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{{Short description|Public health research organization}}
{{Multiple issues|{{primary sources|date=June 2023}}
{{tone|date=June 2023}}}}
{{infobox organization
| image = OHT Mnemonic.png
| abbreviation =
| formation = {{Start date|2009}}
| headquarters = 5636 Connecticut Avenue NW,
PO Box 42735, Washington, D.C.
20015, U.S.A.
| location = [[Washington, D.C.]]
| leader_title = Founder & President
| leader_name = [[Ramanan Laxminarayan]]
| website = {{URL|onehealthtrust.org}}
}}

'''One Health Trust''', formerly the '''Center for Disease Dynamics, Economics & Policy''', is a public health [[Research institute|research organization]] with offices in [[Washington, D.C.]], and [[Bangalore|Bangalore, India]].<ref>{{cite web |title=About Us |url=https://www.ucis.pitt.edu/global/one-health-trust |access-date=19 September 2024 |website=University of Pittsburgh Center for International Studies}}</ref>

Established in 2010, the organization announced its transition to becoming the One Health Trust in 2022<ref>{{cite web |title=CDDEP is becoming the One Health Trust |url=https://securesustain.org/abstract/one-health-trust/ |access-date=19 September 2024 |website=The Security & Sustainability Guide}}</ref> to reflect an expanded research focus. This shift broadened the organization's scope of to include One Health topics, such as [[Veterinary medicine|animal health]], [[planetary health]], and [[climate change]].<ref>{{Cite web |title=One Health |url=https://www.who.int/news-room/questions-and-answers/item/one-health |access-date=2023-11-28 |website=www.who.int |language=en}}</ref>

==Overview==
The One Health Trust has a multidisciplinary team comprising [[Economist|economists]], [[epidemiologists]], [[social scientists]], [[Microbiologist|microbiologists]], [[Veterinarian|veterinarians]], [[medical doctors]], and disease modelers. The One Health Trust research areas include [[antimicrobial resistance]], [[Zoonosis|zoonotic]] and [[Vector-borne diseases|vector borne diseases]], [[environmental health]], social determinants of health, [[Vaccine|vaccines]] and [[immunization]], and other topics related to the One Health approach.<ref>{{cite web |title=Research Areas |url=https://www.thelancet.com/series/antibiotic-resistance |access-date=19 September 2024 |website=The Lancet}}</ref>

==Primary activities==

=== WHO Collaborating Center for Antimicrobial Resistance ===
The One Health Trust has been a [[World Health Organization collaborating centre|World Health Organization Collaborating Center]] for [[antimicrobial resistance]] since 2020. The One Health Trust's researchers support the [[WHO]] in writing country-specific policy and information briefs reviewing progress in implementing national action plans on antimicrobial resistance as a World Health Organization Collaborating Center.<ref>{{cite web |title=World Health Organization GLASS WHO AMR CC Network |url=https://www.who.int/initiatives/glass/network |website=World Health Organization}}</ref><ref>{{cite web |title=WHO Collaborating Centres |url=https://apps.who.int/whocc/Detail.aspx?zAdJQxqXdqM+yVTBgU9HwA== |website=World Health Organization}}</ref><ref>{{cite web |title=WHO- Mali National Action Plan on AMR |url=https://www.who.int/publications/i/item/9789240065468 |website=World Health Organization |access-date=17 February 2023}}</ref>

=== Antimicrobial Resistance Research in Africa ===
As part of the Mapping Antimicrobial Resistance and Antimicrobial Use Partnership consortium,<ref>{{cite web |title=MAAP-African Society for Laboratory Medicine |url=https://aslm.org/what-we-do/maap/ |website=African Society for Laboratory Medicine}}</ref> One Health Trust conducted [[Dataveillance|data surveillance]] and analysis in [[Africa]] to determine the extent of antimicrobial resistance in the continent. The consortium included the African Society for Laboratory Medicine, [[Africa Centres for Disease Control and Prevention|Africa Centers for Disease Control and Prevention]],<ref>{{cite web |title=Africa Centres for Disease Control and Prevention |url=https://en.wikipedia.org/wiki/Africa_Centres_for_Disease_Control_and_Prevention |website=Wikipedia- Africa Centres for Disease Control and Prevention}}</ref>{{Circular reference|date=May 2024}} West African Health Organization, East Central & Southern Africa Health Community, [[IQVIA]],{{clarify|What is IQVIA?|date=November 2023}} and Innovative Support to Emergencies, Diseases and Disasters.

