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-{{short description|Medical research facility at Karnatak University, Dharwar, Karnataka, India}}
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-According to Pramod B. Gai, professor and coordinator of the Department of Applied Genetics and lead researcher at the centre, studies have revealed the high frequency of consanguineous marriages in South India, especially uncle-niece and first cousin marriages: "Marriages between close relatives are high in rural north Karnataka. This increases the frequency of homozygosity of harmful recessive genes in the population and in turn, increases the co-efficiency of inbreeding. As a result compared to other areas, there is a high frequency of hereditary disorders in the region".
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{{short description|Medical research facility at Karnatak University, Dharwar, Karnataka, India}}
{{Use dmy dates|date=May 2018}}
{{Use Indian English|date=May 2018}}
{{unreferenced|date=December 2008}}
The '''Research Centre for DNA Diagnostics''' (RCDD) is a medical research facility at [[Karnatak University]], [[Dharwar]], [[Karnataka]], [[India]]. The primary objective of the centre is to identify hereditary disorders prevalent in north [[Karnataka]] and to conduct advanced research.

==Research==

According to Pramod B. Gai, professor and coordinator of the Department of Applied Genetics and lead researcher at the centre, studies have revealed the high frequency of consanguineous marriages in South India, especially uncle-niece and first cousin marriages: "Marriages between close relatives are high in rural north Karnataka. This increases the frequency of homozygosity of harmful recessive genes in the population and in turn, increases the co-efficiency of inbreeding. As a result compared to other areas, there is a high frequency of hereditary disorders in the region".

The research conducted at the centre is at four levels — [[single-gene disorder]]s (such as [[Sickle cell anaemia]], [[Thallassemia]], and [[Haemophilia]]), chromosomal disorders (such as [[Down’s Syndrome]], [[Turner syndrome]], [[Klinefelter Syndrome]]), biochemical disorders (such as [[Phenylketonuria]], [[Galactosemia]], [[Alkaptonuria]]) and multifactorial/polygenic disorders (such as [[Diabetes]], [[cardiovascular disease]]s and various types of [[cancer]]).

According to the initial plan, the tests would be conducted on samples taken from patients visiting the [[Karnataka Institute of Medical Sciences]] (KIMS) Hospital, [[Hubli]]. During the next stage, the facility would be extended to other government and private medical colleges in north Karnataka. The facilities would be extended to other parts of the state in phases.

==Counselling centres==

As part of the project, genetic counselling centres would be established at KIMS and RCDD. At a later stage, RCDD also plans to train medical professionals and other doctors in the diagnosis of hereditary diseases and the role of human genetics in medical practice.

{{coord missing|Karnataka}}

{{DEFAULTSORT:Research Center For Dna Diagnostics}}
[[Category:Medical research in India]]
[[Category:Education in Hubli-Dharwad]]
[[Category:Research institutes in Karnataka]]
[[Category:Year of establishment missing]]

Research Center For DNA Diagnostics - Revision history

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