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{{Short description|Indian biochemist and molecular biologist (born 1953)}}
{{Use dmy dates|date=January 2019}}
{{Use Indian English|date=January 2019}}
{{Infobox scientist
| name = Ramakrishnan Nagaraj
| image =
| alt =
| caption =
| birth_date = {{Birth date and age|df=yes|1953|2|10}}
| birth_place = [[Andhra Pradesh]], India
| death_date =
| death_place =
| residence =
| fields = {{ublist | [[Biophysics]] | [[Biochemistry]] }}
| workplaces = {{ublist | [[Centre for Cellular and Molecular Biology]] }}
| alma_mater = {{ublist | [[University of Mumbai]] | [[Indian Institute of Technology, Mumbai]] | [[Indian Institute of Science]] }}
| doctoral_advisor = [[Padmanabhan Balaram]]
| doctoral_students =
| known_for = Design of antibiotic peptides
| awards = 1981 [[Indian National Science Academy|INSA]] Young Scientist Medal<br>1988 [[Indian Academy of Sciences|IAS]] Young Associate Medal<br>1988 [[Council of Scientific and Industrial Research|CSIR]] Young Scientist Award<br>1994 [[Shanti Swarup Bhatnagar Prize]]<br>1995 SBCI P. B. Rama Rao Award
}}

'''Ramakrishnan Nagaraj''' (born 10 February 1953) is an Indian biochemist, molecular biologist and the leader of a team of scientists working in the field of [[peptide]] [[biochemistry]] at [[Centre for Cellular and Molecular Biology]] (CCMB).<ref name="Our People">{{cite web | url=http://www.ccmb.res.in/index.php?view=ourteam&mid=0&id=62&grpid=7 | title=Our People | publisher=Centre for Cellular and Molecular Biology | date=2016 | accessdate=6 October 2016}}</ref> He is known for his studies on [[hemolytic]] and antibacterial properties in synthetic analogs of [[bacterial toxins]].<ref name="Brief Profile of the Awardee">{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=204 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | accessdate=5 October 2016}}</ref> He is a J. C. Bose National fellow of the [[Department of Science and Technology (India)|Department of Science and Technology]] at CCMB and an elected fellow of the [[Indian Academy of Sciences]], [[National Academy of Sciences, India]] and the [[Indian National Science Academy]].<ref name="Indian fellow - Nagaraj">{{cite web | url=http://insaindia.res.in/detail.php?id=N98-1235 | title=Indian fellow - Nagaraj | publisher=Indian National Science Academy | date=2016 | accessdate=6 October 2016 | archive-date=9 October 2016 | archive-url=https://web.archive.org/web/20161009161528/http://insaindia.res.in/detail.php?id=N98-1235 | url-status=dead }}</ref> The [[Council of Scientific and Industrial Research]], the apex agency of the Government of India for scientific research, awarded Nagaraj the [[Shanti Swarup Bhatnagar Prize for Science and Technology]], one of the highest Indian science awards, in 1994, for his contributions to biological sciences.<ref name="View Bhatnagar Awardees">{{cite web | url=http://ssbprize.gov.in/Content/AwardeeList.aspx | title=View Bhatnagar Awardees | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | accessdate=5 October 2016}}</ref>

== Biography ==
Born on 10 February 1953, Ramakrishnan Nagaraj graduated in science from the [[University of Mumbai]] and completed his master's degree at the [[Indian Institute of Technology, Mumbai]] before doing his doctoral research at the [[Indian Institute of Science]] under the guidance of [[Padmanabhan Balaram]], a noted biochemist and [[Padma Bhushan]] laureate.<ref name="Indian fellow - Nagaraj" /> Nagaraj joined the [[Centre for Cellular and Molecular Biology]] (CCMB) in 1980 as a scientist where he heads a team of scientists and pursues his researches on ''structure-function correlations in peptide antibiotics''.<ref name="Scientist Details">{{cite web | url=http://www.ccmb.res.in/index.php?view=scientist&mid=0&id=63&grpid=7 | title=Scientist Details | publisher=Centre for Cellular and Molecular Biology | date=2016 | accessdate=6 October 2016}}</ref> He has done considerable work on [[signal peptides]] and peptide antibiotics and their structure-function relationships.<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | accessdate=5 October 2016 | pages=30}}</ref> Nagaraj is known to have suggested a protocol by which [[hemolytic]] and antibacterial properties of the ''synthetic analogs of [[bacterial toxins]]'' could be separated, an invention which is reported to be of assistance in designing antibiotic peptides. His researches have been documented in several articles; [[PubMed]], an online repository of medical articles, has listed 273 of them.<ref name="Nagaraj on PubMed">{{cite web | url=https://pubmed.ncbi.nlm.nih.gov/?term=Nagaraj%20R%5BAuthor%5D&cauthor=true&cauthor_uid=10590301 | title=Nagaraj on PubMed | publisher=PubMed | date=2016 | accessdate=6 October 2016}}</ref>