The project was funded by the Fleming Fund<ref>{{cite web |url=https://www.flemingfund.org/publications/announcing-the-mapping-antimicrobial-resistance-and-antimicrobial-use-partnership-maap-project/ |website=Fleming Fund |title=Announcing the Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) project |access-date=4 April 2019}}</ref> and involved data collection on antimicrobial resistance from public and private laboratories and [[Pharmacy|pharmacies]] throughout Africa. The Mapping Antimicrobial Resistance and Antimicrobial Use Partnership consortium reviewed 819,584 antimicrobial resistance records from 2016-2019 from 205 laboratories across the 14 [[African Union member states|African Union Member States]] — [[Burkina Faso]], [[Cameroon]], [[Eswatini]], [[Gabon]], [[Ghana]], [[Kenya]], [[Malawi]], [[Nigeria]], [[Senegal]], [[Sierra Leone]], [[Tanzania]], [[Uganda]], [[Zambia]], and [[Zimbabwe]].<ref>{{cite web |title=Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) Country Reports |url=https://africacdc.org/download/mapping-antimicrobial-resistance-and-antimicrobial-use-partnership-maap-country-reports/ |website=Africa CDC |access-date=20 July 2023}}</ref>

=== The OxygenForIndia Initiative ===
The OxygenForIndia initiative was launched by One Health Trust and partnering institutions to address critical [[medical oxygen]] shortages in India.<ref>{{cite web |title=India’s Crisis Marks a New Phase in the Pandemic |url=https://www.newyorker.com/science/medical-dispatch/indias-crisis-marks-a-new-phase-in-the-pandemic |website=The New Yorker |access-date=13 May 2021}}</ref>

In April 2021, during a medical oxygen supply crisis,<ref>{{cite web |title=Critical oxygen shortage underlines severity of India’s Covid crisis |url=https://www.ft.com/content/9b892baa-5b2a-41a6-8a71-9a46d9ac9262 |website=Financial Times}}</ref><ref>{{cite web |title=Explained: Why India is facing oxygen shortage during 2nd Covid wave |url=https://www.indiatoday.in/coronavirus-outbreak/story/explained-why-india-is-facing-oxygen-shortage-during-2nd-covid-wave-1793435-2021-04-21 |website=India Today |access-date=22 April 2021}}</ref> OxygenForIndia deployed 20,000 reusable oxygen cylinders and 3,000 [[Oxygen concentrator|oxygen concentrators]] in 57 urban and rural centers across India. Currently, OxygenForIndia is working to build a stable and reliable oxygen supply system<ref>{{cite web |title=Healthcube enabling distribution of medical oxygen across India through OxygenForIndia initiative by CDDEP |url=https://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/healthcube-enabling-distribution-of-medical-oxygen-across-india-through-oxygenforindia-initiative-by-cddep/articleshow/82431851.cms |website=The Economic Times |access-date=6 May 2021}}</ref> to avoid preventable deaths and improve [[pandemic]] preparedness. Researchers are evaluating fiscal initiatives and building India's health system capacities.<ref>{{cite web |title=No shortage in future: India unveils blueprint for a national medical oxygen grid |url=https://thesouthfirst.com/health/no-shortage-in-future-india-unveils-blueprint-for-a-national-medical-oxygen-grid/ |website=South First |access-date=19 October 2022}}</ref>

