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{{short description|Indian biophysical scientist (born 1953)}}
{{Use dmy dates|date=January 2019}}
{{Use Indian English|date=January 2019}}
{{For|Indian structural biologist|Madhusoodan V. Hosur}}
{{Infobox person
| name = Ramakrishna V. Hosur
| image = Professor R.V.Hosur receiving a Padma Shri Award.jpg
| caption=Professor Hosur receiving the Padma Shri Award from [[President of India]] [[Pranab Mukherjee]] in 2014
| imagesize =
| birth_date = {{Birth date and age|df=yes|1953|05|16}}
| birth_place = India
| death_date =
| death_place =
| restingplace =
| restingplacecoordinates =
| othername =
| occupation = Biophysical scientist
| yearsactive =
| spouse = Medhavini Hosur
| domesticpartner =
| children = Pavan Hosur(son) Kirti Hosur Rai(daughter)
| parents =
| website =
| awards = [[Padma Shri]] 
Bruker Young Scientist Award INSA Young Scientist Medal B. M. Birla Award Society for Cancer Research Award J. C. Bose National Fellowship Prof. G. N. Ramachandran Gold Medal Acharya Prafulla Chandra Ray Memorial Award Fellow of International Society of Magnetic Resonance
}}

'''Professor Ramakrishna Vijayacharya Hosur''' is an Indian biophysical scientist, known for his expertise in the areas of [[nuclear magnetic resonance]] and [[molecular biophysics]].<ref name="INSA">{{cite web | url=http://insaindia.org/detail.php?id=N95-1175 | title=INSA | publisher=INSA | date=2014 | access-date=30 October 2014}}</ref><ref name="TIFR" /> The [[Government of India]] honoured him, in 2014, by awarding him the [[Padma Shri]], the fourth highest civilian award, for his contributions to the fields of science and technology.<ref name="Padma 2014">{{cite web | url=http://www.pib.nic.in/newsite/PrintRelease.aspx?relid=102735 | title=Padma 2014 | publisher=Press Information Bureau, Government of India | date=25 January 2014 | access-date=28 October 2014}}</ref>

==Biography==
[[File:HWB-NMR - 900MHz - 21.2 Tesla.jpg|240px|right|thumb|A 900MHz NMR instrument with a 21.1 T magnet]]
Ramakrishna Vijayacharya Hosur was born in the South Indian state of Karnataka on 16 May 1953.<ref name="INSA" /><ref name="TIFR CV">{{cite web | url=http://www.tifr.res.in/~hosur/ | title=TIFR CV | publisher=TIFR | date=2014 | access-date=30 October 2014}}</ref> He graduated with chemistry, Physics and Maths as optional subjects in 1971 securing the 5th rank from [[Karnatak University]]<ref name="INSA" /> and did his masters in Chemistry, MSc, from the [[Indian Institute of Technology, Mumbai]] (IIT-B) with third rank, in 1973. This was followed by a PhD from the [[Tata Institute of Fundamental Research]] (TIFR), Mumbai in 1978.<ref name="INSA" /><ref name="TIFR">{{cite web | url=http://www.tifr.res.in/~dcs/index.php?option=com_content&view=article&id=14&Itemid=121 | title=TIFR | publisher=TIFR | date=2014 | access-date=30 October 2014}}</ref><ref name="TIFR CV" />