== Awards and honors ==
The [[Indian National Science Academy]] awarded Nagaraj the Young Scientists Medal in 1981<ref name="Young Scientist Medal">{{cite web | url=http://insaindia.res.in/youngmedal.php | title=Young Scientist Medal | publisher=Indian National Science Academy | date=2016 | accessdate=6 October 2016 | archive-date=11 May 2021 | archive-url=https://web.archive.org/web/20210511084357/https://www.insaindia.res.in/youngmedal.php | url-status=dead }}</ref> and he held the Young Associateship of the [[Indian Academy of Sciences]] from 1985 to 1988.<ref name="Associate Profile">{{cite web | url=http://www.ias.ac.in/describe/associate/Nagaraj,_Dr._Ramakrishnan | title=Associate Profile | publisher=Indian Academy of Sciences | date=2016 | accessdate=6 October 2016}}</ref> He received the Young Scientist Award of the [[Council of Scientific and Industrial Research]] (CSIR) in 1988; CSIR would honor him again in 1994 with the [[Shanti Swarup Bhatnagar Prize]], one of the highest Indian science awards, in 1994.<ref name="View Bhatnagar Awardees" /> A Homi Bhabha Fellow of 1991,<ref name="Homi Bhabha Fellow">{{cite web | url=http://homibhabhafellowships.com/HomiBhabhaFellow.aspx?id=40 | title=Homi Bhabha Fellow | publisher=Homi Bhabha Fellowships Council | date=2016 | accessdate=6 October 2016}}</ref> Nagaraj is also a recipient of the 1995 P. B. Rama Rao Award of the Society for Biological Chemists, India<ref name="Indian fellow - Nagaraj" /> and an elected fellow of the Indian National Science Academy (1998), Indian Academy of Sciences (1992)<ref name="Fellow profile - Nagaraj">{{cite web | url=http://www.ias.ac.in/describe/fellow/Nagaraj,_Dr_Ramakrishnan | title=Fellow profile - Nagaraj | publisher=Indian Academy of Sciences | date=2016 | accessdate=6 October 2016}}</ref> and the [[National Academy of Sciences, India]].<ref name="NASI fellows">{{cite web | url=http://www.nasi.org.in/fellows.asp?RsFilter=N | title=NASI fellows | publisher=National Academy of Sciences, India | date=2016 | accessdate=6 October 2016 | archive-date=16 July 2015 | archive-url=https://web.archive.org/web/20150716224753/http://www.nasi.org.in/fellows.asp?RsFilter=N | url-status=dead }}</ref>

== Selected bibliography ==
* {{cite journal | title=Interaction of antimicrobial peptides with biological and model membranes: structural and charge requirements for activity |author1=Sitaram, N. |author2=Nagaraj, R. | journal=Biochim Biophys Acta | year=1999 | volume=1462 | issue=2 | pages=29–54 | pmid=10590301 | doi = 10.1016/s0005-2736(99)00199-6| doi-access=free }}
* {{Cite journal|last1=Mandal|first1=M.|last2=Jagannadham|first2=M.V.|last3=Nagaraj|first3=R.|date=March 2002|title=Antibacterial activities and conformations of bovine β-defensin BNBD-12 and analogs:structural and disulfide bridge requirements for activity|journal=Peptides|language=en|volume=23|issue=3|pages=413–418|doi=10.1016/S0196-9781(01)00628-3|pmid=11835989|s2cid=1410192 }}
* {{cite journal | title=Palmitoylated peptides from the cysteine- rich domain of SNAP-23 cause membrane fusion depending on peptide length, position of cysteines, and extent of palmitoylation |author1=Pallavi, B. |author2=Nagaraj, R. | journal= Journal of Biological Chemistry| year=2003 | volume=278 | issue=15 | pages=12737–44 | doi=10.1074/jbc.M208598200 | pmid=12551899|s2cid=400106 | doi-access=free }}
* {{Cite journal|last1=Sowmya|first1=Bekshe L.|last2=Jagannadham|first2=M. V.|last3=Nagaraj|first3=Ramakrishnan|date=2006|title=Interaction of synthetic peptides corresponding to the scaffolding domain of Caveolin-3 with model membranes|journal=Biopolymers|language=en|volume=84|issue=6|pages=615–624|doi=10.1002/bip.20595|pmid=16948121}}
* {{Cite journal|last1=Chaudhary|first1=Nitin|last2=Singh|first2=Shashi|last3=Nagaraj|first3=Ramakrishnan|date=2008|title=Organic solvent mediated self-association of an amyloid forming peptide from β2-microglobulin: An atomic force microscopy study|journal=Biopolymers|language=en|volume=90|issue=6|pages=783–791|doi=10.1002/bip.21087|pmid=18798577|s2cid=34813740 }}

== See also ==
* [[Arthropod defensin]]
* [[Padmanabhan Balaram]]
{{portal|India|Biology}}

== References ==
{{reflist}}

{{SSBPST recipients in Biological Science}}

{{authority control}}

{{DEFAULTSORT:Nagaraj, Ramakrishnan}}
[[Category:Recipients of the Shanti Swarup Bhatnagar Award in Biological Science]]
[[Category:1953 births]]
[[Category:Indian biochemists]]
[[Category:Indian molecular biologists]]
[[Category:Fellows of the Indian Academy of Sciences]]
[[Category:Fellows of the National Academy of Sciences, India]]
[[Category:Fellows of the Indian National Science Academy]]
[[Category:University of Mumbai alumni]]
[[Category:IIT Bombay alumni]]
[[Category:Indian Institute of Science alumni]]
[[Category:Living people]]
[[Category:20th-century Indian biologists]]
[[Category:Scientists from Andhra Pradesh]]
[[Category:Homi Bhabha Fellows]]

Ramakrishnan Nagaraj - Revision history

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