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{{Short description|Indian microbiologist}}
{{Use dmy dates|date=September 2019}}
{{Use Indian English|date=September 2019}}
{{Infobox scientist
| name = Amit Singh
| image =
| alt =
| caption =
| birth_date = {{birth date and age|1976|3|18}}
| birth_place = India
| death_date =
| death_place =
| fields = {{ublist | [[Microbiology]] }}
| workplaces = {{ublist | [[International Centre for Genetic Engineering and Biotechnology]] | [[Indian Institute of Science]] }}
| alma_mater = {{ublist| [[Indian Institute of Technology Roorkee]] |[[University of Delhi#South Campus|University of Delhi South Campus]] | [[University of Alabama at Birmingham]] }}
| doctoral_advisor = {{ublist|[[Anil Kumar Tyagi]] | Adrie JC Steyn }}
| doctoral_students =
| known_for = [[Mycobacterium tuberculosis]] pathogenesis
| awards = {{ublist| | 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]]| 2017/18 [[National Bioscience Award for Career Development|N-BIOS Prize]] }}
}}

'''Amit Singh''' (born 18 March 1976) is an Indian [[microbiologist]] and professor in the Department of Microbiology & Cell Biology at the [[Indian Institute of Science]]. His research focuses on [[pathogenesis]], including drug resistance mechanisms in both [[mycobacterium tuberculosis]] (TB) and [[HIV|human immunodeficiency viruses (HIV)]].

== Biography ==
Amit Singh was born on 18 March 1976.<ref>{{cite news |date=26 November 2021 |title=Scientist Amit Singh |url=https://nikhilbharat.com/biography-of-scientist-amit-singh-in-hindi/ |archive-url=https://web.archive.org/web/20220108225224/https://nikhilbharat.com/biography-of-scientist-amit-singh-in-hindi/ |archive-date=8 January 2022 |newspaper=Hindi Info World}}</ref> He earned a Bachelor of Science from the [[University of Delhi]], and a master's in [[Biotechnology]] from the [[IIT Roorkee|Indian Institute of Technology Roorkee]].<ref name="Centre for Infectious Disease Research (CIDR)2">{{Cite web|url=http://cidr.iisc.ernet.in/amit/Group-Leader.html|title=Centre for Infectious Disease Research (CIDR)|date=2019-01-11|website=cidr.iisc.ernet.in|access-date=2019-01-11|archive-url=https://web.archive.org/web/20190112150057/http://cidr.iisc.ernet.in/amit/Group-Leader.html|archive-date=2019-01-12}}</ref> In 2004, he completed a PhD under the supervision of Professor [[Anil Kumar Tyagi]] at the University of Delhi [[University of Delhi#South Campus|South Campus]]. Subsequently, he conducted postdoctoral research in the lab of Dr. Adrie JC Steyn at the [[University of Alabama in Birmingham]] (UAB).<ref>{{Cite web |title=India Alliance - Advancing Discovery & Innovation to Improve Health |url=https://www.indiaalliance.org/fellow/amit-singh |access-date=2025-03-13 |website=www.indiaalliance.org}}</ref>