Hosur started his career by joining TIFR as a Research Associate in August 1978<ref name="INSA" /> and was promoted as a TIFR Fellow in 1980, a status he maintained till 1986. In between, in 1981, he took a long leave of two years from the institute and did post doctoral research at the [[ETH Zurich]]<ref name="INSA" /><ref name="TIFR" /> where he worked in the company of [[Richard R. Ernst|Professor Richard R. Ernst]] and [[Kurt Wuthrich|Professor Kurt Wuthrich]], who would eventually win [[Nobel Prize]] in 1991 and 2002 respectively.<ref name="TIFR CV" /> In 1986, Hosur rejoined TIFR in the post of the [[Reader (academic rank)|Reader]]. Five years later, he was promoted as the Associate Professor and then as the Professor in 1996. Hosur is the Senior Professor at the Tata Institute since 2003 in the Department of Chemical Sciences.<ref name="INSA" /><ref name="TIFR CV" /> Professor Hosur has also worked at the Columbia University, New York, at Professor D. J. Patel's laboratory for three months (20 August - 20 November) in 1988.<ref name="TIFR CV" /> During his TIFR career, Hosur is reported to have been active in the administration of the institute by holding the chair of the Department of Chemical Sciences, Advisory Committee for Administration and Finance, and the Standing Committee on Administration for various tenures. He was also the Vigilance Officer of the institute from 2002 till 2004 and is the Convener for the National Facility for High Field Nuclear Magnetic Resonance since 2002 till date.<ref name="TIFR CV" />

Ramakrishna Hosur is married and has two children and the family lives in Mumbai.<ref name="TIFR CV" />

==Legacy==
Hosur has taught at the [[Tata Institute of Fundamental Research]], [[Indian Institute of Technology Mumbai]] and National Institute of Technology Rourkela on [[nuclear magnetic resonance]] and is credited with pioneering research on biomolecular nuclear magnetic resonance, molecular biophysics, and biophysical chemistry at these institutions.<ref name="INSA" /><ref name="TIFR contribs" /> The efforts of Dr. Hosur has led to the discovery of new structural motifs in quadruplex DNA structures; A-tetrad, T-tetrad and C-tetrad<ref name="TIFR contribs">{{cite web | url=http://www.tifr.res.in/~hosur/ | title=TIFR contribs | publisher=TIFR | date=2014 | access-date=30 October 2014}}</ref> and the development of new multidimensional NMR pulse sequences.<ref name="INSA" /> He is reported to have explained the folding hierarchy in HIV-1 protease, <blockquote>''the native state energy landscape, and structural and dynamic characteristics of SUMO-1 protein along the equilibrium folding pathways''</blockquote> and also shown experimentally that the progress of the native contacts is not monotonous.<ref name="INSA" />

Hosur is reported to have developed a new NMR based theoretical model which is said to be of assistance in the structural studies on proteases. He has also developed ''scaling techniques''<ref name="TIFR contribs" /> for the enhancement of resolution and sensitivity and proposed what [[Indian Academy of Sciences]] quotes as:<ref name="INSA" /><ref name="TIFR contribs" /><blockquote>''a pH switch mechanism for cargo trafficking by DLC8 protein inside living cells''.
</blockquote>

Hosur has delivered keynote addresses at various international conferences and has lectured at many international institutions.<ref name="TIFR CV" /> He has also taken part in organizing many international conferences.<ref name="TIFR CV" /> He has also guided many students in their doctoral research.<ref name="INSA" /><ref name="TIFR CV" />