=== Global Antibiotic Resistance Partnership ===
With funding from the [https://www.gatesfoundation.org/ Gates Foundation], the One Health Trust is a technical partner in the [https://www.amr-insights.eu/global-antibiotic-resistance-partnership-garp/ Global Antibiotic Resistance Partnership], which was initiated in 2008 to help low- and middle-income countries develop country-led strategies and policies to address antimicrobial resistance.<ref>{{cite web |title=The Global Antibiotic Resistance Partnership (GARP) |url=https://www.ducitblue.com/the-garp-project/ |website=Ducit Blue Solutions}}</ref><ref>{{cite web |title=The Evolution of the Global Antibiotic Resistance Partnership |url=http://resistancecontrol.info/2016/rational-use-of-antibiotics/the-evolution-of-the-global-antibiotic-resistance-partnership/ |website=AMR Control- Overcoming Global Antimicrobial Resistance |access-date=12 September 2016}}</ref><ref>{{cite web |title=Antibiotic resistance: AMR a health threat in Uganda |url=https://www.downtoearth.org.in/news/health/antibiotic-resistance-amr-a-health-threat-in-uganda-68932 |website=DownToEarth |access-date=23 January 2020}}</ref><ref>{{cite web |title=Could vaccines save us from antimicrobial resistance? |url=https://www.gavi.org/vaccineswork/could-vaccines-save-us-antimicrobial-resistance |website=Gavi- The Vaccine Alliance |access-date=26 July 2022}}</ref>

=== Modeling Infectious Diseases in Healthcare Network (MInD – Healthcare) ===
One Health Trust was a member of the [[Centers for Disease Control and Prevention|U.S. Centers for Disease Control and Prevention]]'s MInD – Healthcare Network, which supported transmission modeling research to get insights on the drivers of healthcare-associated infections and [[antibiotic-resistant]] infections and estimate the benefits of preventive measures.<ref>{{cite web |title=Modeling Infectious Diseases in Healthcare Network (MInD – Healthcare) |url=https://www.cdc.gov/hai/research/MIND-Healthcare.html |website=Centers for Disease Control and Prevention}}</ref>

=== Affordable Medicines Facility - Malaria ===
The Affordable Medicines Facility — Malaria grew from a 2004 Institute of Medicines (IOM) report co-authored by the One Health Trust's president Dr. Ramanan Laxminarayan.<ref>{{cite web |title=Affordable Medicines Facility-malaria |url=https://en.wikipedia.org/wiki/Affordable_Medicines_Facility-malaria |website=Wikipedia- Affordable Medicines Facility-malaria}}</ref>{{Circular reference|date=May 2024}}<ref>{{cite web |title=A Global Subsidy: Key to Affordable Drugs for Malaria? |url=https://www.healthaffairs.org/doi/10.1377/hlthaff.28.4.949 |website=HealthAffairs |access-date=November 27, 2009}}</ref> The project addressed the issue of rising [[Antimalarial medication|antimalarial drug]] resistance against the most commonly used [[malaria]] treatment at the time, [[chloroquine]], by finding ways to get [[Antimalarial medication|artemisinin-based combination therapies]] — the most effective malaria treatments known — into private pharmacies and village shops.<ref>{{cite web |title=Affordable Medicines Facility-Malaria (AMFm) - CDDEP |url=https://www.resources.org/common-resources/affordable-medicines-facility-malaria-amfm-cddep/ |website=Resources |access-date=20 July 2015}}</ref><ref>{{cite web |title=For malaria, we just can’t afford to use cheap drugs |url=https://www.ft.com/content/30b83428-0dd2-11de-8ea3-0000779fd2ac |website=Financial Times}}</ref>

Through negotiating bulk orders and subsidies, the Affordable Medicines Facility - Malaria team worked to leverage existing private-sector infrastructure in Africa to get artemisinin-based combination therapies where there were none before, to lower prices of effective [[Antimalarial medication|antimalarials]] in rural Africa.<ref>{{cite web |title=Subsidies Help Get Modern Malaria Drugs To Millions In Africa |url=https://www.npr.org/sections/health-shots/2012/09/18/161344518/subsidies-help-get-modern-malaria-drugs-to-millions-in-africa?sc=tw&cc=share/ |website=npr |access-date=19 September 2012}}</ref><ref>{{cite web |title=Effect of the Affordable Medicines Facility—malaria (AMFm) on the availability, price, and market share of quality-assured artemisinin-based combination therapies in seven countries: a before-and-after analysis of outlet survey data |url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)61732-2/fulltext |website=The Lancet |access-date=1 December 2012}}</ref>