Upon returning to India in 2010 Singh held a Wellcome Trust-DBT Intermediate Fellowship at the [[International Centre for Genetic Engineering and Biotechnology]]. In January 2014 he became an assistant professor of [[microbiology]] and [[cell biology]] at the [[Indian Institute of Science]] (IISc).<ref name="MCB2">{{Cite web|url=http://mcbl.iisc.ac.in/Amit-Singh.html|title=MCB|date=2019-01-11|website=mcbl.iisc.ac.in|access-date=2019-01-11|archive-date=13 January 2019|archive-url=https://web.archive.org/web/20190113003823/http://mcbl.iisc.ac.in/Amit-Singh.html}}</ref> He leads a research group at the Centre for Infectious Disease Research,<ref name="Centre for Infectious Disease Research (CIDR) Group Leader2">{{Cite web|url=http://cidr.iisc.ernet.in/amit/Group-Leader.html|title=Centre for Infectious Disease Research (CIDR) Group Leader|date=2019-01-11|website=cidr.iisc.ernet.in|access-date=2019-01-11|archive-url=https://web.archive.org/web/20190112150057/http://cidr.iisc.ernet.in/amit/Group-Leader.html|archive-date=2019-01-12}}</ref> investigating the mechanisms of [[Chronic condition|chronic human infections]] with a focus on [[Mycobacterium tuberculosis]] and [[human immunodeficiency virus]] (HIV).<ref name="Centre for Infectious Disease Research (CIDR) fellows2">{{Cite web|url=http://cidr.iisc.ac.in/amit/Postdoctoral-Fellow.html|title=Centre for Infectious Disease Research (CIDR) fellows|date=2019-01-11|website=cidr.iisc.ac.in|access-date=2019-01-11|archive-url=https://web.archive.org/web/20180703065827/http://cidr.iisc.ac.in/amit/Postdoctoral-Fellow.html|archive-date=3 July 2018}}</ref><ref name="Welcome to lab web page of Dr. Amit Singh2">{{Cite web|url=http://cidr.iisc.ac.in/amit/index.html|title=Welcome to lab web page of Dr. Amit Singh|date=2019-01-11|website=cidr.iisc.ac.in|access-date=2019-01-11|archive-url=https://web.archive.org/web/20181004043538/http://cidr.iisc.ac.in/amit/index.html|archive-date=4 October 2018}}</ref><ref name="Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection2">{{Cite journal|last1=Bhaskar|first1=Ashima|last2=Chawla|first2=Manbeena|last3=Mehta|first3=Mansi|last4=Parikh|first4=Pankti|last5=Chandra|first5=Pallavi|last6=Bhave|first6=Devayani|last7=Kumar|first7=Dhiraj|last8=Carroll|first8=Kate|last9=Singh|first9=Amit|date=2014|title=Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection|journal=PLOS Pathogens|volume=10|issue=1|article-number=e1003902|doi=10.1371/journal.ppat.1003902|pmc=3907381|pmid=24497832|doi-access=free}}</ref>

== Awards ==
Singh has held a Wellcome Trust-DBT Senior Fellowship since 2016.<ref name="India Alliance - About Fellow2">{{Cite web|url=https://www.indiaalliance.org/fellowsprofile/dr-amit-singh-132|title=India Alliance - About Fellow|date=2019-01-11|website=www.indiaalliance.org|access-date=2019-01-11}}</ref><ref>{{Cite web|url=http://cidr.iisc.ac.in/amit/publication/|title=Amit Singh Group, Indian Institute of Science, Bangalore -- Publication.|access-date=8 May 2019}}</ref> He received the 2017/18 [[National Bioscience Award for Career Development]] from the [[Department of Biotechnology]] of the [[Government of India]].<ref name="Awardees of National Bioscience Awards for Career Development2">{{Cite web|url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf|title=Awardees of National Bioscience Awards for Career Development|date=2016|publisher=Department of Biotechnology|access-date=2017-11-20|archive-date=4 March 2018|archive-url=https://web.archive.org/web/20180304191331/http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf}}</ref>

Singh is a co-inventor on a patent titled "Shortening Tuberculosis Therapy and Reducing Relapse by Co-administering Chloroquine in TB and HIV-TB Co-infected Conditions," filed in 2020 and published in 2021.

In 2021, Singh was awarded the [[Shanti Swarup Bhatnagar Prize for Science and Technology]] for his contributions to understanding host-pathogen interactions in [[Mycobacterium tuberculosis]] and HIV.<ref name="sbprize">{{cite web |title=Shanti Swarup Bhatnagar Prize (SSB) for Science and Technology 2021 |url=https://ssbprize.gov.in/WriteReadData/LatestUpdates/202109260133259214500SSBPrize2021Website.pdf |access-date=26 September 2021 |website=sbprize.gov.in |publisher=[[Council of Scientific and Industrial Research]]}}</ref> In 2022, Singh was included in the [[Asian Scientist 100]] list.