Hosur is credited with 3 books<ref name="Abe Books">{{cite web | url=https://www.abebooks.com/book-search/author/g-govil-r-v-hosur/ | title=Abe Books | publisher=Abe Books | date=2014 | access-date=30 October 2014}}</ref> of which two as editor, three book reviews, three technical reports and over 150 articles,<ref name="Bologna University">{{cite web | url=http://serials.unibo.it/cgi-ser/start/en/spogli/ds-s.tcl?authors=%22+Hosur%2C+RV%22&language=ENGLISH | title=Articles on Bologna University Catalogue | publisher=Bologna University | date=2014 | access-date=30 October 2014}}</ref><ref name="Research Index">{{cite web | url=http://researchindex.net/author/Hosur,_R.V./536fe66d26184448c50c4e66 | title=List of Articles on Research Index | publisher=Research Index | date=2014 | access-date=30 October 2014}}</ref> published in national and international peer reviewed journals.<ref name="TIFR CV" /><ref name="Bologna University"/><ref name="Research Index"/> The [[US National Library of Medicine]] has listed 112 articles by Dr. Hosur in their online repository.<ref name="US National Library of Medicine">{{cite web | url=https://pubmed.ncbi.nlm.nih.gov/?term=Hosur%20RV%5BAuthor%5D&cauthor=true&cauthor_uid=20236846 | title=List of Articles on US National Library of Medicine repository | publisher=US National Library of Medicine | date=2014 | access-date=30 October 2014}}</ref>
* BEST-HNN and 2D (HN)NH experiments for rapid backbone assignment in proteins<ref name="BEST-HNN and 2D (HN)NH experiments for rapid backbone assignment in proteins">{{cite journal | title=BEST-HNN and 2D (HN)NH experiments for rapid backbone assignment in proteins | vauthors=Kumar D, Paul S, Hosur RV | journal=J Magn Reson |date=November 2010 | volume=204 | issue=1 | pages=111–7 | doi=10.1016/j.jmr.2010.02.013 | pmid=20236846| bibcode=2010JMagR.204..111K }}</ref>
* NMR insights into the core of GED assembly by H/D exchange coupled with DMSO dissociation and analysis of the denatured state<ref name="NMR insights into the core of GED assembly by H/D exchange coupled with DMSO dissociation and analysis of the denatured state">{{cite journal | title=NMR insights into the core of GED assembly by H/D exchange coupled with DMSO dissociation and analysis of the denatured state | vauthors=Chakraborty S, Hosur RV | journal=J Mol Biol |date=February 2011 | volume=405 | issue=5 | pages=1202–14 | doi=10.1016/j.jmb.2010.11.050 | pmid=21144852}}</ref>
* Visualization of early events in acetic acid denaturation of HIV-1 protease: A molecular dynamics study<ref name="Visualization of early events in acetic acid denaturation of HIV-1 protease: A molecular dynamics study">{{cite journal | title=Visualization of early events in acetic acid denaturation of HIV-1 protease: A molecular dynamics study | vauthors=Borkar AN, Rout MK, Hosur RV | journal=PLOS ONE |date=June 2011 | volume=6 | issue=6 | doi=10.1371/journal.pone.0019830 | pmid=21738569 | article-number=e19830 | pmc=3126794| bibcode=2011PLoSO...619830B | doi-access=free }}</ref>
* AUTOBA: Automation of Backbone Assignment from HN(C)N Suite of Experiments<ref name="AUTOBA: Automation of Backbone Assignment from HN(C)N Suite of Experiments">{{cite journal | title=AUTOBA: Automation of Backbone Assignment from HN(C)N Suite of Experiments | vauthors=Borkar A, Kumar D, Hosur RV | journal=J Biomol NMR |date=July 2011 | volume=50 | issue=3 | pages=285–97 | doi=10.1007/s10858-011-9518-0 | pmid=21626212| s2cid=42262998 }}</ref>
* NMR derived Model of GED self association: relevance to dynamin assembly<ref name="NMR derived Model of GED self association: relevance to dynamin assembly">{{cite journal | title=NMR derived Model of GED self association: relevance to dynamin assembly |author1=Swagata Chakraborty |author2=Supriya Pratihar |author3=Ramakrishna V. Hosur | journal=PLOS ONE |date=January 2012 | doi=10.1371/journal.pone.0030109 | volume=7 |issue = 1| article-number=e30109 | pmid=22253896 | pmc=3257262|doi-access=free }}</ref>

==Positions==
Hosur is life member of Indian Biophysical Society, [[Indian Science Congress Association]], Society for Biological Chemists, India and the [[Chemical Research Society of India]].<ref name="TIFR CV" /> He is a member of the International Society of Magnetic Resonance,<ref name="INSA" /> the Society for Cancer Research and Communication, Mumbai and [[American Chemical Society]].<ref name="TIFR CV" /> He has led, in the capacity of the President, such organizations as Indian Biophysical Society,<ref name="INSA" /> New Biology Section of the [[Indian Science Congress]],<ref name="INSA" /> and the National Magnetic Resonance Society.<ref name="TIFR CV" /> He has also served as the council member of Chemical Research Society of India, ICMRBS, Centre for Biomedical Magnetic Resonance,<ref name="INSA" /> Research Council of IICB,<ref name="INSA" /> Kolkata, INSA,<ref name="INSA" /> NASI, and ISCA.<ref name="TIFR CV" />

