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{{short description|Dementia research group}}
The '''10/66 Dementia research group''' was founded in the year 1998 at the [[Alzheimer's Disease International]] Annual Conference in [[Cochin]], India. The premise of the research group was that only less than 10% of the population based studies on [[dementia]] were being performed in developing countries where about 66% of population with dementia lived. The 10/66 Dementia Research Group aimed to address this imbalance of researches and to encourage collaborations between research centers in various developing nations and between developed nations and developing nations. <ref name=":0">{{Cite journal |last=Prince |first=Martin J. |date=January 2009 |title=The 10/66 dementia research group - 10 years on |journal=Indian Journal of Psychiatry |volume=51 |issue=Suppl1 |pages=S8–S15 |issn=0019-5545 |pmc=3038536 |pmid=21416024}}</ref>

== Key findings ==

=== Dementia epidemiology ===
The prevalence of dementia varied across different settings. It ranged from 4.8% in rural China to 12.6% in Cuba. Such wide variation was attributed to underreporting in less developed settings. In research settings like rural China care givers were less likely to report the social and functional impairment which formed the basis of diagnosis as per DSM - IV.<ref>{{Cite journal |last1=Rodriguez |first1=Juan J Llibre |last2=Ferri |first2=Cleusa P |last3=Acosta |first3=Daisy |last4=Guerra |first4=Mariella |last5=Huang |first5=Yueqin |last6=Jacob |first6=Ks |last7=Krishnamoorthy |first7=Es |last8=Salas |first8=Aquiles |last9=Sosa |first9=Ana Luisa |last10=Acosta |first10=Isaac |last11=Dewey |first11=Michael E |date=August 2008 |title=Prevalence of dementia in Latin America, India, and China: a population-based cross-sectional survey |journal=The Lancet |language=en |volume=372 |issue=9637 |pages=464–474 |doi=10.1016/S0140-6736(08)61002-8 |pmc=2854470 |pmid=18657855}}</ref> The incidence rate of 10/66 dementia varied between 18.2 per 1000 person-years in Peru to 30.4 per 1000 person-years in Mexico. This was found to be 1.4–2.7 times higher than the incidence reported in DSM-IV dementia. Male sex, higher educational achievement were revealed to be protective factors for dementia. This gave even more supporting evidence for the cognitive reserve hypothesis. <ref>{{Cite journal |last1=At |first1=Jotheeswaran |last2=Bryce |first2=Renata |last3=Prina |first3=Matthew |last4=Acosta |first4=Daisy |last5=Ferri |first5=Cleusa P |last6=Guerra |first6=Mariella |last7=Huang |first7=Yueqin |last8=Rodriguez |first8=Juan J. Llibre |last9=Salas |first9=Aquiles |last10=Sosa |first10=Ana Luisa |last11=Williams |first11=Joseph D. |date=December 2015 |title=Frailty and the prediction of dependence and mortality in low- and middle-income countries: a 10/66 population-based cohort study |journal=BMC Medicine |language=en |volume=13 |issue=1 |pages=138 |doi=10.1186/s12916-015-0378-4 |issn=1741-7015 |pmc=4481121 |pmid=26063168 |doi-access=free }}</ref><ref>{{Cite journal |last1=Prince |first1=Martin |last2=Acosta |first2=Daisy |last3=Ferri |first3=Cleusa P |last4=Guerra |first4=Mariella |last5=Huang |first5=Yueqin |last6=Rodriguez |first6=Juan J Llibre |last7=Salas |first7=Aquiles |last8=Sosa |first8=Ana Luisa |last9=Williams |first9=Joseph D |last10=Dewey |first10=Michael E |last11=Acosta |first11=Isaac |date=July 2012 |title=Dementia incidence and mortality in middle-income countries, and associations with indicators of cognitive reserve: a 10/66 Dementia Research Group population-based cohort study |journal=The Lancet |language=en |volume=380 |issue=9836 |pages=50–58 |doi=10.1016/S0140-6736(12)60399-7 |pmc=3525981 |pmid=22626851}}</ref>

=== Mental health ===
Evidence on the prevalence of various Mental health disorders like [[Anxiety disorder|anxiety]] and [[Major depressive disorder|depressive disorders]] among older adults living in low- and middle-income countries was also very limited. The prevalence of depression was reported to vary from a 0.3% to 13.8%.<ref>{{Cite journal |last1=Castro-Costa |first1=Erico |last2=Dewey |first2=Michael |last3=Stewart |first3=Robert |last4=Banerjee |first4=Sube |author-link4=Sube Banerjee |last5=Huppert |first5=Felicia |last6=Mendonca-Lima |first6=Carlos |last7=Bula |first7=Christophe |last8=Reisches |first8=Friedel |last9=Wancata |first9=Johannes |last10=Ritchie |first10=Karen |last11=Tsolaki |first11=Magda |date=November 2007 |title=Prevalence of depressive symptoms and syndromes in later life in ten European countries: The SHARE study |journal=British Journal of Psychiatry |language=en |volume=191 |issue=5 |pages=393–401 |doi=10.1192/bjp.bp.107.036772 |issn=0007-1250 |pmid=17978318 |s2cid=36676042 |doi-access=free}}</ref> The prevalence of anxiety was similar to ICD-10 depression estimates. <ref>{{Cite journal |last1=Prina |first1=A. Matthew |last2=Ferri |first2=Cleusa P. |last3=Guerra |first3=Mariella |last4=Brayne |first4=Carol |last5=Prince |first5=Martin |date=December 2011 |title=Prevalence of anxiety and its correlates among older adults in Latin America, India and China: cross-cultural study |journal=British Journal of Psychiatry |language=en |volume=199 |issue=6 |pages=485–491 |doi=10.1192/bjp.bp.110.083915 |issn=0007-1250 |pmc=3227807 |pmid=22016438}}</ref>

=== Non‑communicable diseases ===
[[Hypertension]] was the most common diagnosis (63.6% overall), followed by frailty (15.2%), dementia (8.7%), [[stroke]] (7.1%), depression (4.7%) and [[Ischaemic Heart Disease|ischaemic heart disease]] (4.4%) <ref>{{Cite journal |last1=Sousa |first1=Renata M |last2=Ferri |first2=Cleusa P |last3=Acosta |first3=Daisy |last4=Guerra |first4=Mariella |last5=Huang |first5=Yueqin |last6=Jacob |first6=Ks |last7=Jotheeswaran |first7=At |last8=Hernandez |first8=Milagros A Guerra |last9=Liu |first9=Zhaorui |last10=Pichardo |first10=Guillermina Rodriguez |last11=Rodriguez |first11=Juan J Llibre |date=December 2010 |title="The contribution of chronic diseases to the prevalence of dependence among older people in Latin America, China and India: a 10/66 Dementia Research Group population-based survey" |journal=BMC Geriatrics |language=en |volume=10 |issue=1 |pages=53 |doi=10.1186/1471-2318-10-53 |issn=1471-2318 |pmc=2923155 |pmid=20691064 |doi-access=free }}</ref>

==References==
{{reflist}}

[[Category:Alzheimer's and dementia organizations]]

Dementia 10/66 - Revision history

Gopalpurpp: Adding Info.