190-572X |pmc=3909567}}</ref> He extended the work on nano carbon<ref>{{Cite journal |last1=Dubey |first1=Prashant |last2=Muthukumaran |first2=Devarajan |last3=Dash |first3=Subhashis |last4=Mukhopadhyay |first4=Rupa |last5=Sarkar |first5=Sabyasachi |date=2005-10-01 |title=Synthesis and characterization of water-soluble carbon nanotubes from mustard soot |journal=Pramana |language=en |volume=65 |issue=4 |pages=681–697 |doi=10.1007/BF03010456 |bibcode=2005Prama..65..681D |s2cid=53490874 |issn=0304-4289}}</ref> and developed cheap sources of water soluble nano carbon including naturally formed graphene oxide from low grade coal.<ref>{{Cite journal |last1=Pakhira |first1=Bholanath |last2=Ghosh |first2=Subrata |last3=Maity |first3=Sheli |last4=Sangeetha |first4=D. N. |last5=Laha |first5=Ankita |last6=Allam |first6=Afreen |last7=Sarkar |first7=Sabyasachi |title=Extraction of preformed graphene oxide from coal: its clenched fist form entrapping large molecules |journal=RSC Adv. |language=en |volume=5 |issue=108 |pages=89076–89082 |doi=10.1039/c5ra15699h |date=2015-10-19|bibcode=2015RSCAd...589076P }}</ref> These are used in the growth of young plants as promoters to slowly release micro nutrients and adsorbed water.<ref>{{Cite journal |last1=Tripathi |first1=Shweta |last2=Sonkar |first2=Sumit Kumar |last3=Sarkar |first3=Sabyasachi |title=Growth stimulation of gram (Cicer arietinum) plant by water soluble carbon nanotubes |journal=Nanoscale |language=en |volume=3 |issue=3 |pages=1176–1181 |doi=10.1039/c0nr00722f |pmid=21253651 |date=2011-03-10|bibcode=2011Nanos...3.1176T }}</ref><ref>{{Cite journal |last1=Sonkar |first1=Sumit Kumar |last2=Roy |first2=Manas |last3=Babar |first3=Dipak Gorakh |last4=Sarkar |first4=Sabyasachi |title=Water soluble carbon nano-onions from wood wool as growth promoters for gram plants |journal=Nanoscale |language=en |volume=4 |issue=24 |pages=7670–7675 |doi=10.1039/c2nr32408c |pmid=23099536 |date=2012-11-26|bibcode=2012Nanos...4.7670S }}</ref><ref>{{Cite journal |last1=Saxena |first1=Manav |last2=Maity |first2=Sheli |last3=Sarkar |first3=Sabyasachi |title=Carbon nanoparticles in 'biochar' boost wheat (Triticum aestivum) plant growth |journal=RSC Adv. |language=en |volume=4 |issue=75 |pages=39948–39954 |doi=10.1039/c4ra06535b |date=September 2014|bibcode=2014RSCAd...439948S }}</ref><ref>{{Cite journal |last1=Tripathi |first1=Shweta |last2=Sarkar |first2=Sabyasachi |date=2014-09-09 |title=Influence of water soluble carbon dots on the growth of wheat plant |journal=Applied Nanoscience |language=en |volume=5 |issue=5 |pages=609–616 |doi=10.1007/s13204-014-0355-9 |s2cid=137168230 |issn=2190-5509|doi-access=free }}</ref> He explored these to explore bio-imaging<ref>{{Cite journal |last1=Ghosh |first1=Mitrajit |last2=Sonkar |first2=Sumit Kumar |last3=Saxena |first3=Manav |last4=Sarkar |first4=Sabyasachi |date=2011-11-18 |title=Carbon Nano-onions for Imaging the Life Cycle of Drosophila Melanogaster |journal=Small |language=en |volume=7 |issue=22 |pages=3170–3177 |doi=10.1002/smll.201101158 |pmid=22012886 |issn=1613-6829}}</ref> and demonstrating that non-toxic carbon nano onion<ref>{{Cite journal |last1=Sonkar |first1=Sumit Kumar |last2=Roy |first2=Manas |last3=Babar |first3=Dipak Gorakh |last4=Sarkar |first4=Sabyasachi |title=Water soluble carbon nano-onions from wood wool as growth promoters for gram plants |journal=Nanoscale |language=en |volume=4 |issue=24 |pages=7670–7675 |doi=10.1039/c2nr32408c |pmid=23099536 |date=2012-11-26|bibcode=2012Nanos...4.7670S }}</ref><ref>{{Cite journal |last1=Sonkar |first1=Sumit Kumar |last2=Ghosh |first2=Mitrajit |last3=Roy |first3=Manas |last4=Begum |first4=Ameerunisha |last5=Sarkar |first5=Sabyasachi |date=2012-06-01 |title=Carbon Nano-Onions as Nontoxic and High-Fluorescence Bioimaging Agent in Food Chain—An In Vivo Study from Unicellular E. coli to Multicellular C. elegans |journal=Materials Express |volume=2 |issue=2 |pages=105–114 |doi=10.1166/mex.2012.1064|s2cid=100916037 }}</ref> can cross [[blood–brain barrier]]<ref>{{Cite journal |last1=Pakhira |first1=Bholanath |last2=Ghosh |first2=Mitrajit |last3=Allam |first3=Afreen |last4=Sarkar |first4=Sabyasachi |title=Carbon nano onions cross the blood brain barrier |journal=RSC Adv. |language=en |volume=6 |issue=35 |pages=29779–29782 |doi=10.1039/c5ra23534k |date=2016-03-21|bibcode=2016RSCAd...629779P |s2cid=101893556 }}</ref> to carry drug as cargo and can be effectively be excreted from the body. The utility of such nano carbon to control [[mosquito]] breeding in preventing mosquito vectors of infectious diseases<ref>{{Cite journal |last1=Saxena |first1=Manav |last2=Sonkar |first2=Sumit Kumar |last3=Sarkar |first3=Sabyasachi |title=Water soluble nanocarbons arrest the growth of mosquitoes |journal=RSC Advances |language=en |volume=3 |issue=44 |pages=22504–22508 |doi=10.1039/c3ra44100h |date=2013-10-21|bibcode=2013RSCAd...322504S }}</ref> and the use of reduced graphene oxide to prevent hospital pathogens have been demonstrated.<ref>{{Cite journal |last1=Dutta |first1=Taposhree |last2=Sarkar |first2=Rudra |last3=Pakhira |first3=Bholanath |last4=Ghosh |first4=Subrata |last5=Sarkar |first5=Ripon |last6=Barui |first6=Ananya |last7=Sarkar |first7=Sabyasachi |title=ROS generation by reduced graphene oxide (rGO) induced by visible light showing antibacterial activity: comparison with graphene oxide (GO) |journal=RSC Adv. |language=en |volume=5 |issue=98 |pages=80192–80195 |doi=10.1039/c5ra14061g |date=2015-09-21|bibcode=2015RSCAd...580192D }}</ref> On the environment aspect the presence of damaged floating carbon nano tubes in [[aerosol]]s is shown to contribute global warming, winter smog and elevating breathing problem.<ref>{{Cite journal |last1=Banerjee |first1=Saumyabrata |last2=Tripathi |first2=Sachchida N. |last3=Das |first3=Utpal |last4=Ranjan |first4=Raju |last5=Jadhav |first5=Nilesh |last6=Singh |first6=Vivek P. |last7=Jariwala |first7=Chinmay |last8=Sonkar |first8=Sumit |last9=Sarkar |first9=Sabyasachi |date=2012-07-15 |title=Enhanced persistence of fog under illumination for carbon nanotube fog condensation nuclei |journal=Journal of Applied Physics |volume=112 |issue=2 |pages=024901–024901–4 |doi=10.1063/1.4736557 |bibcode=2012JAP...112b4901B |issn=0021-8979}}</ref> He demonstrated the adverse effect of soap and detergent discharge near [[tube well]]s in releasing [[Arsenic poisoning|arsenic]] and [[Fluoride toxicity|fluoride contaminated water]].<ref>{{Cite journal |last1=Dey |first1=Soumen |last2=Chatterjee |first2=Shahana |last3=Sarkar |first3=Sabyasachi |date=10 December 2005 |title=Direct and indirect arsenic release from soaps by unhygienic use in tubewells |url=http://repository.ias.ac.in/76907/1/76907.pdf |journal=Current Science }}</ref> He also mapped the degradation of a heritage monument, the [[Taj Mahal]].<ref>{{Cite book |title=Characterization of the dust in the ambience of the Taj Mahal, Agra |last1=Samadhiya |first1=N.K. |last2=Banerjee |first2=Deepankar |last3=Sarkar |first3=Sabyasachi |publisher=Agam Kala Prakashan |year=2009 |editor-last=Jain |editor-first=K.K. |pages=25–30}}</ref>