Hosur, founder and life member of the National Magnetic Resonance Society,<ref name="TIFR CV" /> is a reviewer for international journals such as [[International Journal of Quantum Chemistry]], [[Journal of Biomolecular NMR]] and Biochemistry USA and a reviewer for proposals of grant of international funding agencies viz. [[Wellcome Trust]], UK, [[Erwin Schrodinger]] Fellowship, Indo Swiss and Indo French collaborative projects and Austrian Science Foundation.<ref name="TIFR CV" /> He is also an examiner for the award of PhD at the Indian Institutes of Technology, Bangalore, Mumbai and Delhi.<ref name="TIFR CV" />

Prof. Hosur has been appointed as a distinguished visiting professor in the Department of Biosciences and Bioengineering in IIT Bombay from 4 September 2018.

==Awards and recognitions==
Hosur has been honored by many scientific and academic institutions by way of fellowships and associateships. He was a Young Associate of the Indian Academy of Sciences during 1985-88. He is Fellow of the [[Indian Academy of Sciences]] (FASc),<ref name="INSA" /> [[Indian National Science Academy]] (FNA), [[National Academy of Sciences]] (FNASc)<ref name="INSA" /> and [[The Academy of Sciences for the Developing World]] (TWAS).<ref name="TIFR CV" /> He has also been awarded Oration awards such as B. D. Tilak Lecture Award of [[Bombay University]] in 1989,<ref name="INSA" /> R. K. Asundi Lecture Award of [[Indian National Science Academy]] in 1998,<ref name="INSA" /> Dr. Jagdish Shankar Lecture Award of [[Indian National Science Academy]] in 2003,<ref name="INSA" /> IICB Foundation Day lecture Award of [[Indian Institute of Chemical Biology]], Kolkata in 2004, RRL Foundation Day lecture of [[Regional Research Laboratory]], Trivandrum in 2006 and Fr. Yeddanapalli Memorial lecture of [[Indian Chemical Society]] in 2009.<ref name="TIFR CV" />

Known as an efficient lecturer and honored by the ''Honorary Mention'' at the International Summer School on Quantum Chemistry held at [[Uppsala]], Sweden during August–September, 1975,<ref name="TIFR CV" /> Dr. Hosur is a recipient of several awards such as:
* Young Scientist Award - [[Bruker Corporation]] - 1983<ref name="INSA" /><ref name="TIFR CV" />
* Young Scientist Medal - [[Indian National Science Academy]] - 1984<ref name="INSA" /><ref name="TIFR CV" />
* B. M. Birla Award - Birla Science Centre - 1992<ref name="INSA" /><ref name="TIFR CV" />
* 3rd Annual Award - Society for Cancer Research - 1998<ref name="INSA" /><ref name="TIFR CV" />
* J. C Bose National Fellowship - [[Department of Science and Technology (India)|Department of Science and Technology]], Government of India - 2007<ref name="INSA" /><ref name="TIFR CV" />
* Prof. G. N. Ramachandran Gold Medal - [[Council for Scientific and Industrial Research]] - 2009<ref name="TIFR CV" />
* Acharya Prafulla Chandra Ray Memorial Award - [[Indian Chemical Society]] - 2011<ref name="TIFR CV" />
* Fellow of International Society of Magnetic Resonance (ISMAR) (2013)<ref>{{cite web|title= Fellow of ISMAR|url=http://www.weizmann.ac.il/ISMAR/ismar-organization#constitution}}</ref>

The [[Government of India]] honored Ramakrishna Hosur with the [[Padma Shri]] by including him in the 2014 [[Republic Day of India|Republic Day]] Honours.