=== PhD program in Data Sciences for Global Health in partnership with [[BITS Pilani|Birla Institute of Technology & Science]], [[Pilani]] ===
The One Health Trust, in partnership with [[BITS Pilani|Birla Institute of Technology & Science]] (BITS) in [[Pilani]], India, has a [[Doctor of Philosophy|PhD]] program in Data Sciences for Global Health to provide training in global health issues and research methodology with fieldwork and [[data analysis]].<ref>{{cite web |title=BITS Pilani collaborates with Washington based One Health Trust to offer PhD in Data Sciences |url=https://www.financialexpress.com/jobs-career/education-bits-pilani-collaborates-with-washington-based-one-health-trust-to-offer-phd-in-data-sciences-2920323/ |website=Financial Express |access-date=20 December 2022}}</ref> This program is full-time.<ref>{{cite web |title=BITS Pilani, One Health Trust invite applications for PhD in Data Science for Global Health; check eligibility, how to apply |url=https://indianexpress.com/article/education/bits-pilani-one-health-trust-launch-phd-in-data-science-check-how-to-apply-eligibility-bitsadmission-com-8334488/ |website=The Indian Express |access-date=20 December 2022}}</ref>

=== ResistanceMap ===
The One Health Trust's ResistanceMap is a collection of tools summarizing national and subnational data on antimicrobial use and resistance globally.<ref>{{cite web |title=CDDEP Maps Dangerous Trends in Antibiotic Resistance on a Global Scale |url=https://www.jpiamr.eu/cddep-maps-dangerous-trends-in-antibiotic-resistance-on-a-global-scale-for-the-first-time/ |website=jpiamr |access-date=17 September 2015}}</ref> Since its launch in 2010, ResistanceMap has been used to provide information on trends in drug resistance and antibiotic use.<ref>{{cite web |title=Tracking global trends in the effectiveness of antibiotic therapy using the Drug Resistance Index |url=https://www.eurekalert.org/news-releases/544635 |website=EurekAlert |access-date=17 April 2019}}</ref><ref>{{cite web |title=Antibiotic Resistance Getting Worse Globally, But Fixes Could Be Simple |url=https://www.nationalgeographic.com/science/article/cddep-report-amr |website=National Geographic |access-date=17 September 2015}}</ref>

In 2015, ResistanceMap was updated with a new design interface, expanded tools, and the addition of antibiotic use and resistance data from several low- and middle-income countries in Africa, Asia and [[South America]].<ref>{{cite web |title=CDDEP releases "The State of the World's Antibiotics, 2015" Report |url=https://sidp.org/news/3536391 |website=SIDP- Society of Infectious Diseases Pharmacists |access-date=21 September 2015}}</ref>

=== One World, One Health Podcast ===
The One World, One Health podcast<ref>{{cite web |title=One World, One Health Podcast |url=https://news-decoder.com/a-differerent-kind-of-butterfly-effect/ |archive-date= |access-date=19 September 2024 |website=News Decoder}}</ref> by the One Health Trust was launched in 2022. The podcast is interview-style and the host, Maggie Fox, talks to scientific researchers about topics including pandemics, antimicrobial resistance, the impact of deforestation on human health, among other related issues.

==References==
{{Reflist}}

==External links==
* [http://www.extendingthecure.org/ Extending the Cure (ETC)] {{Webarchive|url=https://web.archive.org/web/20110704192732/http://www.extendingthecure.org/ |date=2011-07-04 }}
* [https://web.archive.org/web/20110212155548/http://www.resistancestrategies.org/ Global Antibiotic Resistance Partnership]

{{authority control}}

{{DEFAULTSORT:One Health Trust}}
[[Category:Medical research institutes in Washington, D.C.]]
[[Category:Organizations established in 2009]]

One Health Trust - Revision history

Bandbaajabarat: Adding first article basic info - done