== Publications ==
=== Most cited articles at University of Alabama ===
* {{cite journal | pmid = 19680450 | doi=10.1371/journal.ppat.1000545 | volume=5 | title=Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response | pmc=2718811 | year=2009 | journal=PLOS Pathog | article-number=e1000545 | last1 = Singh | first1 = A | last2 = Crossman | first2 = DK | last3 = Mai | first3 = D | last4 = Guidry | first4 = L | last5 = Voskuil | first5 = MI | last6 = Renfrow | first6 = MB | last7 = Steyn | first7 = AJ| issue=8 | doi-access=free }} (Cited by 204 articles according to [[Google Scholar]].)
* {{cite journal | pmid = 17609386 | doi=10.1073/pnas.0700490104 | volume=104 | title=Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival | pmc=1906726 | year=2007 | journal=Proc Natl Acad Sci U S A | pages=11562–7 | last1 = Singh | first1 = A | last2 = Guidry | first2 = L | last3 = Narasimhulu | first3 = KV | last4 = Mai | first4 = D | last5 = Trombley | first5 = J | last6 = Redding | first6 = KE | last7 = Giles | first7 = GI | last8 = Lancaster | first8 = JR Jr | last9 = Steyn | first9 = AJ| issue=28 | bibcode=2007PNAS..10411562S | doi-access=free }} (Cited by 154 articles according to Google Scholar.)

=== Most cited articles at IISc ===
* Ashima Bhaskar, Manbeena Chawla, Mansi Mehta, Pankti Parikh, Pallavi Chandra, Devayani Bhave, Dhiraj Kumar, Kate S Carroll, Amit Singh. Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection. 2014. ''[[PLOS Pathogens]]''. 10:1 e1003902. (Cited by 88 articles according to Google Scholar.)
* Rufai SB, Kumar P, Singh A, Prajapati S, Balooni V, Singh S. Comparison of Xpert MTB/RIF with line probe assay for detection of rifampin-monoresistant Mycobacterium tuberculosis. ''[[Journal of Clinical Microbiology|Journal of clinical microbiology]]''. 2014 June; '''52''' (6): 1846–52. (Cited by 76 articles according to Google Scholar.)
* Chawla M, Parikh P, Saxena A, Munshi M, Mehta M, Mai D, Srivastava AK, Narasimhulu KV, Redding KE, Vashi N, Kumar D. Adrie JC Steyn and Amit Singh. Mycobacterium tuberculosis WhiB4 regulates [[oxidative stress]] response to modulate survival and dissemination in vivo. ''[[Molecular Microbiology (journal)|Molecular microbiology]]''. 2012 September; '''85''' (6): 1148–65. (Cited by 56 articles according to Google Scholar.)

== References ==
{{reflist}}

== Further reading ==
* {{Cite news|url=https://www.thehindu.com/sci-tech/science/iisc-team-finds-new-approaches-to-kill-tb-bacteria/article25081705.ece|title=IISc team finds new approaches to kill TB bacteria|last=Prasad|first=R.|date=2018-09-29|newspaper=The Hindu|access-date=2019-01-11|language=en-IN}}
* {{Cite web|url=https://researchmatters.in/article/how-do-tb-bacteria-develop-resistance-common-antibiotics-new-study-iisc-attempts-answer|title=How do TB bacteria develop resistance to common antibiotics? A new study at IISc attempts to answer this|date=2017-07-06|website=Research Matters|language=en|access-date=2019-01-11}}

== External links ==
* [http://cidr.iisc.ac.in/amit/ Official home page at IISc]
{{N-BIOS Laureates 2010–2019}}
{{SSBPST recipients in Biological Science}}

{{authority control}}

{{DEFAULTSORT:Singh, Amit}}
[[Category:N-BIOS Prize recipients]]
[[Category:Indian immunologists]]
[[Category:Indian microbiologists]]
[[Category:Indian virologists]]
[[Category:Academic staff of the Indian Institute of Science]]
[[Category:Delhi University alumni]]
[[Category:IIT Roorkee alumni]]
[[Category:University of Alabama at Birmingham alumni]]
[[Category:Living people]]
[[Category:1976 births]]

Amit Singh (scientist) - Revision history

StevieBavin8727: new some bio added tags!