==See also==
{{Div col|colwidth=30em}}
* [[Nuclear magnetic resonance spectroscopy]]
* [[Tata Institute of Fundamental Research]]
{{div col end}}
{{portal|India}}

==References==
{{Reflist}}

==Further reading==
* {{cite journal | title=BEST-HNN and 2D (HN)NH experiments for rapid backbone assignment in proteins | vauthors=Kumar D, Paul S, Hosur RV | journal=J Magn Reson |date=November 2010 | volume=204 | issue=1 | pages=111–7 | doi=10.1016/j.jmr.2010.02.013 | pmid=20236846| bibcode=2010JMagR.204..111K }}
* {{cite journal | title=NMR insights into the core of GED assembly by H/D exchange coupled with DMSO dissociation and analysis of the denatured state | vauthors=Chakraborty S, Hosur RV | journal=J Mol Biol |date=February 2011 | volume=405 | issue=5 | pages=1202–14 | doi=10.1016/j.jmb.2010.11.050 | pmid=21144852}}
* {{cite journal | title=Visualization of early events in acetic acid denaturation of HIV-1 protease: A molecular dynamics study | vauthors=Borkar AN, Rout MK, Hosur RV | journal=PLOS ONE |date=June 2011 | volume=6 | issue=6 | doi=10.1371/journal.pone.0019830 | pmid=21738569 | article-number=e19830 | pmc=3126794| bibcode=2011PLoSO...619830B | doi-access=free }}
* {{cite journal | title=AUTOBA: Automation of Backbone Assignment from HN(C)N Suite of Experiments | vauthors=Borkar A, Kumar D, Hosur RV | journal=J Biomol NMR |date=July 2011 | volume=50 | issue=3 | pages=285–97 | doi=10.1007/s10858-011-9518-0 | pmid=21626212| s2cid=42262998 }}
* {{cite journal | title=NMR derived Model of GED self association: relevance to dynamin assembly |author1=Swagata Chakraborty |author2=Supriya Pratihar |author3=Ramakrishna V. Hosur | journal=PLOS ONE |date=January 2012 | doi=10.1371/journal.pone.0030109 | volume=7 |issue = 1| article-number=e30109 | pmid=22253896 | pmc=3257262|doi-access=free }}

==External links==
* {{cite web | url=https://pubmed.ncbi.nlm.nih.gov/?term=Hosur%20RV%5BAuthor%5D&cauthor=true&cauthor_uid=20236846 | title=List of Articles on US National Library of Medicine repository | publisher=US National Library of Medicine | date=2014 | access-date=30 October 2014}}
* {{cite web | url=http://serials.unibo.it/cgi-ser/start/en/spogli/ds-s.tcl?authors=%22+Hosur%2C+RV%22&language=ENGLISH | title=Articles on Bologna University Catalogue | publisher=Bologna University | date=2014 | access-date=30 October 2014}}
* {{cite web | url=http://researchindex.net/author/Hosur,_R.V./536fe66d26184448c50c4e66 | title=List of Articles on Research Index | publisher=Research Index | date=2014 | access-date=30 October 2014}}

{{2000s Padma Shri Award Recipients in Science & Engineering}}
{{Authority control}}

{{DEFAULTSORT:Hosur, Ramakrishna V.}}
[[Category:1953 births]]
[[Category:Living people]]
[[Category:Recipients of the Padma Shri in science & engineering]]
[[Category:Scientists from Karnataka]]
[[Category:University of Mumbai alumni]]
[[Category:Karnatak University alumni]]
[[Category:Indian biophysicists]]
[[Category:20th-century Indian biologists]]
[[Category:20th-century Indian physicists]]
[[Category:IIT Bombay alumni]]

Ramakrishna V. Hosur - Revision history

Ayurtreatservices: adding a pg - done