== Early life and education ==
Prof. Sabysachi Sarkar hails from the family of legal advisor of the local king was born in [[Birbhum district|Birbhum]] (meaning forest land) district, [[West Bengal]] in the Zaminder house of his maternal grandparent. His early education came from [[St. Xavier's College, Kolkata|St. Xavier's College]] and [[Ramakrishna Mission Vidyamandira]], Belurmath. He did a M.Sc. from the prestigious [[Rajabazar Science College]], [[University of Calcutta]] at the age of 19.<ref>{{Cite web |url=https://home.iitk.ac.in/~abya/Reminiscence/reminiscence.html |title=Reminiscence:Santhal Parganas to Chemistry }}</ref> He is the lone living grad student of [[Acharya Prafulla Chandra Ray]] as practicing chemist even today. He started his research under Professor Pulin Behari Sarkar in the [[Rajabazar Science College]]. After learning analytical-inorganic chemistry he learnt thermodynamics from Professor R.P Rastogi of [[Deen Dayal Upadhyay Gorakhpur University|Gorakhpur University]]. He pursued aggregates of metal oxides and sulfides of diverse interest from the school of Professor [[Achim Müller]] in Germany. He practiced research in diversified field of interest including [[Natural environment|environment]], healthcare science, and conservation.

== Professional life ==

=== Fellowships ===
State, National, CSIR, Indian Chemical Society, INSA Research, Academy of Science, Humboldt, DAAD, Raja Ramanna, Royal Society of Chemistry.

=== Honours ===
Professor R.K. Barua Memorial Lecture; Professor R. D. Desai Medal and Prize; Professor Priyadaranjan Ray Memorial Award; Honorary Professor, Faculty of Science –BHU; Annual Professor Sabyasachi Sarkar endowment lecture at RKM Vidyamandira. Belurmath instituted by former PhD student. Honorary Professor Emeritus, IIEST-Shibpur.

=== Literary work ===
He writes satire on Indian science and other science-based articles in Bengali magazines. His full list of writing are available at his [https://home.iitk.ac.in/~abya/literary%20work/literary%20work.html website.]

== References ==
{{Reflist}}

== External links ==
* {{ResearchGate|Sabyasachi_Sarkar}}
* {{LinkedIn page|in/sabyasachi-sarkar-9709b930}}
* {{Google Scholar|zEP-XiEAAAAJ}}

{{authority control}}

{{DEFAULTSORT:Sarkar, Sabyasachi}}
[[Category:1947 births]]
[[Category:Living people]]
[[Category:20th-century Indian chemists]]
[[Category:Fellows of the Royal Society of Chemistry]]
[[Category:Fellows of the Indian National Science Academy]]
[[Category:University of Calcutta alumni]]
[[Category:Academic staff of IIT Kanpur]]

Sabyasachi Sarkar - Revision history

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